Table 1
Mortality rates for AA in individuals aged 55 and older at global and regional levels, along with the associated AAPCs from 1990 to 2021.
| LOCATION | 1990 | 2021 | 1990–2021 | |||
|---|---|---|---|---|---|---|
| CASES (95% UI) | ASMR PER 100,000 (95% UI) | CASES (95% UI) | ASMR PER 100,000 (95% UI) | CASES CHANGE (95% CI) | AACP (95% CI) | |
| Globe | ||||||
| Total | 79607.58 (74397.50–84032.01) | 13.90 (12.74–14.78) | 138450.22 (123753.62–149214.49) | 9.93 (8.69–10.84) | 73.92 (62.85–82.44) | –1.07 (–1.15 to –0.99) |
| Male | 51281.87 (48272.13–55304.78) | 21.31 (19.62–22.98) | 82322.88 (75999.88–89458.15) | 13.61 (12.25–14.90) | 60.53 (51.85–69.91) | –1.45 (–1.54 to –1.36) |
| Female | 28325.71 (25536.14–31234.34) | 8.72 (7.61–9.66) | 56127.33 (47405.49–62050.43) | 7.04 (5.84–7.92) | 98.15 (79.15–113.26) | –0.70 (–0.80 to –0.59) |
| SDI | ||||||
| High SDI | 51071.57 (47779.66–52698.60) | 26.41 (24.48–27.53) | 63673.55 (54171.11–68784.57) | 15.37 (13.21–16.61) | 24.68 (13.49–31.39) | –1.77 (–1.85 to –1.69) |
| High-middle SDI | 15596.83 (14863.36–16247.41) | 10.23 (9.50–10.80) | 30776.97 (28510.43–32911.58) | 9.14 (8.24–9.89) | 97.33 (82.26–111.47) | –0.36 (–0.67 to –0.04) |
| Middle SDI | 6900.25 (6360.25–7667.24) | 5.29 (4.74–5.96) | 24295.67 (22015.17–26392.91) | 5.96 (5.23–6.58) | 252.10 (211.02–290.42) | 0.40 (0.31–0.49) |
| Low-middle SDI | 3794.10 (3001.84–5161.93) | 4.70 (3.66–6.46) | 14323.09 (11893.41–19198.01) | 6.97 (5.68–9.35) | 277.51 (213.93–345.28) | 1.31 (1.20–1.42) |
| Low SDI | 2125.00 (1286.46–3694.07) | 7.33 (4.41–12.70) | 5204.64 (3240.03–8583.43) | 7.94 (4.83–13.05) | 144.92 (100.28–199.32) | 0.28 (0.12–0.43) |
| GBD Regions | ||||||
| Andean Latin America | 156.06 (132.58–185.43) | 5.20 (4.10–6.63) | 460.04 (383.35–551.60) | 4.85 (3.78–6.19) | 194.78 (131.33–277.43) | –0.18 (–0.66 to –0.30) |
| Australasia | 1826.72 (1712.05–1933.55) | 45.36 (39.99–50.39) | 1492.29 (1298.04–1620.05) | 14.45 (12.19–16.35) | –18.31 (–26.43 to –11.80) | –3.67 (–3.94 to –3.41) |
| Caribbean | 855.56 (790.97–913.64) | 21.12 (18.80–23.59) | 1318.58 (1159.34–1476.95) | 14.33 (12.26–16.54) | 54.12 (35.95–73.16) | –1.19 (–1.61 to –0.77) |
| Central Asia | 336.45 (289.44–402.37) | 4.57 (3.88–5.53) | 1234.08 (1095.70–1383.65) | 10.46 (9.13–11.84) | 266.79 (198.04–339.71) | 2.69 (2.28–3.10) |
| Central Europe | 3847.21 (3687.46–3977.96) | 15.84 (14.88–16.67) | 6213.49 (5716.40–6801.20) | 15.40 (13.80–17.11) | 61.51 (49.56–76.63) | –0.21 (–0.59 to –0.17) |
| Central Latin America | 987.94 (942.54–1027.58) | 8.23 (7.51–8.91) | 2908.56 (2525.26–3328.30) | 7.26 (6.12–8.40) | 194.41 (157.08–236.30) | –0.49 (–0.89 to –0.10) |
| Central Sub-Saharan Africa | 400.39 (217.61–667.45) | 14.64 (7.58–25.62) | 856.67 (477.70–1397.99) | 13.02 (6.91–22.07) | 113.96 (61.29–183.37) | –0.38 (–0.45 to –0.31) |
| East Asia | 1849.72 (1512.66–2299.32) | 1.57 (1.28–1.95) | 7699.48 (6220.92–9524.14) | 2.18 (1.74–2.71) | 316.25 (192.52–474.42) | 1.07 (0.88–1.26) |
| Eastern Europe | 5640.40 (5427.65–5884.70) | 12.23 (11.53–12.93) | 11842.32 (10896.40–12763.24) | 18.97 (17.09–20.77) | 109.96 (92.54–126.98) | 1.79 (0.80–2.78) |
| Eastern Sub-Saharan Africa | 911.76 (533.71–1555.47) | 9.68 (5.59–16.50) | 2037.54 (1104.09–3371.79) | 9.54 (5.14–15.69) | 123.47 (66.78–200.84) | –0.03 (–0.14 to –0.08) |
| High-income Asia Pacific | 4894.03 (4516.10–5125.51) | 15.40 (13.92–16.44) | 24857.23 (20020.26–27617.45) | 23.71 (19.61–26.32) | 407.91 (341.50–454.19) | 1.41 (1.25–1.58) |
| High-income North America | 18539.85 (17178.63–19326.41) | 29.24 (26.73–30.79) | 12703.78 (11188.78–13505.33) | 10.48 (9.22–11.27) | –31.48 (–34.98 to –29.10) | –3.29 (–3.61 to –2.98) |
| North Africa and Middle East | 766.43 (573.16–1035.34) | 3.18 (2.19–4.57) | 2932.09 (2522.52–3433.24) | 4.59 (3.66–5.77) | 282.56 (166.76–439.21) | 1.23 (1.03–1.43) |
| Oceania | 37.26 (28.44–49.94) | 11.99 (8.81–16.35) | 87.15 (67.88–110.86) | 10.04 (7.45–13.49) | 133.86 (88.29–194.57) | –0.57 (–0.77 to –0.38) |
| South Asia | 2840.08 (1796.93–4566.73) | 3.77 (2.35–6.08) | 13965.31 (10035.92–20377.61) | 6.57 (4.75–9.57) | 391.72 (267.06–581.29) | 1.85 (1.34–2.36) |
| Southeast Asia | 1738.50 (1397.58–2180.37) | 5.59 (4.37–7.21) | 6540.62 (5719.64–7554.84) | 7.57 (6.20–9.11) | 276.22 (194.00–376.33) | 0.96 (0.84–1.08) |
| Southern Latin America | 1914.56 (1777.46–2074.10) | 25.23 (21.98–28.64) | 2149.33 (1971.42–2315.96) | 14.00 (12.24–15.76) | 12.26 (–0.14–25.04) | –1.82 (–2.01 to –1.62) |
| Southern Sub-Saharan Africa | 586.50 (460.12–706.69) | 16.03 (12.15–20.05) | 995.40 (902.88–1093.07) | 12.71 (10.94–14.66) | 69.72 (41.49–121.68) | –0.77 (–1.04 to –0.49) |
| Tropical Latin America | 2245.90 (2134.43–2334.05) | 16.67 (15.29–17.82) | 8764.08 (7980.25–9279.91) | 20.74 (18.39–22.52) | 290.23 (265.49–310.71) | 0.78 (0.60–0.96) |
| Western Europe | 27754.95 (26032.69–28621.87) | 26.54 (24.69–27.79) | 26510.00 (23076.72–28162.70) | 14.11 (12.39–15.13) | –4.49 (–11.39 to –0.28) | –2.03 (–2.20 to –1.86) |
| Western Sub-Saharan Africa | 1477.30 (780.91–2627.39) | 12.84 (6.64–23.00) | 2882.18 (1444.99–4848.08) | 11.83 (5.90–20.06) | 95.10 (45.92–144.01) | –0.26 (–0.37 to –0.14) |
[i] AA, aortic aneurysm; AAPC, average annual percentage change; ASMR, age-standardized mortality rate; SDI, sociodemographic index; GBD, Global Burden of Disease; UI, uncertainty intervals; CI, confidence interval.
Figure 1
Joinpoint regression analysis of the global ASMR (A) and ASDR (B) for AA in individuals aged 55 and older from 1990 to 2021. ASMR: age-standardized mortality rate; ASDR: age-standardized disability-adjusted life years rate; AA: aortic aneurysm. *indicates that the APC is significantly different from zero at the alpha = 0.05 level.
Figure 2
Global AA deaths and death rates (A), DALYs and DALY rates (B) in 2021, categorized by age and gender. The blue and red lines represent the rates for males and females, respectively, with the shaded area showing the 95% uncertainty intervals. AA: aortic aneurysm; DALYs: disability-adjusted life years.
Figure 3
ASMR (A) and ASDR (B) of AA among individuals aged 55 and older in 204 countries and territories in 2021. ASMR: age-standardized mortality rate; ASDR: age-standardized disability-adjusted life years rate; AA: aortic aneurysm.
Figure 4
ASMR (A) and ASDR (B) of AA among individuals aged 55 and older from 1990 to 2021 across 21 regions classified by SDI. ASMR: age-standardized mortality rate; ASDR: age-standardized disability-adjusted life years rate; AA: aortic aneurysm; SDI: sociodemographic index.
Figure 5
Forecasts for the number of deaths (A), ASMR (B), DALYs (C), and ASDR (D) for AA by 2050. The red solid line represents the projections from 2022 to 2050, with the shaded area indicating the 95% confidence interval. ASMR: age-standardized mortality rate; DALYs: disability-adjusted life years; ASDR: age-standardized disability-adjusted life years rate; AA, aortic aneurysm.