References
- Pavlova NN, Thompson CB. The emerging hallmarks of cancer metabolism. Cell metabolism. 2016; 23(1): 27–47. DOI: 10.1016/j.cmet.2015.12.006
- Yang J, Liu F, Wang Y, Qu L, Lin A. LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling. Cancer Letters. 2022; 543: 215798. DOI: 10.1016/j.canlet.2022.215798
- Zhang Y, Mao Q, Xia Q, Cheng J, Huang Z, Li Y, Chen P, Yang J, Fan X, Liang Y, et al. Noncoding RNAs link metabolic reprogramming to immune microenvironment in cancers. Journal of hematology & oncology. 2021; 14(1): 169. DOI: 10.1186/s13045-021-01179-y
- Mondal P, Meeran SM. Long non-coding RNAs in breast cancer metastasis. Non-coding RNA research. 2020; 5(4): 208–218. DOI: 10.1016/j.ncrna.2020.11.004
- Nadhan R, Isidoro C, Song YS, Dhanasekaran DN. Signaling by LncRNAs: Structure, Cellular Homeostasis, and Disease Pathology. Cells. 2022; 11(16): 2517. DOI: 10.3390/cells11162517
- Nadhan R, Dhanasekaran DN. Decoding the Oncogenic Signals from the Long Non-Coding RNAs. Onco. 2021; 1(2): 176–206. DOI: 10.3390/onco1020014
- Fadaka A, Ajiboye B, Ojo O, Adewale O, Olayide I, Emuowhochere R. Biology of glucose metabolization in cancer cells. Journal of Oncological Sciences. 2017; 3(2): 45–51. DOI: 10.1016/j.jons.2017.06.002
- Warburg O. On the origin of cancer cells. Science. 1956; 123(3191): 309–314. DOI: 10.1126/science.123.3191.309
- Jiang B. Aerobic glycolysis and high level of lactate in cancer metabolism and microenvironment. Genes & diseases. 2017; 4(1): 25–27. DOI: 10.1016/j.gendis.2017.02.003
- Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. science. 2009; 324(5930): 1029–1033. DOI: 10.1126/science.1160809
- Li Y, Li H, Wang W, Yu X, Xu Q. LINC00346 regulates glycolysis by modulation of glucose transporter 1 in breast cancer cells. Molecular and cellular probes. 2020; 54: 101667. DOI: 10.1016/j.mcp.2020.101667
- Ellis BC, Graham LD, Molloy PL. CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research. 2014; 1843(2): 372–386. DOI: 10.1016/j.bbamcr.2013.10.016
- Li X, Zhao Q, Qi J, Wang W, Zhang D, Li Z, Qin C. lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma. International journal of oncology. 2018; 53(2): 551–566. DOI: 10.3892/ijo.2018.4418
- Yang F, Zhang H, Mei Y, Wu M. Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect. Molecular cell. 2014; 53(1): 88–100. DOI: 10.1016/j.molcel.2013.11.004
- Hung CL, Wang LY, Yu YL, Chen HW, Srivastava S, Petrovics G, Kung HJ. A long noncoding RNA connects c-Myc to tumor metabolism. Proceedings of the National Academy of Sciences of the United States of America. 2014; 111(52): 18697–18702. DOI: 10.1073/pnas.1415669112
- Wei S, Fan Q, Yang L, Zhang X, Ma Y, Zong Z, Hua X, Su D, Sun H, Li H. Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling. Oncology Reports. 2017; 38(3): 1902–1908. DOI: 10.3892/or.2017.5840
- Wang Y, Zhang X, Wang Z, Hu Q, Wu J, Li Y, Ren X, Wu T, Tao X, Chen X, et al. LncRNA-p23154 promotes the invasion-metastasis potential of oral squamous cell carcinoma by regulating Glut1-mediated glycolysis. Cancer Letters. 2018; 434: 172–183. DOI: 10.1016/j.canlet.2018.07.016
- Cheng Z, Luo C, Guo Z. LncRNA-XIST/microRNA-126 sponge mediates cell proliferation and glucose metabolism through the IRS1/PI3K/Akt pathway in glioma. J Cell Biochem. 2020; 121(3): 2170–2183. DOI: 10.1002/jcb.29440
- Shi J, Zhang Y, Qin B, Wang Y, Zhu X. Long non-coding RNA LINC00174 promotes glycolysis and tumor progression by regulating miR-152-3p/SLC2A1 axis in glioma. Journal of experimental & clinical cancer research: CR. 2019; 38(1): 395. DOI: 10.1186/s13046-019-1390-x
- Zhang H, Qin D, Jiang Z, Zhang J. SNHG9/miR-199a-5p/Wnt2 Axis Regulates Cell Growth and Aerobic Glycolysis in Glioblastoma. Journal of neuropathology and experimental neurology. 2019; 78(10): 939–948. DOI: 10.1093/jnen/nlz078
- Li X, Liu L, Luo Y, Cui S, Chen W, Zeng A, Shi Y, Luo L. Long non-coding RNA SNHG5 promotes glioma progression via miR-205/E2F3 axis. Biosci Rep. 2019; 39(7). DOI: 10.1042/BSR20190668
- Liu L, Shi Y, Shi J, Wang H, Sheng Y, Jiang Q, Chen H, Li X, Dong J. The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression. Cell Death Dis. 2019; 10(6): 463. DOI: 10.1038/s41419-019-1698-7
- Lin YH, Wu MH, Huang YH, Yeh CT, Cheng ML, Chi HC, Tsai CY, Chung IH, Chen CY, Lin KH. Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma. Hepatology. 2018; 67(1): 188–203. DOI: 10.1002/hep.29462
- Chen J, Yu Y, Li H, Hu Q, Chen X, He Y, Xue C, Ren F, Ren Z, Li J, et al. Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer. Molecular Cancer. 2019; 18(1): 33. DOI: 10.1186/s12943-019-0947-9
- Shi J, Wang H, Feng W, Huang S, An J, Qiu Y, Wu K. Long non-coding RNA HOTTIP promotes hypoxia-induced glycolysis through targeting miR-615-3p/HMGB3 axis in non-small cell lung cancer cells. European Journal of Pharmacology. 2019; 862: 172615. DOI: 10.1016/j.ejphar.2019.172615
- Han X, Yang Y, Sun Y, Qin L, Yang Y. LncRNA TUG1 affects cell viability by regulating glycolysis in osteosarcoma cells. Gene. 2018; 674: 87–92. DOI: 10.1016/j.gene.2018.06.085
- Li Z, Li X, Wu S, Xue M, Chen W. Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR–STAT3/microRNA143 pathway. Cancer Science. 2014; 105(8): 951–955. DOI: 10.1111/cas.12461
- Liu HE, Shi HH, Luo XJ. Upregulated Long Noncoding RNA UCA1 Enhances Warburg Effect via miR-203/HK2 Axis in Esophagal Cancer. J Oncol. 2020; 2020: 8847687. DOI: 10.1155/2020/8847687
- Fan L, Huang C, Li J, Gao T, Lin Z, Yao T. Long non-coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer. International journal of molecular medicine. 2018; 42(4): 2247–2259. DOI: 10.3892/ijmm.2018.3778
- Li C, Wang P, Du J, Chen J, Liu W, Ye K. LncRNA RAD51-AS1/miR-29b/c-3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer. IUBMB life. 2021; 73(1): 286–298. DOI: 10.1002/iub.2427
- Li S, Zhu K, Liu L, Gu J, Niu H, Guo J. lncARSR sponges miR-34a-5p to promote colorectal cancer invasion and metastasis via hexokinase-1-mediated glycolysis. Cancer Science. 2020; 111(10): 3938–3952. DOI: 10.1111/cas.14617
- Hu M, Fu Q, Jing C, Zhang X, Qin T, Pan Y. LncRNA HOTAIR knockdown inhibits glycolysis by regulating miR-130a-3p/HIF1A in hepatocellular carcinoma under hypoxia. Biomedicine & Pharmacotherapy. 2020; 125: 109703. DOI: 10.1016/j.biopha.2019.109703
- Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs Rebecca A, Pradeep S, Wu Sherry Y, Ivan C, Ferracin M, Dennison Jennifer B, et al. Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. Cell Reports. 2015; 13(11): 2395–2402. DOI: 10.1016/j.celrep.2015.11.047
- Shen Y, Xu J, Pan X, Zhang Y, Weng Y, Zhou D, He S. LncRNA KCNQ1OT1 sponges miR-34c-5p to promote osteosarcoma growth via ALDOA enhanced aerobic glycolysis. Cell Death Dis. 2020; 11(4): 278. DOI: 10.1038/s41419-020-2485-1
- Xing Z, Zhang Y, Liang K, Yan L, Xiang Y, Li C, Hu Q, Jin F, Putluri V, Putluri N, et al. Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer. Cancer research. 2018; 78(16): 4524–4532. DOI: 10.1158/0008-5472.CAN-17-0385
- Zheng X, Han H, Liu GP, Ma YX, Pan RL, Sang LJ, Li RH, Yang LJ, Marks JR, Wang W, et al. LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. The EMBO journal. 2017; 36(22): 3325–3335. DOI: 10.15252/embj.201797609
- Hong J, Guo F, Lu S-Y, Shen C, Ma D, Zhang X, Xie Y, Yan T, Yu T, Sun T. F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer. Gut. 2021; 70(11): 2123–2137. DOI: 10.1136/gutjnl-2020-322780
- Bian Z, Zhang J, Li M, Feng Y, Wang X, Zhang J, Yao S, Jin G, Du J, Han W. LncRNA–FEZF1-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 SignalingOncogenic Function of FEZF1-AS1 in Colorectal Cancer. Clinical Cancer Research. 2018; 24(19): 4808–4819. DOI: 10.1158/1078-0432.CCR-17-2967
- Zheng X, Zhou Y, Chen W, Chen L, Lu J, He F, Li X, Zhao L. Ginsenoside 20(S)-Rg3 Prevents PKM2-Targeting miR-324-5p from H19 Sponging to Antagonize the Warburg Effect in Ovarian Cancer Cells. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology. 2018; 51(3): 1340–1353. DOI: 10.1159/000495552
- Hua Q, Mi B, Xu F, Wen J, Zhao L, Liu J, Huang G. Hypoxia-induced lncRNA-AC020978 promotes proliferation and glycolytic metabolism of non-small cell lung cancer by regulating PKM2/HIF-1α axis. Theranostics. 2020; 10(11): 4762–4778. DOI: 10.7150/thno.43839
- Zheng Y-L, Li L, Jia Y-X, Zhang B-Z, Li J-C, Zhu Y-H, Li M-Q, He J-Z, Zeng T-T, Ban X-J. LINC01554-mediated glucose metabolism reprogramming suppresses tumorigenicity in hepatocellular carcinoma via downregulating PKM2 expression and inhibiting Akt/mTOR signaling pathway. Theranostics. 2019; 9(3): 796. DOI: 10.7150/thno.28992
- Lang N, Wang C, Zhao J, Shi F, Wu T, Cao H. Long non-coding RNA BCYRN1 promotes glycolysis and tumor progression by regulating the miR-149/PKM2 axis in non-small-cell lung cancer. Mol Med Rep. 2020; 21(3): 1509–1516. DOI: 10.3892/mmr.2020.10944
- Malakar P, Stein I, Saragovi A, Winkler R, Stern-Ginossar N, Berger M, Pikarsky E, Karni R. Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2LncRNA RNA MALAT1 Regulates Cancer Glucose Metabolism. Cancer research. 2019; 79(10): 2480–2493. DOI: 10.1158/0008-5472.CAN-18-1432
- Liang Y, Zhang D, Zheng T, Yang G, Wang J, Meng F, Liu Y, Zhang G, Zhang L, Han J. lncRNA-SOX2OT promotes hepatocellular carcinoma invasion and metastasis through miR-122-5p-mediated activation of PKM2. Oncogenesis. 2020; 9(5): 1–12. DOI: 10.1038/s41389-020-0242-z
- Qian Y, Song W, Wu X, Hou G, Wang H, Hang X, Xia T: DLX6 Antisense RNA 1 Modulates Glucose Metabolism and Cell Growth in Gastric Cancer by Targeting microRNA-4290. Digestive Diseases and Sciences. 2021; 66(2): 460–473. DOI: 10.1007/s10620-020-06223-4
- Tang J, Yan T, Bao Y, Shen C, Yu C, Zhu X, Tian X, Guo F, Liang Q, Liu Q. LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc. Nature communications. 2019; 10(1): 1–15. DOI: 10.1038/s41467-019-11447-8
- Feng J, Ma J, Liu S, Wang J, Chen Y. A noncoding RNA LINC00504 interacts with c-Myc to regulate tumor metabolism in colon cancer. Journal of cellular biochemistry. 2019; 120(9): 14725–14734. DOI: 10.1002/jcb.28733
- Hu R, Zhong P, Xiong L, Duan L. Long Noncoding RNA Cancer Susceptibility Candidate 8 Suppresses the Proliferation of Bladder Cancer Cells via Regulating Glycolysis. DNA and cell biology. 2017; 36(9): 767–774. DOI: 10.1089/dna.2017.3785
- Sun LY, Li XJ, Sun YM, Huang W, Fang K, Han C, Chen ZH, Luo XQ, Chen YQ, Wang WT. LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1. Mol Cancer. 2018; 17(1): 127. DOI: 10.1186/s12943-018-0879-9
- Zou ZW, Ma C, Medoro L, Chen L, Wang B, Gupta R, Liu T, Yang XZ, Chen TT, Wang RZ, et al. LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells. Oncotarget. 2016; 7(38): 61741–61754. DOI: 10.18632/oncotarget.11437
- Shi J, Dai R, Chen Y, Guo H, Han Y, Zhang Y. LncRNA LINP1 regulates acute myeloid leukemia progression via HNF4α/AMPK/WNT5A signaling pathway. Hematological oncology. 2019; 37(4): 474–482. DOI: 10.1002/hon.2651
- Zhou Y, Huang Y, Hu K, Zhang Z, Yang J, Wang Z. HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p. Cell death & disease. 2020; 11(3): 1–14. DOI: 10.1038/s41419-020-2366-7
- Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, Wang C, Hawke DH, Wang S, Zhang Y, et al. The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. Nature cell biology. 2016; 18(2): 213–224. DOI: 10.1038/ncb3295
- Yang B, Zhang L, Cao Y, Chen S, Cao J, Wu D, Chen J, Xiong H, Pan Z, Qiu F. Overexpression of lncRNA IGFBP4–1 reprograms energy metabolism to promote lung cancer progression. Molecular cancer. 2017; 16(1): 1–14. DOI: 10.1186/s12943-017-0722-8
- Wang Y, Lu J-H, Wu Q-N, Jin Y, Wang D-S, Chen Y-X, Liu J, Luo X-J, Meng Q, Pu H-Y. LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer. Molecular cancer. 2019; 18(1): 1–18. DOI: 10.1186/s12943-019-1105-0
- Xiao Z-D, Han L, Lee H, Zhuang L, Zhang Y, Baddour J, Nagrath D, Wood CG, Gu J, Wu X. Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development. Nature communications. 2017; 8(1): 1–13. DOI: 10.1038/s41467-017-00902-z
- Zhang X, Wang S, Wang H, Cao J, Huang X, Chen Z, Xu P, Sun G, Xu J, Lv J, et al. Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway. Molecular Cancer. 2019; 18(1): 20. DOI: 10.1186/s12943-018-0935-5
- Liu D, Li H. Long non-coding RNA GEHT1 promoted the proliferation of ovarian cancer cells via modulating the protein stability of HIF1α. Bioscience Reports. 2019; 39(5). DOI: 10.1042/BSR20181650
- Jing C, Ma R, Cao H, Wang Z, Liu S, Chen D, Wu Y, Zhang J, Wu J. Long noncoding RNA and mRNA profiling in cetuximab-resistant colorectal cancer cells by RNA sequencing analysis. Cancer medicine. 2019; 8(4): 1641–1651. DOI: 10.1002/cam4.2004
- Wan T, Zheng J, Yao R, Yang S, Zheng W, Zhou P. LncRNA DDX11-AS1 accelerates hepatocellular carcinoma progression via the miR-195-5p/MACC1 pathway. Annals of Hepatology. 2021; 20: 100258. DOI: 10.1016/j.aohep.2020.09.003
- Li W, Huang K, Wen F, Cui G, Guo H, He Z, Zhao S. LINC00184 silencing inhibits glycolysis and restores mitochondrial oxidative phosphorylation in esophageal cancer through demethylation of PTEN. EBioMedicine. 2019; 44: 298–310. DOI: 10.1016/j.ebiom.2019.05.055
- Yang X, Ye H, He M, Zhou X, Sun N, Guo W, Lin X, Huang H, Lin Y, Yao R, et al. LncRNA PDIA3P interacts with c-Myc to regulate cell proliferation via induction of pentose phosphate pathway in multiple myeloma. Biochem Biophys Res Commun. 2018; 498(1): 207–213. DOI: 10.1016/j.bbrc.2018.02.211
- Zheng Z-Q, Li Z-X, Guan J-L, Liu X, Li J-Y, Chen Y, Lin L, Kou J, Lv J-W, Zhang L-L. Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance TINCR Promotes Cancer Progression and Chemoresistance. Cancer research. 2020; 80(23): 5174–5188. DOI: 10.1158/0008-5472.CAN-19-3626
- Zhang G, Wang Q, Lu J, Ma G, Ge Y, Chu H, Du M, Wang M, Zhang Z. Long non-coding RNA FLJ22763 is involved in the progression and prognosis of gastric cancer. Gene. 2019; 693: 84–91. DOI: 10.1016/j.gene.2019.01.028
- Tang Y, Tang R, Tang M, Huang P, Liao Z, Zhou J, Zhou L, Su M, Chen P, Jiang J. LncRNA DNAJC3-AS1 regulates fatty acid synthase via the EGFR pathway to promote the progression of colorectal cancer. Frontiers in oncology. 2021; 10: 604534. DOI: 10.3389/fonc.2020.604534
- Wang C, Meng X, Zhou Y, Yu J, Li Q, Liao Z, Gu Y, Han J, Linghu S, Jiao Z, et al. Long Noncoding RNA CTD-2245E15.3 Promotes Anabolic Enzymes ACC1 and PC to Support Non-Small Cell Lung Cancer Growth. Cancer research. 2021; 81(13): 3509–3524. DOI: 10.1158/0008-5472.CAN-19-3806
- Zhou Q, Chen F, Zhao J, Li B, Liang Y, Pan W, Zhang S, Wang X, Zheng D. Long non-coding RNA PVT1 promotes osteosarcoma development by acting as a molecular sponge to regulate miR-195. Oncotarget. 2016; 7(50): 82620. DOI: 10.18632/oncotarget.13012
- Ma D, Yuan L, Lin L. LncRNA HOTAIR contributes to the tumorigenesis of nasopharyngeal carcinoma via up-regulating FASN. Eur Rev Med Pharmacol Sci. 2017; 21(22): 5143–5152.
- Lu C, Ma J, Cai D. Increased HAGLR expression promotes non–small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis. Tumor Biology. 2017; 39(4): 1010428317697574. DOI: 10.1177/1010428317697574
- Christensen LL, True K, Hamilton MP, Nielsen MM, Damas ND, Damgaard CK, Ongen H, Dermitzakis E, Bramsen JB, Pedersen JS, et al. SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism. Molecular Oncology. 2016; 10(8): 1266–1282. DOI: 10.1016/j.molonc.2016.06.003
- Guo J, Fang W, Sun L, Lu Y, Dou L, Huang X, Tang W, Yu L, Li J. Ultraconserved element uc. 372 drives hepatic lipid accumulation by suppressing miR-195/miR4668 maturation. Nature communications. 2018; 9(1): 1–15. DOI: 10.1038/s41467-018-03072-8
- Taniue K, Kurimoto A, Sugimasa H, Nasu E, Takeda Y, Iwasaki K, Nagashima T, Okada-Hatakeyama M, Oyama M, Kozuka-Hata H. Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1. Proceedings of the National Academy of Sciences. 2016; 113(5): 1273–1278. DOI: 10.1073/pnas.1500992113
- Shang C, Wang W, Liao Y, Chen Y, Liu T, Du Q, Huang J, Liang Y, Liu J, Zhao Y. LNMICC Promotes Nodal Metastasis of Cervical Cancer by Reprogramming Fatty Acid MetabolismLNMICC Promotes Lymph Node Metastasis in Cervical Cancer. Cancer research. 2018; 78(4): 877–890. DOI: 10.1158/0008-5472.CAN-17-2356
- Cui M, Xiao Z, Wang Y, Zheng M, Song T, Cai X, Sun B, Ye L, Zhang X. Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9–Mediated RXRA Signaling PathwayLncRNA HULC Facilitates Abnormal Lipid Metabolism in HCC. Cancer research. 2015; 75(5): 846–857. DOI: 10.1158/0008-5472.CAN-14-1192
- Guo L, Lu J, Gao J, Li M, Wang H, Zhan X. The function of SNHG7/miR-449a/ACSL1 axis in thyroid cancer. Journal of Cellular Biochemistry. 2020; 121(10): 4034–4042. DOI: 10.1002/jcb.29569
- Jiang X, Guo S, Zhang Y, Zhao Y, Li X, Jia Y, Xu Y, Ma B. LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p. Cellular signalling. 2020; 65: 109422. DOI: 10.1016/j.cellsig.2019.109422
- Wu H, Liu B, Chen Z, Li G, Zhang Z. MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer. Cell Death & Disease. 2020; 11(4): 233. DOI: 10.1038/s41419-020-2426-z
- He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, et al. MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer. Oncogene. 2019; 38(23): 4637–4654. DOI: 10.1038/s41388-019-0747-0
- Han J, Qu H, Han M, Ding Y, Xie M, Hu J, Chen Y, Dong H. MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer. Oncogene. 2021; 40(4): 833–847. DOI: 10.1038/s41388-020-01574-8
- Xiong Y, Liu Z, Li Z, Wang S, Shen N, Xin Y, Huang T. Long non-coding RNA nuclear paraspeckle assembly transcript 1 interacts with microRNA-107 to modulate breast cancer growth and metastasis by targeting carnitine palmitoyltransferase-1. International Journal of Oncology. 2019; 55(5): 1125–1136. DOI: 10.3892/ijo.2019.4869
- Liu C, Yang Z, Wu J, Zhang L, Lee S, Shin DJ, Tran M, Wang L. Long noncoding RNA H19 interacts with polypyrimidine tract-binding protein 1 to reprogram hepatic lipid homeostasis. Hepatology. 2018; 67(5): 1768–1783. DOI: 10.1002/hep.29654
- Yan C, Chen J, Chen N. Long noncoding RNA MALAT1 promotes hepatic steatosis and insulin resistance by increasing nuclear SREBP-1c protein stability. Scientific reports. 2016; 6(1): 1–11. DOI: 10.1038/srep22640
- Li D, Cheng M, Niu Y, Chi X, Liu X, Fan J, Fan H, Chang Y, Yang W. Identification of a novel human long non-coding RNA that regulates hepatic lipid metabolism by inhibiting SREBP-1c. International journal of biological sciences. 2017; 13(3): 349. DOI: 10.7150/ijbs.16635
- Yang L, Li P, Yang W, Ruan X, Kiesewetter K, Zhu J, Cao H. Integrative transcriptome analyses of metabolic responses in mice define pivotal LncRNA metabolic regulators. Cell metabolism. 2016; 24(4): 627–639. DOI: 10.1016/j.cmet.2016.08.019
- Liu G, Zheng X, Xu Y, Lu J, Chen J, Huang X. Long non-coding RNAs expression profile in HepG2 cells reveals the potential role of long non-coding RNAs in the cholesterol metabolism. Chinese Medical Journal. 2015; 128(01): 91–97. DOI: 10.4103/0366-6999.147824
- Yu Y, Dong JT, He B, Zou YF, Li XS, Xi CH, Yu Y. LncRNA SNHG16 induces the SREBP2 to promote lipogenesis and enhance the progression of pancreatic cancer. Future oncology (London, England). 2019; 15(33): 3831–3844. DOI: 10.2217/fon-2019-0321
- Qin Y, Hou Y, Liu S, Zhu P, Wan X, Zhao M, Peng M, Zeng H, Li Q, Jin T. A Novel Long Non-Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis. Advanced Science. 2021; 8(2): 2002232. DOI: 10.1002/advs.202002232
- Wang L, Lin C, Sun N, Wang Q, Ding X, Sun Y. Long non-coding RNA CASC19 facilitates non-small cell lung cancer cell proliferation and metastasis by targeting the miR-301b-3p/LDLR axis. The Journal of Gene Medicine. 2020; 22(12): e3254. DOI: 10.1002/jgm.3254
- Lan X, Yan J, Ren J, Zhong B, Li J, Li Y, Liu L, Yi J, Sun Q, Yang X. A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism. Hepatology. 2016; 64(1): 58–72. DOI: 10.1002/hep.28391
- Zhang L, Yang Z, Trottier J, Barbier O, Wang L. Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay. Hepatology. 2017; 65(2): 604–615. DOI: 10.1002/hep.28882
- Huang-Fu N, Cheng JS, Wang Y, Li ZW, Wang SH. Neat1 regulates oxidized low-density lipoprotein-induced inflammation and lipid uptake in macrophages via paraspeckle formation. Molecular medicine reports. 2018; 17(2): 3092–3098. DOI: 10.3892/mmr.2017.8211
- Dong X-H, Lu Z-F, Kang C-M, Li X-H, Haworth KE, Ma X, Lu J-B, Liu X-H, Fang F-C, Wang CS. The long noncoding RNA RP11-728F11. 4 promotes atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology. 2021; 41(3): 1191–1204. DOI: 10.1161/ATVBAHA.120.315114
- Li S, Yang S, Qiu C, Sun D. LncRNA MSC-AS1 facilitates lung adenocarcinoma through sponging miR-33b-5p to up-regulate GPAM. Biochemistry and Cell Biology. 2021; 99(2): 241–248. DOI: 10.1139/bcb-2020-0239
- Mazar J, Zhao W, Khalil AM, Lee B, Shelley J, Govindarajan SS, Yamamoto F, Ratnam M, Aftab MN, Collins S, et al. The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells. Oncotarget. 2014; 5(19): 8959–8969. DOI: 10.18632/oncotarget.1863
- Molina E, Chew GS, Myers SA, Clarence EM, Eales JM, Tomaszewski M, Charchar FJ. A novel Y-specific long non-coding RNA associated with cellular lipid accumulation in HepG2 cells and atherosclerosis-related genes. Scientific reports. 2017; 7(1): 1–12. DOI: 10.1038/s41598-017-17165-9
- Li D, Guo L, Deng B, Li M, Yang T, Yang F, Yang Z. Long non-coding RNA HR1 participates in the expression of SREBP-1c through phosphorylation of the PDK1/AKT/FoxO1 pathway. Molecular Medicine Reports. 2018; 18(3): 2850–2856. DOI: 10.3892/mmr.2018.9278
- Liu X, Liang Y, Song R, Yang G, Han J, Lan Y, Pan S, Zhu M, Liu Y, Wang Y. Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation. Molecular cancer. 2018; 17(1): 1–18. DOI: 10.1186/s12943-018-0838-5
- Halley P, Kadakkuzha BM, Faghihi MA, Magistri M, Zeier Z, Khorkova O, Coito C, Hsiao J, Lawrence M, Wahlestedt C. Regulation of the apolipoprotein gene cluster by a long noncoding RNA. Cell reports. 2014; 6(1): 222–230. DOI: 10.1016/j.celrep.2013.12.015
- Bao G, Huang J, Pan W, Li X, Zhou T. Long noncoding RNA CERS6-AS1 functions as a malignancy promoter in breast cancer by binding to IGF2BP3 to enhance the stability of CERS6 mRNA. Cancer medicine. 2020; 9(1): 278–289. DOI: 10.1002/cam4.2675
- Pan Q, Li B, Zhang J, Du X, Gu D. LncRNA THAP9-AS1 accelerates cell growth of esophageal squamous cell carcinoma through sponging miR-335–5p to regulate SGMS2. Pathology-Research and Practice. 2021; 224: 153526. DOI: 10.1016/j.prp.2021.153526
- Yang G, Zhou L, Xu Q, Meng F, Wan Y, Meng X, Wang L, Zhang L. LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis. Cell Cycle. 2020; 19(19): 2519–2529. DOI: 10.1080/15384101.2020.1809259
- Cheng J-L, Li D-J, Lv M-Y, Pei Y-J, Zhang X-J, Li L, Liu X-Y, Fan A-H. LncRNA KCNQ1OT1 regulates the invasion and migration of hepatocellular carcinoma by acting on S1PR1 through miR-149. Cancer gene therapy. 2021; 28(7): 850–863. DOI: 10.1038/s41417-020-0203-x
- Liu B, Zhan X, Liu C. Long Noncoding RNA MALAT1 Interacts with miR-124-3p to Modulate Osteosarcoma Progression by Targeting SphK1. Journal of Oncology. 2021; 2021. DOI: 10.21203/rs.3.rs-254076/v1
- Tang C, Wu Y, Wang X, Chen K, Tang Z, Guo X. LncRNA MAFG-AS1 regulates miR-125b-5p/SphK1 axis to promote the proliferation, migration, and invasion of bladder cancer cells. Human Cell. 2021; 34(2): 588–597. DOI: 10.1007/s13577-020-00470-3
- Postepska-Igielska A, Giwojna A, Gasri-Plotnitsky L, Schmitt N, Dold A, Ginsberg D, Grummt I. LncRNA Khps1 regulates expression of the proto-oncogene SPHK1 via triplex-mediated changes in chromatin structure. Molecular cell. 2015; 60(4): 626–636. DOI: 10.1016/j.molcel.2015.10.001
- Lu Z, Xiao Z, Liu F, Cui M, Li W, Yang Z, Li J, Ye L, Zhang X. Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1). Oncotarget. 2016; 7(1): 241. DOI: 10.18632/oncotarget.6280
- Wang L, Chen X, Sun X, Suo J. Long noncoding RNA LINC00460 facilitates colorectal cancer progression by negatively regulating miR-613. OncoTargets and therapy. 2020; 13: 7555. DOI: 10.2147/OTT.S254489
- Sun Y, Shi T, Ma Y, Qin H, Li K. Long noncoding RNA LINC00520 accelerates progression of papillary thyroid carcinoma by serving as a competing endogenous RNA of microRNA-577 to increase Sphk2 expression. Cell Cycle. 2020; 19(7): 787–800. DOI: 10.1080/15384101.2020.1731062
- Feng L, Yang B, Tang XD. Long noncoding RNA LINC00460 promotes carcinogenesis via sponging miR-613 in papillary thyroid carcinoma. Journal of cellular physiology. 2019; 234(7): 11431–11439. DOI: 10.1002/jcp.27799
- Shi Y, Liu M, Huang Y, Zhang J, Yin L. Promotion of cell autophagy and apoptosis in cervical cancer by inhibition of long noncoding RNA LINC00511 via transcription factor RXRA-regulated PLD1. Journal of cellular physiology. 2020; 235(10): 6592–6604. DOI: 10.1002/jcp.29529
- Xu W, Xu Q, Kuang D, Wang Z, Lu Q, Lin Q, Wu H, Chen L. Long non-coding RNA SLNCR1 regulates non-small cell lung cancer migration, invasion and stemness through interactions with secretory phospholipase A2. Molecular medicine reports. 2019; 20(3): 2591–2596. DOI: 10.3892/mmr.2019.10518
- Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, et al. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. Molecular cell. 2016; 61(4): 520–534. DOI: 10.1016/j.molcel.2016.01.015
- Ge Y, Yan X, Jin Y, Yang X, Yu X, Zhou L, Han S, Yuan Q, Yang M. MiRNA-192 [corrected] and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma. PLoS genetics. 2015; 11(12): e1005726. DOI: 10.1371/journal.pgen.1005726
- Bing ZX, Zhang JQ, Wang GG, Wang YQ, Wang TG, Li DQ. Silencing of circ_0000517 suppresses proliferation, glycolysis, and glutamine decomposition of non-small cell lung cancer by modulating miR-330-5p/YY1 signal pathway. The Kaohsiung journal of medical sciences. 2021; 37(12): 1027–1037. DOI: 10.1002/kjm2.12440
- Yue Q, Xu Y, Deng X, Wang S, Qiu J, Qian B, Zhang Y. Circ-PITX1 Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1248/CCND2 Axis. OncoTargets and therapy. 2021; 14: 1807–1819. DOI: 10.2147/OTT.S286820
- Liu L, Cui S, Wan T, Li X, Tian W, Zhang R, Luo L, Shi Y. Long non-coding RNA HOTAIR acts as a competing endogenous RNA to promote glioma progression by sponging miR-126-5p. Journal of cellular physiology. 2018; 233(9): 6822–6831. DOI: 10.1002/jcp.26432
- Li HJ, Li X, Pang H, Pan JJ, Xie XJ, Chen W. Long non-coding RNA UCA1 promotes glutamine metabolism by targeting miR-16 in human bladder cancer. Japanese journal of clinical oncology. 2015; 45(11): 1055–1063. DOI: 10.1093/jjco/hyv132
- Zhou Q, Zhan H, Lin F, Liu Y, Yang K, Gao Q, Ding M, Liu Y, Huang W, Cai Z. LincRNA-p21 suppresses glutamine catabolism and bladder cancer cell growth through inhibiting glutaminase expression. Bioscience Reports. 2019; 39(4). DOI: 10.1042/BSR20182372
- Luan W, Zhang X, Ruan H, Wang J, Bu X. Long noncoding RNA OIP5-AS1 acts as a competing endogenous RNA to promote glutamine catabolism and malignant melanoma growth by sponging miR-217. Journal of cellular physiology; 2019. DOI: 10.1002/jcp.28335
- Deng SJ, Chen HY, Zeng Z, Deng S, Zhu S, Ye Z, He C, Liu ML, Huang K, Zhong JX, et al. Nutrient Stress-Dysregulated Antisense lncRNA GLS-AS Impairs GLS-Mediated Metabolism and Represses Pancreatic Cancer Progression. Cancer research. 2019; 79(7): 1398–1412. DOI: 10.1158/0008-5472.CAN-18-0419
- Wang R, Cao L, Thorne RF, Zhang XD, Li J, Shao F, Zhang L, Wu M. LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation. Science advances. 2021; 7(13). DOI: 10.1126/sciadv.abe5708
- Zhu X, Han J, Lan H, Lin Q, Wang Y, Sun X. A novel circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 pathway regulates cisplatin-resistance in non-small cell lung cancer (NSCLC). BMC cancer. 2020; 20(1): 1–11. DOI: 10.1186/s12885-020-07680-w
- Guan H, Sun C, Gu Y, Li J, Ji J, Zhu Y. Circular RNA circ_0003028 contributes to tumorigenesis by regulating GOT2 via miR-1298-5p in non-small cell lung cancer. Bioengineered. 2021; 12(1): 2326–2340. DOI: 10.1080/21655979.2021.1935064
- Zeng B, Ye H, Chen J, Cheng D, Cai C, Chen G, Chen X, Xin H, Tang C, Zeng J. LncRNA TUG1 sponges miR-145 to promote cancer progression and regulate glutamine metabolism via Sirt3/GDH axis. Oncotarget. 2017; 8(69): 113650–113661. DOI: 10.18632/oncotarget.21922
- He J, Li F, Zhou Y, Hou X, Liu S, Li X, Zhang Y, Jing X, Yang L. LncRNA XLOC_006390 promotes pancreatic carcinogenesis and glutamate metabolism by stabilizing c-Myc. Cancer Letters. 2020; 469: 419–428. DOI: 10.1016/j.canlet.2019.11.021
- Liao M, Liao W, Xu N, Li B, Liu F, Zhang S, Wang Y, Wang S, Zhu Y, Chen D, et al. LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2. EBioMedicine. 2019; 41: 200–213. DOI: 10.1016/j.ebiom.2019.01.035
- Xue M, Hong W, Jiang J, Zhao F, Gao X. Circular RNA circ-LDLRAD3 serves as an oncogene to promote non-small cell lung cancer progression by upregulating SLC1A5 through sponging miR-137. RNA biology. 2020; 17(12): 1811–1822. DOI: 10.1080/15476286.2020.1789819
- Li H, Chen S, Liu J, Guo X, Xiang X, Dong T, Ran P, Li Q, Zhu B, Zhang X. Long non-coding RNA PVT1-5 promotes cell proliferation by regulating miR-126/SLC7A5 axis in lung cancer. Biochemical and biophysical research communications. 2018; 495(3): 2350–2355. DOI: 10.1016/j.bbrc.2017.12.114
- Wang J, Ding M, Zhu H, Cao Y, Zhao W. Up-regulation of long noncoding RNA MINCR promotes non-small cell of lung cancer growth by negatively regulating miR-126/SLC7A5 axis. Biochemical and biophysical research communications. 2019; 508(3): 780–784. DOI: 10.1016/j.bbrc.2018.11.162
- Yin J, Tu G, Peng M, Zeng H, Wan X, Qiao Y, Qin Y, Liu M, Luo H. GPER-regulated lncRNA-Glu promotes glutamate secretion to enhance cellular invasion and metastasis in triple-negative breast cancer. The FASEB Journal. 2020; 34(3): 4557–4572. DOI: 10.1096/fj.201901384RR
- Zeng J, Li Y, Wang Y, Xie G, Feng Q, Yang Y, Feng J. lncRNA 00312 Attenuates Cell Proliferation and Invasion and Promotes Apoptosis in Renal Cell Carcinoma via miR-34a-5p/ASS1 Axis. Oxidative medicine and cellular longevity. 2020; 2020: 5737289. DOI: 10.1155/2020/5737289
- Yuan J, Liu Z, Song R. Antisense lncRNA As-SLC7A11 suppresses epithelial ovarian cancer progression mainly by targeting SLC7A11. Die Pharmazie-An International Journal of Pharmaceutical Sciences. 2017; 72(7): 402–407.
- Guo T, Wang H, Liu P, Xiao Y, Wu P, Wang Y, Chen B, Zhao Q, Liu Z, Liu Q. SNHG6 Acts as a Genome-Wide Hypomethylation Trigger via Coupling of miR-1297-Mediated S-Adenosylmethionine-Dependent Positive Feedback Loops. Cancer research. 2018; 78(14): 3849–3864. DOI: 10.1158/0008-5472.CAN-17-3833
- Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen P, Weinstock A, Wagner A, et al. Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. Nature cell biology. 2015; 17(12): 1556–1568. DOI: 10.1038/ncb3272
- Nilsson A, Haanstra JR, Engqvist M, Gerding A, Bakker BM, Klingmüller U, Teusink B, Nielsen J. Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 2020; 117(19): 10294–10304. DOI: 10.1073/pnas.1919250117
- Xiao Y, Yurievich UA, Yosypovych SV. Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression. Oncotarget. 2017; 8(47): 83171–83182. DOI: 10.18632/oncotarget.20487
- Wang M, Hu H, Wang Y, Huang Q, Huang R, Chen Y, Ma T, Qiao T, Zhang Q, Wu H, et al. Long non-coding RNA TUG1 mediates 5-fluorouracil resistance by acting as a ceRNA of miR-197-3p in colorectal cancer. Journal of Cancer. 2019; 10(19): 4603–4613. DOI: 10.7150/jca.32065
- Li P, Zhang X, Wang L, Du L, Yang Y, Liu T, Li C, Wang C. lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer. Molecular therapy Nucleic acids. 2017; 8: 356–369. DOI: 10.1016/j.omtn.2017.07.007
- Chen W, Xu XK, Li JL, Kong KK, Li H, Chen C, He J, Wang F, Li P, Ge XS, et al. MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression. Oncotarget. 2017; 8(14): 22783–22799. DOI: 10.18632/oncotarget.15199
- Gandhi M, Groß M, Holler JM, Coggins SA, Patil N, Leupold JH, Munschauer M, Schenone M, Hartigan CR, Allgayer H, et al. The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 – RRM2 axis in cancer. Nature communications. 2020; 11(1): 3214. DOI: 10.1038/s41467-020-17007-9
DOI: https://doi.org/10.55233/1750-2187-16-1 | Journal eISSN: 1750-2187
Language: English
Page range: 1 - 1
Submitted on: Nov 3, 2022
Accepted on: Nov 3, 2022
Published on: Nov 23, 2022
Published by: Danny N. Dhanasekaran
In partnership with: Paradigm Publishing Services
Keywords:
© 2022 Revathy Nadhan, Danny N. Dhanasekaran, published by Danny N. Dhanasekaran
This work is licensed under the Creative Commons Attribution 4.0 License.