Role of multimodal imaging in HCM: Thinking beyond fibrosis—A case report

Teodora-Maria Barboi; Ruxandra Oana Jurcut; Sebastian Onciul; Lucian Marius Predescu; Leonard Mandes; Daniela Oana Andrei

doi:10.2478/rjc-2026-0001

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Role of multimodal imaging in HCM: Thinking beyond fibrosis—A case report

Romanian Journal of Cardiology

Volume 36 (2026): Issue 1 (March 2026)

By: Teodora-Maria Barboi, Ruxandra Oana Jurcut, Sebastian Onciul, Lucian Marius Predescu, Leonard Mandes and Daniela Oana Andrei

Open Access

|Feb 2026

Abstract

Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac disorder characterized by diverse phenotypic and genetic expressions, leading to significant clinical complications and increased cardiovascular risk¹. This case focuses on the problematic progression of a 50-year-old woman with non-obstructive HCM and acquired cardiovascular risk factors, culminating in severe systolic dysfunction and the development of an apical aneurysm. Transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) revealed severe left ventricular (LV) systolic dysfunction, alongside significant myocardial fibrosis and viability, which guided prognostic therapeutic decisions, including myocardial revascularization and prophylactic implantable cardioverter-defibrillator (ICD) placement. This case illustrates the importance of using multimodal imaging in managing HCM.

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Articles in this issue

DOI: https://doi.org/10.2478/rjc-2026-0001 | Journal eISSN: 2734-6382 | Journal ISSN: 1220-658X

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Language: English

Page range: 59 - 63

Published on: Feb 6, 2026

Published by: Romanian Society of Cardiology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

hypertrophic cardiomyopathy,

cardiac magnetic resonance,

late gadolinium enhancement,

coronary artery disease,

Related subjects:

Surgery,

Pediatrics and juvenile medicine,

Paediatric cardiology

© 2026 Teodora-Maria Barboi, Ruxandra Oana Jurcut, Sebastian Onciul, Lucian Marius Predescu, Leonard Mandes, Daniela Oana Andrei, published by Romanian Society of Cardiology
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 36 (2026): Issue 1 (March 2026)