
Neuroleptic malignant syndrome: a fatal case with unusual features
Abstract
Neuroleptic malignant syndrome is a rare, but potentially life threatening, idiosyncratic reaction primarily related to use of neuroleptic medications. We report a fatal case of neuroleptic malignant syndrome in a 67 year old female with bipolar affective disorder, triggered by recent change of medications. She had marked elevation of creatinine phosphokinase levels, thrombocytopenia and acute kidney injury but no muscle rigidity. Despite early detection, intensive care support and continuous renal replacement therapy, the patient died of rhabdomyolysis induced acute kidney injury and persistent metabolic acidosis.
DOI: http://dx.doi.org/10.4038/sljpsyc.v5i2.7823
Sri Lanka Journal of Psychiatry Vol 5(2):35-36
© 2014 U. M. Wariyapperuma, C. I.V. Jayasundera, published by Sri Lanka College of Psychiatrists
This work is licensed under the Creative Commons License.