Abstract
This study focuses on detecting addictive substances in the human body using modern instrumental methods, specifically the Dräger DrugTest 5000 (DDT 5000) device. Addictive substances are classified by legal status, chemical structure, and patterns of use. The study evaluates various biological matrices for drug detection, identifying oral fluid as the most suitable option due to its non-invasiveness and appropriate detection window. The core objective is to experimentally verify the detection limits of selected substances using the DDT 5000 and compare the findings with the manufacturer’s specifications. Results indicate that most detection limits are below or consistent with those declared by the manufacturer, except for heroin. A notable finding concerns tetrahydrocannabinol (THC), where extremely low and potentially unreliable detection limits were observed, suggesting the need for further verification. In conclusion, the DDT 5000 demonstrates high sensitivity, specificity, and accuracy, making it a reliable tool for rapid detection of most abused substances.