Influence of musculoskeletal model implemented in the AnyBody Modeling System on calculated loadings acting in the lower extremity during gait
References
- Chrzan, M., Michnik, R., Nowakowska-Lipiec, K., Zadoń, H., Jochymczyk-Woźniak, K., Myśliwiec, A., et al., The influence of isometric rotation of the lower limb on the functioning of the knee joint stabilizers and rotator muscles, Acta. Bioeng. Biomech., 2022, 24(4): 139–146. 10.37190/ABB-02158-2022-01.
- Zadoń, H., Nowakowska-Lipiec, K., Michnik, R., A sitting or standing position – which one exerts more loads on the musculoskeletal system of the lumbar spine? Comparative tests based on the methods of mathematical modelling, Acta. Bioeng. Biomech., 2021, 23(1): 113–120. 10.37190/ABB-01762-2020-01.
- Davico, G., Pizzolato, C., Lloyd, D.G., Obst, S.J., Walsh, H.P.J., Carty, C.P., Increasing level of neuromusculoskeletal model personalisation to investigate joint contact forces in cerebral palsy: a twin case study, Clin. Biomech., 2020, 72: 141–149. 10.1016/j.clinbiomech.2019.12.011.
- Hata, K., Ishido, Y., Fukudome, K., Kiyama, R., Kawada, M., Nishi, T., et al., Effect of alteration in hip joint alignment following total hip arthroplasty on hip joint contact force during gait, Acta. Bioeng. Biomech., 2023, 25(3): 15–24. 10.37190/abb-02284-2023-02.
- Kainz, H., Modenese, L., Lloyd, D.G., Maine, S., Walsh, H.P.J., Carty, C.P., Joint kinematic calculation based on clinical direct kinematic versus inverse kinematic gait models, J. Biomech., 2016, 49: 1658–1669. 10.1016/j.jbiomech.2016.03.052.
- Skubich, J., Analysis of loadings acting in the musculoskeletal system in people with cerebral palsy. PhD Thesis (in polish), Bialystok University of Technology, 2023.
- Skubich, J., Piszczatowski, S., Model of loading acting on the femoral bone during gait, J. Biomech., 2019, 87: 54–63. 10.1016/j.jbiomech.2019.02.018.
- Soodmand, I., Kebbach, M., Ren, X., Bruhn, S., Tischer, T., Bader, R., et al., A musculoskeletal simulation study on the biomechanics of the lower extremity during the golf swing, Acta. Bioeng. Biomech., 2023, 25(3): 177–188. 10.37190/ABB-02316-2023-02.
- Yamagata, M., Taniguchi, M., Tateuchi, H., Kobayashi, M., Ichihashi, N., The effects of knee pain on knee contact force and external knee adduction moment in patients with knee osteoarthritis, J. Biomech., 2021, 123: 110538. 10.1016/j.jbiomech.2021.110538.
- Abdullah, M., Hulleck, A.A., Katmah, R., Khalaf, K., El-Rich, M., Multibody dynamics-based musculoskeletal modeling for gait analysis: a systematic review, J. Neuroeng. Rehabil., 2024, 21: 178. 10.1186/s12984-024-01458-y.
- Jing, Z., Han, J., Zhang, J., Comparison of biomechanical analysis results using different musculoskeletal models for children with cerebral palsy, Front. Bioeng. Biotechnol., 2023, 11: 1217918. 10.3389/fbioe.2023.1217918.
- Weinhandl, J.T., Bennett, H.J., Musculoskeletal model choice influences hip joint load estimations during gait, J. Biomech., 2019, 91: 124–132. 10.1016/j.jbiomech.2019.05.015.
- Montefiori, E., Hayford, C.F., Mazzà, C., Variations of lower-limb joint kinematics associated with the use of different ankle joint models, J. Biomech., 2022, 136: 111072. 10.1016/j.jbiomech.2022.111072.
- Trinler, U., Schwameder, H., Baker, R., Alexander, N., Muscle force estimation in clinical gait analysis using AnyBody and OpenSim, J. Biomech., 2019, 86: 55–63. 10.1016/j.jbiomech.2019.01.045.
- Gautam, K., Hefzy, M.S., Mustapha, A.A., Kyle, B., Comparison of OpenSim and AnyBody Modeling System™ Predictions in Biomechanical Modeling of Upper Extremities, Int. J. Res. Orthop., 2024, 10(4): 717–724. 10.18203/issn.2455-4510.IntJResOrthop20241695.
- Alexander, N., Schwameder, H., Baker, R., Trinler, U., Effect of different walking speeds on joint and muscle force estimation using AnyBody and OpenSim, Gait. Posture., 2021, 90: 197–203. 10.1016/j.gaitpost.2021.08.026.
- Ashtiani, M.B, Akhavanfar, M., Li, L., Kim, S., Nussbaum, M.A., Using musculoskeletal models to estimate the effects of exoskeletons on spine loads during dynamic lifting tasks: differences between OpenSim and the AnyBody modelling system, J. Biomech., 2025, 188: 112780. 10.1016/j.jbiomech.2025.112780.
- Kainz, H., Schwartz, M.H., 2021. The importance of a consistent workflow to estimate muscle-tendon lengths based on joint angles from the conventional gait model, Gait Posture, 2021, 88: 1–9. 10.1016/j.gaitpost.2021.04.039.
- Trinler, U., Hollands, K., Jones, R., Baker, R., A systematic review of approaches to modelling lower limb muscle forces during gait: applicability to clinical gait analyses, Gait Posture, 2018a, 61: 353–361. 10.1016/j.gaitpost.2018.02.005.
- Trinler, U., Leboeuf, F., Hollands, K., Jones, R., Baker, R., Estimation of muscle activation during different walking speeds with two mathematical approaches compared to surface EMG, Gait Posture, 2018b, 64: 266–273. 10.1016/j.gaitpost.2018.06.115.
- Wagner, D.W., Stepanyan, V., Shippen, J.M., Demers, M.S., Gibbons, R.S., Andrews, B.J., et al., Consistency among musculoskeletal models: caveat utilitor, Ann. Biomed. Eng., 2013, 41: 1787–1799. 10.1007/s10439-013-0843-1.
- Andersen, M.S., Introduction to musculoskeletal modelling. In: Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System, Woodhead Publ Ser Biomater, Woodhead Publishing, 2021, pp. 41–80, ISBN 9780128195314.
- Delp, S.L., Anderson, F.C., Arnold, A.S., Loan, P., Habib, A., John, C.T., et al., OpenSim: open-source software to create and analyze dynamic simulations of movement, IEEE Trans. Biomed. Eng., 2007, 54(11): 1940–1950. 10.1109/TBME.2007.901024.
- Koller, W., Baca, A., Kainz, H., Impact of scaling errors of the thigh and shank segments on musculoskeletal simulation results, Gait Posture, 2021, 87: 65–74. 10.1016/j.gaitpost.2021.02.016.
- Wesseling, M., Derikx, L.C., de Groote, F., Bartels, W., Meyer, C., Verdonschot, N., et al., Muscle optimization techniques impact the magnitude of calculated hip joint contact forces, J. Orthop. Res., 2015, 33: 430–438. 10.1002/jor.22769.
- Ismail, K.K., Lewis, C.L., Effect of simulated changes in pelvic tilt on hip joint forces, J. Biomech., 2022, 135:111048. 10.1016/j.jbiomech.2022.111048.
- Klein-Horsman, M.D., Koopman, H.F., van der Helm, F.C., Prosé, L.P., Veeger, H.E., Morphological muscle and joint parameters for musculoskeletal modelling of the lower extremity, Clin. Biomech., 2007, 22: 239–247. 10.1016/j.clinbiomech.2006.10.003.
- Carbone, V., Fluit, R., Pellikaan, P., van der Krogt, M., Janssen, D., Damsgaard, M., et al., TLEM 2.0 – A comprehensive musculoskeletal geometry dataset for subject-specific modeling of lower extremity, J. Biomech., 2015, 48(5): 734–741. 10.1016/j.jbiomech.2014.12.034.
- de Pieri, E., Lund, M.E., Gopalakrishnan, A., Rasmussen, K.P., Lunn, D.E., Ferguson, S.J., Refining muscle geometry and wrapping in the TLEM 2 model for improved hip contact force prediction, PLoS One, 2018, 13: e0204109. 10.1371/journal.pone.0204109.
- Wu, G., Siegler, S., Allard, P., Kirtley, C., Leardini, A., Rosenbaum, D., et al., ISB recommendation on definitions of joint coordinate system of various joints for the reporting of human joint motion—Part I: ankle, hip, and spine, J. Biomech., 2002, 35(4): 543–548. 10.1016/s0021-9290(01)00222-6.
- Prilutsky, B.I., Zatsiorsky, V.M., Optimization-based models of muscle coordination, Exerc. Sport Sci. Rev., 2002, 30(1): 32–38. 10.1097/00003677-200201000-00007.
- Yona, T., Kamel, N., Cohen-Eick, G., Ovadia, I., Fischer, A., One-dimension statistical parametric mapping in lower limb biomechanical analysis: A systematic scoping review, Gait Posture, 2024, 109: 133–146. 10.1016/j.gaitpost.2024.01.018.
- Pataky, T.C., One-dimensional statistical parametric mapping in Python, Comput. Methods Biomech. Biomed. Engin., 2012, 15(3): 295–301. 10.1080/10255842.2010.527837.
- Pataky, T. C., Robinson, M. A., Vanrenterghem, J., Vector field statistical analysis of kinematic and force trajectories, J. Biomech., 2013, 46(14): 2394–2401. 10.1016/j.jbiomech.2013.07.031.
- Aleksandrowicz, K., Kosakowski, W., Michalska, A., Winiarski, S., SPM differences in gait pattern of women after total hip replacement: A longitudinal study, J. Clin. Med., 2025, 14(12): 4316. 10.3390/jcm14124316.
- Park, J., Han, K., Quantifying gait asymmetry in stroke patients: A statistical parametric mapping (SPM) approach, Med. Sci. Monit., 2025, 31: e946754. 10.12659/MSM.946754.
- Harrington, M.S., Di Leo, S.D.F., Hlady, C.A., Burkhart, T.A., Musculoskeletal modeling and movement simulation for structural hip disorder research: A scoping review of methods, validation, and applications, Heliyon, 2024, 10(15): e35007. 10.1016/j.heliyon.2024.e35007.
- Kainz, H., Hoang, H.X., Stockton, C., Boyd, R.N., Lloyd, D.G., Carty, C.P., Accuracy and reliability of marker-based approaches to scale the pelvis, thigh, and shank segments in musculoskeletal models, J. Appl. Biomech., 2017, 33(5): 354–360. 10.1123/jab.2016-0282.
- Modenese, L., Renault, J.B., Automatic generation of personalised skeletal models of the lower limb from three-dimensional bone geometries, J. Biomech., 2021, 116: 110186. 10.1016/j.jbiomech.2020.110186.
- Mestanza Mattos, F.G., Luciano, F., Lencioni, T., Gervasoni, E., Jonsdottir, J., Anastasi, D., et al., Complementary use of statistical parametric mapping and gait profile score to describe walking alterations in multiple sclerosis: a cross-sectional study, Sci. Rep., 2023, 13: 10465. 10.1038/s41598-023-36916-5.
Language: English
Page range: 86 - 98
Submitted on: Dec 5, 2025
Accepted on: Mar 23, 2026
Published on: Oct 15, 2026
Published by: Wroclaw University of Science and Technology
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© 2026 Justyna Skubich, Szczepan Piszczatowski, published by Wroclaw University of Science and Technology
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