Integrative review of resin-based dental pit and fissure sealants: Composition analysis and a novel categorization proposal

Paweł J. Piszko; Paulina Drapiewska; Julia Kurczyk; Natalia Stelmaszczyk; Michał J. Kulus; Aleksandra Piszko; Maciej Dobrzyński

doi:10.2478/msp-2026-0006

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Integrative review of resin-based dental pit and fissure sealants: Composition analysis and a novel categorization proposal

Materials Science-Poland

Volume 44 (2026): Issue 1 (March 2026)

By: Paweł J. Piszko, Paulina Drapiewska, Julia Kurczyk, Natalia Stelmaszczyk, Michał J. Kulus, Aleksandra Piszko and Maciej Dobrzyński

Open Access

|Apr 2026

Abstract

Introduction

Application of pit and fissure sealants is among the most effective methods of preventing dental caries. Despite their extensive use, the chemical composition of resin-based sealants is ambiguous and inconsistent. The presented integrative review analytically evaluates the composition of commercially available resin-based dental pit and fissure sealants.

Data and sources

Targeted searches were conducted between June 1 and November 15, 2025, using PubMed, ScienceDirect, Scopus, alongside general and academic search engines such as Google Scholar, Google. All relevant website entries were saved using the Internet Archive Wayback Machine platform.

Study selection

Sources providing information on key material components including resin matrix monomers and fillers; grey literature sources and scientific articles published in peer-reviewed journals regarding to the composition of resin-based commercial formulation of dental pit and fissure sealants. Structured data search resulted in identifying 52 formulations of 41 resin-based dental sealants. Among those, 116 unique ingredients were found, of which 41 were assigned a Chemical Abstracts Service number.

Conclusions

Components were classified according to their function into groups. Cluster analysis allowed for the proposal of a new classification of resin-based dental sealants based on their monomer composition. Three distinctive fluoride forms were identified in the analyzed formulations, with each one resulting in different release kinetics and therapeutic effect (fluoride salts, fluoride glass-ionomer fillers, and fluorinated monomers).

Clinical significance

The article highlights the significance and clinical importance of each group of identified compounds and aims to increase awareness of the correlation of composition with clinical properties.

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Articles in this issue

DOI: https://doi.org/10.2478/msp-2026-0006 | Journal eISSN: 2083-134X | Journal ISSN: 2083-1331

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Language: English

Page range: 83 - 107

Submitted on: Feb 5, 2026

Accepted on: Mar 29, 2026

Published on: Apr 22, 2026

Published by: Wroclaw University of Science and Technology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

Dental sealants,

Dental sealants formulations,

Composition analysis,

Related subjects:

Materials sciences, other,

Nanomaterials,

Functional and smart materials,

Materials characterization and properties

© 2026 Paweł J. Piszko, Paulina Drapiewska, Julia Kurczyk, Natalia Stelmaszczyk, Michał J. Kulus, Aleksandra Piszko, Maciej Dobrzyński, published by Wroclaw University of Science and Technology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 44 (2026): Issue 1 (March 2026)