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Beyond contact toxicity: Volatile and systemic nematode suppression by ‘Candidatus Pseudomonas auctus’ JDE115 in soybean Cover

Beyond contact toxicity: Volatile and systemic nematode suppression by ‘Candidatus Pseudomonas auctus’ JDE115 in soybean

Open Access
|Oct 2026

References

  1. Abd El-Rahman, A. F., Shaheen, H. A., Abd El-Aziz, R. M., and Ibrahim, D. S. S. 2019. Influence of hydrogen cyanide-producing rhizobacteria in controlling the crown gall and root-knot nematode, Meloidogyne incognita. Egyptian Journal of Biological Pest Control, 29(1):41. Available at: https://doi.org/10.1186/s41938-019-0143-7.
  2. Ahmad, M. F., Ahmad, F. A., Alsayegh, A. A., Zeyaullah, M., AlShahrani, A. M., Muzammil, K., et al. 2024. Pesticides impacts on human health and the environment with their mechanisms of action and possible countermeasures. Heliyon, 10(7):e29128. Available at: https://doi.org/10.1016/j.heliyon.2024.e29128.
  3. Anand, A., Chinchilla, D., Tan, C., Mène-Saffrané, L., L’Haridon, F., and Weisskopf, L. 2020. Contribution of hydrogen cyanide to the antagonistic activity of Pseudomonas strains against Phytophthora infestans. Microorganisms, 8(8):1144. Available at: https://doi.org/10.3390/microorganisms8081144.
  4. Arjoune, Y., Sugunaraj, N., Peri, S., Nair, S. V., Skurdal, A., Ranganathan, P., et al. 2022. Soybean cyst nematode detection and management: a review. Plant Methods, 18(1):110. Available at: https://doi.org/10.1186/s13007-022-00933-8.
  5. Bakker, W. 1987. Microbial cyanide production in the rhizosphere in relation to potato yield reduction and Pseudomonas spp-mediated plant growth-stimulation. Soil Biology and Biochemistry, 19(4):451–457.
  6. Bargmann, C. I., Hartwieg, E. and Horvitz, H. R. 1993. Odorant-selective genes and neurons mediate olfaction in C. elegans. Cell, 74(3):515–527. Available at: https://doi.org/10.1016/0092-8674(93)80053-H.
  7. Barros, A. F., Campos, V. P., Da Silva, J. C. P., Pedroso, M. P., Medeiros, F. H. V., Pozza, E. A., et al. 2014. Nematicidal activity of volatile organic compounds emitted by Brassica juncea, Azadirachta indica, Canavalia ensiformis, Mucuna pruriens and Cajanus cajan against Meloidogyne incognita. Applied Soil Ecology, 80:34–43. Available at: https://doi.org/10.1016/j.apsoil.2014.02.011.
  8. Bennett, J. O., Krishnan, A. H., Wiebold, W. J., and Krishnan, H. B. 2003. Positional effect on protein and oil content and composition of soybeans. Journal of Agricultural and Food Chemistry, 51(23):6882–6886. Available at: https://doi.org/10.1021/jf034371l.
  9. Bhat, A. A., Shakeel, A., Waqar, S., Handoo, Z. A., and Khan, A. A. 2023. Microbes vs. nematodes: insights into biocontrol through antagonistic organisms to control root-knot nematodes. Plants, 12(3):451. Available at: https://doi.org/10.3390/plants12030451.
  10. Blumer, C. and Haas, D. 2000. Mechanism, regulation, and ecological role of bacterial cyanide biosynthesis. Archives of Microbiology, 173(3):170–177. Available at: https://doi.org/10.1007/s002039900127.
  11. Bradley, C. A., Allen, T. W., Sisson, A. J., Bergstrom, G. C., Bissonnette, K. M., Bond, J., et al. 2021. Soybean yield loss estimates due to diseases in the United States and Ontario, Canada, from 2015 to 2019. Plant Health Progress, 22(4):483–495. Available at: https://doi.org/10.1094/PHP-01-21-0013-RS.
  12. Byrd, D. W., Barker, K. R., Ferris, H., Nusbaum, C. J., Griffin, W. E., Small, R. H., et al. 1976. Two semi-automatic elutriators for extracting nematodes and certain fungi from soil. Journal of Nematology, 8(3):206–212.
  13. Castric, P. A. 1977. Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis. Journal of Bacteriology, 130(2):826–831. Available at: https://doi.org/10.1128/jb.130.2.826-831.1977.
  14. Chen, J., Li, Q. X., and Song, B. 2020. Chemical Nematicides: Recent research progress and outlook. Journal of Agricultural and Food Chemistry, 68(44):12175–12188. Available at: https://doi.org/10.1021/acs.jafc.0c02871.
  15. Cheng, W., Yang, J., Nie, Q., Huang, D., Yu, C., Zheng, L., et al. 2017. Volatile organic compounds from Paenibacillus polymyxa KM2501-1 control Meloidogyne incognita by multiple strategies. Scientific Reports, 7(1):16213. Available at: https://doi.org/10.1038/s41598-017-16631-8.
  16. Choi, A. H. K., Slamti, L., Avci, F. Y., Pier, G. B., and Maira-Litrán, T. 2009. The pgaABCD locus of Acinetobacter baumannii encodes the production of poly-β-1-6- N -acetylglucosamine, which is critical for biofilm formation. Journal of Bacteriology, 191(19):5953–5963. Available at: https://doi.org/10.1128/JB.00647-09.
  17. Deng, X., Wang, X. and Li, G. 2022. Nematicidal effects of volatile organic compounds from microorganisms and plants on plant-parasitic nematodes. Microorganisms, 10(6):1201. Available at: https://doi.org/10.3390/microorganisms10061201.
  18. Desaeger, J., Wram, C. and Zasada, I. 2020. New reduced-risk agricultural nematicides - rationale and review. Journal of Nematology, 52(1):1–16. Available at: https://doi.org/10.21307/jofnem-2020-091.
  19. Dupont, C. A., Bourigault, Y., Osmond, T., Nier, M., Barbey, C., Latour, X., et al. 2023. Pseudomonas fluorescens MFE01 uses 1-undecene as aerial communication molecule. Frontiers in Microbiology, 14:1264801. Available at: https://doi.org/10.3389/fmicb.2023.1264801.
  20. Eisenback, J. D. 2022. Nematology 101 super course. Unit One, Introduction and history. 1st ed. Blacksburg, VA: Mactode Publications.
  21. Fadiji, A. E., and Babalola, O. O. 2020. Elucidating mechanisms of endophytes used in plant protection and other bioactivities with multifunctional prospects. Frontiers in Bioengineering and Biotechnology, 8:467. Available at: https://doi.org/10.3389/fbioe.2020.00467.
  22. Faske, T. R., Mueller, J., Becker, J. O., Bernard, E. C., Bradley, C., Bond, J., et al. 2023. summarized distribution of the southern root-knot nematode, Meloidogyne incognita, in field crops in the United States. Plant Health Progress, 24(4):522–524. Available at: https://doi.org/10.1094/PHP-04-23-0031-BR.
  23. Flores-Duarte, N. J., Caballero-Delgado, S., Pajuelo, E., Mateos-Naranjo, E., Redondo-Gómez, S., Navarro-Torre, S., and et al. 2022. Enhanced legume growth and adaptation to degraded estuarine soils using Pseudomonas sp. nodule endophytes. Frontiers in Microbiology, 13:1005458. Available at: https://doi.org/10.3389/fmicb.2022.1005458.
  24. Gómez-Tenorio, M. A., Zanón, M. J., De Cara, M., Lupión, B., and Tello, J. C. 2015. Efficacy of dimethyl disulfide (DMDS) against Meloidogyne sp. and three formae speciales of Fusarium oxysporum under controlled conditions. Crop Protection, 78:263–269. Available at: https://doi.org/10.1016/j.cropro.2015.09.013.
  25. Gorny, A. M., Ye, W., Cude, S. and Thiessen, L. 2021. Soybean root-knot nematode: A diagnostic guide. Plant Health Progress, 22(2):164–175. Available at: https://doi.org/10.1094/PHP-01-21-0005-DG.
  26. Haarith, D., Kim, D., Chen, S., and Bushley, K. E. 2021. Growth chamber and greenhouse screening of promising in vitro fungal biological control candidates for the soybean cyst nematode (Heterodera glycines). Biological Control, 160:104635. Available at: https://doi.org/10.1016/j.biocontrol.2021.104635.
  27. Haney, C. H., Wiesmann, C. L., Shapiro, L. R., Melnyk, R. A., O’Sullivan, L. R., Khorasani, S., et al. 2018. Rhizosphere-associated Pseudomonas induce systemic resistance to herbivores at the cost of susceptibility to bacterial pathogens, Molecular Ecology, 27(8):1833–1847. Available at: https://doi.org/10.1111/mec.14400
  28. Hussein, S. N., Safaie, N., Shams-bakhsh, M., and Al-Juboory, H. H. 2024. Harnessing rhizobacteria: Isolation, identification, and antifungal potential against soil pathogens. Heliyon, 10(15): e35430. Available at: https://doi.org/10.1016/j.heliyon.2024.e35430.
  29. Ibañez, F., Arroyo, M. E., Angelini, J., Tonelli, M. L., Muñoz, V., Ludueña, L., et al. 2014. Non-rhizobial peanut nodule bacteria promote maize (Zea mays L.) and peanut (Arachis hypogaea L.) growth in a simulated crop rotation system. Applied Soil Ecology, 84:208–212. Available at: https://doi.org/10.1016/j.apsoil.2014.08.002.
  30. Ilieva, Z., Lazarova, T., Mitev, A., and Myrta, A. 2021. Monitoring of long-lasting effects of fumigation with dimethyl disulfide (DMDS) on root-gall index, root-knots, other nematode populations, and crop yield over three protected cucumber crops in Bulgaria. Agronomy, 11(6):1206. Available at: https://doi.org/10.3390/agronomy11061206.
  31. Itoh, Y., Rice, J. D., Goller, C., Pannuri, A., Taylor, J., Meisner, J., et al. 2008. Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-β-1,6- N -Acetyl- d -glucosamine. Journal of Bacteriology, 190(10):3670–3680. Available at: https://doi.org/10.1128/JB.01920-07.
  32. Jiang, E. Y., Sukhbaatar, O., Zhang, M. Z., Zhang, W. H., and Gu, Y. C. 2024. Selectivin: A nematicide from parasitic nematodes-specifically activated chemical. Advanced Agrochem, 3(2):111–114. Available at: https://doi.org/10.1016/j.aac.2024.01.006.
  33. Jones, R. A. C. 2021. Global plant virus disease pandemics and epidemics. Plants, 10(2):233. Available at: https://doi.org/10.3390/plants10020233.
  34. Kang, B. R., Anderson, A. J., and Kim, Y. C. 2018. Hydrogen cyanide produced by Pseudomonas chlororaphis O6 exhibits nematicidal activity against Meloidogyne hapla. The Plant Pathology Journal, 34(1):35–43. Available at: https://doi.org/10.5423/PPJ.OA.06.2017.0115.
  35. Kantor, C., Eisenback, J. D., and Kantor, M. 2024. Biosecurity risks to human food supply associated with plant-parasitic nematodes. Frontiers in Plant Science, 15:1404335. Available at: https://doi.org/10.3389/fpls.2024.1404335.
  36. Kantor, M., Handoo, Z., Kantor, C., and Carta, L. 2022. Top ten most important U.S.-regulated and emerging plant-parasitic nematodes. Horticulturae, 8(3):208. Available at: https://doi.org/10.3390/horticulturae8030208.
  37. Karges, K., Bellingrath-Kimura, S. D., Watson, C. A., Stoddard, F. L., Halwani, M., and Reckling, M. 2022. Agro-economic prospects for expanding soybean production beyond its current northerly limit in Europe. European Journal of Agronomy, 133:126415. Available at: https://doi.org/10.1016/j.eja.2021.126415.
  38. Karuri, H. W., Olago, D., Neilson, R., Mararo, E., and Villinger, J. 2017. A survey of root knot nematodes and resistance to Meloidogyne incognita in sweet potato varieties from Kenyan fields. Crop Protection, 92:114–121. Available at: https://doi.org/10.1016/j.cropro.2016.10.020.
  39. Khan, M. R., Mohidin, F. A., Khan, U., and Ahamad, F. 2016. Native Pseudomonas spp. suppressed the root-knot nematode in in vitro and in vivo, and promoted the nodulation and grain yield in the field grown Mungbean. Biological Control, 101:159–168. Available at: https://doi.org/10.1016/j.biocontrol.2016.06.012.
  40. Knowles, C. J. 1976. Microorganisms and cyanide, BACTERIOL. REV., 40.
  41. Kuhl-Nagel, T., Rodriguez, P. A., Gantner, I., Chowdhury, S. P., Schwehn, P., Rosenkranz, M., et al. 2022. Novel Pseudomonas sp. SCA7 promotes plant growth in two plant families and induces systemic resistance in Arabidopsis thaliana. Frontiers in Microbiology, 13:923515. Available at: https://doi.org/10.3389/fmicb.2022.923515
  42. Laville, J., Blumer, C., Von Schroetter, C., Gaia, V., Défago, G., Keel, C., and et al. 1998. Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0. Journal of Bacteriology, 180(12):3187–3196. Available at: https://doi.org/10.1128/JB.180.12.3187-3196.1998.
  43. Lee, Y. S., Nguyen, X. H., Naing, K. W., Park, Y. S., and Kim, K. Y. 2015. Role of lytic enzymes secreted by Lysobacter capsici YS1215 in the control of root-knot nematode of tomato plants. Indian Journal of Microbiology, 55(1):74–80. Available at: https://doi.org/10.1007/s12088-014-0499-z.
  44. Li, P., Tedersoo, L., Crowther, T. W., Wang, B., Shi, Y., Kuang, L., et al. 2023. Global diversity and biogeography of potential phytopathogenic fungi in a changing world. Nature Communications, 14(1):6482. Available at: https://doi.org/10.1038/s41467-023-42142-4.
  45. Li, T. J., Wang, D. Y., Li, B. X., and Wu, H. Y. 2022. The hatching of cereal cyst nematode (Heterodera avenae) in response to different inorganic ions. Scientia Agricola, 79(1): e20200072. Available at: https://doi.org/10.1590/1678-992x-2020-0072.
  46. Liu, A., Zhang, P., Bai, B., Bai, F., Jin, T., and Ren, J. 2020. Volatile Organic compounds of endophytic Burkholderia pyrrocinia strain JK-SH007 promote disease resistance in poplar. Plant Disease, 104(6):1610–1620. Available at: https://doi.org/10.1094/PDIS-11-19-2366-RE.
  47. Lyngberg, L., Healy, J., Bartlett, W., Miller, S., Conway, S. J., Booth, I. R., and et al. 2011. KefF, the regulatory subunit of the potassium efflux system kefC, shows quinone oxidoreductase activity. Journal of Bacteriology, 193(18):4925–4932. Available at: https://doi.org/10.1128/JB.05272-11.
  48. Lyons, R., Hammond-Kosack, K. E., and Kanyuka, K. 2008. Identification and characterization of a novel efficient resistance response to the furoviruses SBWMV and SBCMV in barley. Molecular Plant-Microbe Interactions®, 21(9):1193–1204. Available at: https://doi.org/10.1094/MPMI-21-9-1193.
  49. Majidian, P., Ghorbani, H. R. and Farajpour, M. 2024. Achieving agricultural sustainability through soybean production in Iran: Potential and challenges. Heliyon, 10(4): e26389. Available at: https://doi.org/10.1016/j.heliyon.2024.e26389.
  50. Marin-Bruzos, M., Grayston, S. J., Forge, T., and Nelson, L. M. 2021. Isolation and characterization of streptomycetes and pseudomonad strains with antagonistic activity against the plant parasitic nematode Pratylenchus penetrans and fungi associated with replant disease. Biological Control, 158:104599. Available at: https://doi.org/10.1016/j.biocontrol.2021.104599.
  51. Mazzuchelli, R. D. C. L., Mazzuchelli, E. H. L., and Araujo, F. F. D. 2020. Efficiency of Bacillus subtilis for root-knot and lesion nematodes management in sugarcane. Biological Control, 143:104185. Available at: https://doi.org/10.1016/j.biocontrol.2020.104185.
  52. McCarville, M. T., Marett, C. C., Mullaney, M. P., Gebhart, G. D., and Tylka, G. L. 2017. Increase in soybean cyst nematode virulence and reproduction on resistant soybean varieties in Iowa from 2001 to 2015 and the effects on soybean yields. Plant Health Progress, 18(3):146–155. Available at: https://doi.org/10.1094/PHP-RS-16-0062.
  53. Mendoza, A. R., Kiewnick, S., and Sikora, R. A. 2008. In vitro activity of Bacillus firmus against the burrowing nematode Radopholus similis, the root-knot nematode Meloidogyne incognita and the stem nematode Ditylenchus dipsaci. Biocontrol Science and Technology, 18(4):377–389. Available at: https://doi.org/10.1080/09583150801952143.
  54. Mishra, R., Tripathi, M. K., Sikarwar, R. S., Singh, Y. and Tripathi, N. 2024. Soybean (Glycine max L. Merrill): A Multipurpose legume shaping our world. Plant cell biotechnology and molecular biology, 25(3–4):17–37. https://doi.org/10.56557/pcbmb/2024/v25i3-48643.
  55. Montejano-Ramírez, V., Ávila-Oviedo, J. L., Campos-Mendoza, F. J., and Valencia-Cantero, E. 2024. Microbial volatile organic compounds: insights into plant defense. Plants, 13(15):2013. Available at: https://doi.org/10.3390/plants13152013.
  56. Nagashima, A., Higaki, T., Koeduka, T., Ishigami, K., Hosokawa, S., Watanabe, H., et al. 2019. Transcriptional regulators involved in responses to volatile organic compounds in plants. Journal of Biological Chemistry, 294(7):2256–2266. Available at: https://doi.org/10.1074/jbc.RA118.005843.
  57. Nandi, M., Selin, C., Brassinga, A. K. C., Belmonte, M. F., Fernando, W. G. D., Loewen, P. C., and et al. 2015. Pyrrolnitrin and hydrogen cyanide production by Pseudomonas chlororaphis strain PA23 exhibits nematicidal and repellent activity against Caenorhabditis elegans. PLoS One, 10(4): e0123184. Available at: https://doi.org/10.1371/journal.pone.0123184.
  58. Opdensteinen, P., Charudattan, R., Hong, J. C., Rosskopf, E. N., and Steinmetz, N. F. 2024. Biochemical and nanotechnological approaches to combat phytoparasitic nematodes. Plant Biotechnology Journal, 22(9):2444–2460. Available at: https://doi.org/10.1111/pbi.14359.
  59. Pfeilmeier, S., Caly, D. L., and Malone, J. G. 2016. Bacterial pathogenesis of plants: future challenges from a microbial perspective: Challenges in bacterial molecular plant pathology. Molecular Plant Pathology, 17(8):1298–1313. Available at: https://doi.org/10.1111/mpp.12427.
  60. Pieterse, C. M. J., Pelt, J. A. V., Keurentjes, J. J. B., Verhagen, B. W. M., Knoester, M., and Loon, L.C.V. 2001. Rhizobacteria-mediated induced systemic resistance: Triggering, signalling and expression. European Journal of Plant Pathology, 107:51–61.
  61. Pieterse, C. M. J., Zamioudis, C., Berendsen, R. L., Weller, D. M., Van Wees, S. C. M., and Bakker, P. A. H. M. 2014. Induced systemic resistance by beneficial microbes. Annual Review of Phytopathology, 52(1):347–375. Available at: https://doi.org/10.1146/annurev-phyto-082712-102340.
  62. Popova, A. A., Koksharova, O. A., Lipasova, V. A., Zaitseva, J. V., Katkova-Zhukotskaya, O. A., Eremina, S. I., et al. 2014. Inhibitory and toxic effects of volatiles emitted by strains of Pseudomonas and Serratia on growth and survival of selected microorganisms, Caenorhabditis elegans, and Drosophila melanogaster. BioMed Research International, 2014:1–11. Available at: https://doi.org/10.1155/2014/125704.
  63. Poulin, M. B., and Kuperman, L. L. 2021. Regulation of biofilm exopolysaccharide production by cyclic di-guanosine monophosphate. Frontiers in Microbiology, 12:730980. Available at: https://doi.org/10.3389/fmicb.2021.730980.
  64. Poveda, J., Abril-Urias, P., and Escobar, C. 2020. Biological control of plant-parasitic nematodes by filamentous fungi inducers of resistance: Trichoderma, mycorrhizal and endophytic fungi. Frontiers in Microbiology, 11:992. Available at: https://doi.org/10.3389/fmicb.2020.00992.
  65. Prakash, D., Ms, A., Radhika, B., Venkatesan, R., Chalasani, S. H., and Singh, V. 2021. 1‐Undecene from Pseudomonas aeruginosa is an olfactory signal for flight‐or‐fight response in Caenorhabditis elegans. The EMBO Journal, 40(13): e106938. Available at: https://doi.org/10.15252/embj.2020106938.
  66. Proença, D. N., Heine, T., Senges, C. H. R., Bandow, J. E., Morais, P. V., and Tischler, D. 2019. Bacterial metabolites produced under iron limitation kill pinewood nematode and attract Caenorhabditis elegans. Frontiers in Microbiology, 10:2166. Available at: https://doi.org/10.3389/fmicb.2019.02166.
  67. Pulavarty, A., Egan, A., Karpinska, A., Horgan, K., and Kakouli-Duarte, T. 2021. Plant Parasitic nematodes: a review on their behavior, host interaction, management approaches and their occurrence in two sites in the Republic of Ireland. Plants, 10(11):2352. Available at: https://doi.org/10.3390/plants10112352.
  68. Raio, A. 2024. Diverse roles played by ‘Pseudomonas fluorescens complex’ volatile compounds in their interaction with phytopathogenic microorganisms, pests and plants. World Journal of Microbiology and Biotechnology, 40(3):80. Available at: https://doi.org/10.1007/s11274-023-03873-0.
  69. Roberts, A. G. 2014. Plant viruses: soil‐borne, in Wiley, Encyclopedia of Life Sciences, 1st ed, Wiley. Available at: https://doi.org/10.1002/9780470015902.a0000761.pub3.
  70. Runyon, J. B., Mescher, M. C., and De Moraes, C. M. 2006. Volatile chemical cues guide host location and host selection by parasitic plants. Science, 313(5795):1964–1967. Available at: https://doi.org/10.1126/science.1131371.
  71. Sasser, J. N. 1977. Worldwide dissemination and importance of the root-knot nematodes, Meloidogyne spp., J. Nematol., 9(1):26–29.
  72. Sawoszczuk, T., and Syguła-Cholewińska, J. 2017. Application of solid phase microextraction–gas chromatography–mass spectrometry method for the detection of active molds on historical objects. Heritage Science, 5(1):20. Available at: https://doi.org/10.1186/s40494-017-0133-6.
  73. Schulz, S., and Dickschat, J. S. 2007. Bacterial volatiles: the smell of small organisms. Natural Product Reports, 24(4):814. Available at: https://doi.org/10.1039/b507392h.
  74. Sharma, M., and Mallubhotla, S. 2022. Diversity, antimicrobial activity, and antibiotic susceptibility pattern of endophytic bacteria sourced from Cordia dichotoma L. Frontiers in Microbiology, 13:879386. Available at: https://doi.org/10.3389/fmicb.2022.879386.
  75. Snyder, D. W., Opperman, C. H., and Bird, D. M. 2006. A method for generating Meloidogyne incognita males. Journal of Nematology, 38(2):192–194.
  76. Soumare, A., Diedhiou, A. G., Thuita, M., Hafidi, M., Ouhdouch, Y., Gopalakrishnan, S., and et al. 2020) Exploiting biological nitrogen fixation: A route towards a sustainable agriculture. Plants, 9(8):1011. Available at: https://doi.org/10.3390/plants9081011
  77. Stucky, T., Hochstrasser, M., Meyer, S., Segessemann, T., Ruthes, A. C., Ahrens, C. H., et al. 2023. A novel robust screening assay identifies Pseudomonas strains as reliable antagonists of the root-knot nematode Meloidogyne incognita. Microorganisms, 11(8):2011. Available at: https://doi.org/10.3390/microorganisms11082011.
  78. Timper, P., Kone, D., Yin, J., Ji, P., and Gardener, B. B. M. 2009. Evaluation of an antibiotic-producing strain of Pseudomonas fluorescens for suppression of plant-parasitic nematodes. Journal of Nematology, 41(3):234–240.
  79. Tokgöz, S., Lakshman, D. K., Ghozlan, M. H., Pinar, H., Roberts, D. P., and Mitra, A. 2020. Soybean nodule-associated non-rhizobial bacteria inhibit plant pathogens and induce growth promotion in tomato. Plants, 9(11):1494. Available at: https://doi.org/10.3390/plants9111494.
  80. Tóth, F., Bogdányi, F. T., Petrikovszki, R., Gódor, A., Zalai, M., and Sunder, P. 2019. Control of the root-knot nematode Meloidogyne incognita and weeds in protected cucumber with dimethyl disulfide (DMDS) over two crop cycles: The first results in Hungary. Acta Phytopathologica et Entomologica Hungarica, 54(2):267–278. Available at: https://doi.org/10.1556/038.54.2019.026.
  81. Tylka, G. and Mullaney, M. 2021. Soybean cyst nematode-resistant soybean varieties for Iowa, Iowa State University Extension and Outreach. Available at: https://doi.org/10.37578/ONKA5947.
  82. Tylka, G. L., and Marett, C. C. 2021a. Known distribution of the soybean cyst nematode, Heterodera glycines, in the United States and Canada in 2020. Plant Health Progress, 22(1):72–74. Available at: https://doi.org/10.1094/PHP-10-20-0094-BR.
  83. Tylka, G. L., and Marett, C. C. 2021b. Known distribution of the soybean cyst nematode, Heterodera glycines, in the United States and Canada in 2020. Plant Health Progress, 22(1):72–74. Available at: https://doi.org/10.1094/PHP-10-20-0094-BR.
  84. Tylka, G. L., and Marett, C. C. 2025. Known distribution of the soybean cyst nematode, Heterodera glycines, in the United States and Canada Through 2023. Plant Health Progress, 26(1):51–53. Available at: https://doi.org/10.1094/PHP-08-24-0080-RS.
  85. Verma, V. C., and Gange, A. C. (eds.) 2014. Advances in endophytic research, New Delhi: Springer India. Available at: https://doi.org/10.1007/978-81-322-1575-2.
  86. Villari, R., Rubio, M. C., Calvo-Begueria, L., Pérez-Rontomé, C., Larrainzar, E., Wilson, M. T., et al. 2021. Three classes of hemoglobins are required for optimal vegetative and reproductive growth of Lotus japonicus: genetic and biochemical characterization of LjGlb2-1. Journal of Experimental Botany, 72:7778–7791. Available at: https://doi.org/10.1093/jxb/erab376.
  87. Vyas, V., Singh, S., Choudhary, S., Bhoi, T. K., Dey, P., and Saraswat, A. 2025. Pheno-morphological and biochemical characterization of root nodules and associated root nodulating bacteria from Pongamia pinnata (L.) Pierre in the arid regions of India. Frontiers in Plant Science, 16:1717750. Available at: https://doi.org/10.3389/fpls.2025.1717750
  88. Wang, J., Niblack, T. L., Tremain, J. A., Wiebold, W. J., Tylka, G. L., Marett, C. C., et al. 2003. Soybean cyst nematode reduces soybean yield without causing obvious aboveground symptoms. Plant Disease, 87(6):623–628. Available at: https://doi.org/10.1094/PDIS.2003.87.6.623.
  89. Wang, Q., Wang, X., Zhang, D., Fang, W., Li, Y., Cao, A., et al. 2023. Transcriptome reveals the toxicity difference of dimethyl disulfide by contact and fumigation on Meloidogyne incognita through calcium channel-mediated oxidative phosphorylation. Journal of Hazardous Materials, 460:132268. Available at: https://doi.org/10.1016/j.jhazmat.2023.132268.
  90. Winsor, S. 2020. Soybean cyst nematode management in the corn belt. Crops & Soils, 53(4):3–12. Available at: https://doi.org/10.1002/crso.20056.
  91. Wójcik-Gront, E., Gozdowski, D., Derejko, A., and Pudełko, R. 2022. Analysis of the impact of environmental and agronomic variables on agronomic parameters in soybean cultivation based on long-term data. Plants, 11:2922. Available at: https://doi.org/10.3390/plants11212922.
  92. Wu, W., Wang, J., Wang, Z., Yan, X., Wang, Y., and He, X. 2023. Comparative transcriptome analysis reveals the molecular mechanism of Bacillus velezensis GJ-7 assisting Panax notoginseng against Meloidogyne hapla. International Journal of Molecular Sciences, 24(24):17581. Available at: https://doi.org/10.3390/ijms242417581.
  93. Xia, Y., Liu, J., Chen, C., Mo, X., Tan, Q., He, Y., et al. 2022. The multifunctions and future prospects of endophytes and their metabolites in plant disease management. Microorganisms, 10(5):1072. Available at: https://doi.org/10.3390/microorganisms10051072.
  94. Xiang, N., Lawrence, K. S., and Donald, P. A. 2018. Biological control potential of plant growth‐promoting rhizobacteria suppression of Meloidogyne incognita on cotton and Heterodera glycines on soybean: A review. Journal of Phytopathology, 166(7–8):449–458. Available at: https://doi.org/10.1111/jph.12712.
  95. Yan, D., Cao, A., Wang, Q., Li, Y., Canbin, O., Guo, M., and et al. 2019. Dimethyl disulfide (DMDS) as an effective soil fumigant against nematodes in China. PLoS One, 14(10): e0224456. Available at: https://doi.org/10.1371/journal.pone.0224456.
  96. Ye, S., Yan, R., Li, X., Lin, Y., Yang, Z., Ma, Y., and et al. 2022. Biocontrol potential of Pseudomonas rhodesiae GC-7 against the root-knot nematode Meloidogyne graminicola through both antagonistic effects and induced plant resistance. Frontiers in Microbiology, 13:1025727. Available at: https://doi.org/10.3389/fmicb.2022.1025727.
  97. Yigezu Wendimu, G. 2021. Biology, taxonomy, and management of the root-knot nematode (Meloidogyne incognita) in sweet potato. Advances in Agriculture, 2021:1–13. Available at: https://doi.org/10.1155/2021/8820211.
  98. Zhai, Y., Shao, Z., Cai, M., Zheng, L., Li, G., Huang, D., et al. 2018. Multiple modes of nematode control by volatiles of Pseudomonas putida 1A00316 from Antarctic soil against Meloidogyne incognita. Frontiers in Microbiology, 9:253. Available at: https://doi.org/10.3389/fmicb.2018.00253.
  99. Zuhra, K., and Szabo, C. 2022. The two faces of cyanide: an environmental toxin and a potential novel mammalian gasotransmitter. The FEBS Journal, 289(9):2481–2515. Available at: https://doi.org/10.1111/febs.16135.
DOI: https://doi.org/10.2478/jofnem-2026-0030 | Journal eISSN: 2640-396X | Journal ISSN: 0022-300X
Language: English
Page range: 541 - 560
Submitted on: Aug 21, 2025
Accepted on: May 14, 2026
Published on: Oct 19, 2026
Published by: Society of Nematologists, Inc.
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 M. S. Ali, F. T. Z. Mony, M. Evans, S. Rideout, D. Haak, Jonathan D. Eisenback, published by Society of Nematologists, Inc.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.