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Effectiveness of Neural Mobilizations Techniques on Diabetic Peripheral Neuropathies: A Systematic Review Cover

Effectiveness of Neural Mobilizations Techniques on Diabetic Peripheral Neuropathies: A Systematic Review

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Open Access
|May 2026

Abstract

Background and Objective

Rehabilitation medicine has advanced significantly due to improvements in policy, funding, and technology. Conventional neurorehabilitation, which focuses on high-intensity and task-specific practice, has proven effective in enhancing the performance of neurological patients. Peripheral neuropathy, affecting 25–50% of diabetics particularly those with type 2 diabetes results in damage to nerve fibers, leading to altered motor and sensory functions. Neural mobilization techniques can help restore physiological functions by reducing nerve stress and improving axonal transport and blood flow. This study aims to evaluate the efficacy and safety of these techniques in treating diabetic peripheral neuropathy.

Methodology

The methodology of this systematic review will be based on PRISMA guidelines, since the primary goal of this effort is to mapout all of the research that is currently available on neural mobilization techniques according to inclusion/exclusion criteria. The data will be collected from Pedro, PubMed, Google scholar and Cochrane library, Embase, Base and Science direct.

Discussion

The purpose of this systematic review was to assess how well neural mobilization (NM) techniques can help patients with diabetic peripheral neuropathy (DPN) recover from their condition. Four randomized controlled trials (RCTs) that were published between 2011 and 2024 and satisfied the predetermined inclusion criteria based on methodological quality and relevance to the research question were included in the review.

Conclusion and Results

Neural mobilization methods can help patients with diabetic peripheral neuropathy by lowering pain, enhancing nerve conduction, and improving mobility and balance. Combining NM with conventional rehabilitation programs yielded the biggest benefits.

DOI: https://doi.org/10.2478/ajon-2026-0004 | Journal eISSN: 2208-6781 | Journal ISSN: 1032-335X
Language: English
Page range: 22 - 34
Published on: May 18, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2026 Asad Anwar, Marium Zafar, Aqsa Saman, published by Australasian Neuroscience Nurses Association
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.