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Forgotten Vaccine Creators and Epidemic Conquerors: Rudolf Weigl and Waldemar Haffkine Cover

Forgotten Vaccine Creators and Epidemic Conquerors: Rudolf Weigl and Waldemar Haffkine

Open Access
|Oct 2026

Figures & Tables

Rudolf Stefan Jan Weigl

Date of birth: September 2, 1883

Place of birth: Přerov, Austro-Hungarian Empire Date of death: August 11, 1957

Place of death: Zakopane, Poland

Nationality: Polish

Field: microbiology, immunology, epidemiology

Key scientific achievement: Development of the first successful typhus vaccine

Table 1.

Selected key publications of Rudolf Weigl on epidemic typhus, Rickettsia prowazekii, and immunization

YearPublicationJournal / SourceMain subject / contribution
1920Weigl, R. Untersuchungen und Experimente an Fleckfieberläusen. Die Technik der Rikettsia-Forschung.Beiträge zur Klinik der Infektionsk-rankheitenExperimental studies on typhus lice and the development of techniques for Rickettsia research
1924Weigl, R. Der gegenwärtige Stand der Rickettsia-Forschung.Klinische WochenschriftReview of the contemporary state of Rickettsia research
1930aWeigl, R. Über das Wesen und die Form des Fleckfiebererregers.Bulletin de l’Académie Polonaise des Sciences et des Lettres, Classe MédicaleResearch on the nature and morphology of the epidemic typhus pathogen
1930bWeigl, R. Die Methoden der aktiven Fleckfieber-Immunisierung.Bulletin de l’Académie Polonaise des Sciences et des Lettres, Classe MédicaleMethods of active immunization against epidemic typhus
1947Weigl, R. Immunization against typhus fever in Poland during World War II.Texas Reports on Biology and MedicineExperience with typhus immunization in Poland during World War II

Waldemar Mordecai Wolff Haffkine

Date of birth: March 15, 1860

Place of birth: Odessa, Russian Empire (now Ukraine) Date of death: October 26, 1930

Place of death: Lausanne, Switzerland

Nationality: Russian (later naturalized British subject) Field: microbiology, immunology, epidemiology

Key scientific achievements: cholera vaccine – 1892; plague vaccine – 1897; mass vaccination methods

Table 2.

Selected key publications of Waldemar Haffkine on cholera and plague vaccination

YearPublicationJournal / SourceMain subject / contribution
1892Haffkine, W. M. On Prophylactic Inoculation Against Cholera.British Medical JournalExperimental development and application of prophylactic inoculation against cholera
1895Haffkine, W. M. Anti-cholera Inoculation: Report to the Government of India.Calcutta: Thacker, Spink & Co.Report on the development and application of anti-cholera inoculation in India
1896Haffkine, W. M. Prophylactic Vaccination Against Bubonic Plague in India.James Lind Library archiveReport on prophylactic plague vaccination, including self-inoculation and experimental studies in rabbits
1897Haffkine, W. M. On the Anti-Plague Vaccine.The LancetDescription of the anti-plague vaccine and its application in the prevention of bubonic plague
1905Haffkine, W. M. Report on a Series of 484 Cases of Plague Treated with Lustig’s Anti-Plague Serum.In: Bannerman, W. B. (ed.), Serum-therapy of Plague in India. Scientific Memoirs by Officers of the Medical and Sanitary Departments of the Government of India. Calcutta: Office of the Superintendent of Government PrintingReport on clinical experience with anti-plague serum in 484 cases of plague
DOI: https://doi.org/10.2478/am-2026-0010 | Journal eISSN: 2545-3149 | Journal ISSN: 0079-4252
Language: English, Polish
Page range: 120 - 126
Submitted on: Nov 8, 2025
Accepted on: Aug 31, 2026
Published on: Oct 13, 2026
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Janusz Marcinkiewicz, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.