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Synchronous Invasive Ductal Carcinoma of Breast and Diffuse Large B-cell Lymphoma: A Case Report Cover

Synchronous Invasive Ductal Carcinoma of Breast and Diffuse Large B-cell Lymphoma: A Case Report

Journal of Cancer and Allied Specialties
Volume 10 (2024): Issue 2 (August 2024)
By: Tahira Yasmeen,  Sobia Umar and  Mariah Mairah Razi  
Open Access
|Aug 2024

Figures & Tables

Figure 1:

(a) Right axillary lymph node trucut biopsy; diffuse large B-cell lymphoma. (b) CD 20: Positive in tumor cells. (c) Ki67; 50% proliferation index in tumor cells. (d) Cytokeratin; negative in tumor cells
(a) Right axillary lymph node trucut biopsy; diffuse large B-cell lymphoma. (b) CD 20: Positive in tumor cells. (c) Ki67; 50% proliferation index in tumor cells. (d) Cytokeratin; negative in tumor cells

Figure 2:

(a) Right breast trucut biopsy: Invasive breast carcinoma, no special type (ductal), grade II. (b) Her 2: Equivocal: Score 2+ (uniform, intense complete membranous staining in: 5–10% cells). (c) Estrogen receptor; positive, strong staining in 95% of tumor cells. (d) progesterone receptor; positive, strong staining in 50% of tumor cells
(a) Right breast trucut biopsy: Invasive breast carcinoma, no special type (ductal), grade II. (b) Her 2: Equivocal: Score 2+ (uniform, intense complete membranous staining in: 5–10% cells). (c) Estrogen receptor; positive, strong staining in 95% of tumor cells. (d) progesterone receptor; positive, strong staining in 50% of tumor cells

Figure 3:

Baseline scan April 2023 (a) axial computed tomography (CT), (b) positron emission tomography only, (c) fused positron emission tomography-CT images through the chest showed fludeoxyglucose (FDG) avid soft tissue mass in the upper outer quadrant of right breast (yellow arrow) has SUV 7.4. FDG avid right axillary lymph nodes (SUV 3.7) are marked with blue arrows, consistent with DLBCL. Small volume mildly avid mediastinal and hilar lymph nodes are likely reactive. (d) Coronal positron emission tomography-only images show hypermetabolic right breast biopsy-proven ductal carcinoma in situ
Baseline scan April 2023 (a) axial computed tomography (CT), (b) positron emission tomography only, (c) fused positron emission tomography-CT images through the chest showed fludeoxyglucose (FDG) avid soft tissue mass in the upper outer quadrant of right breast (yellow arrow) has SUV 7.4. FDG avid right axillary lymph nodes (SUV 3.7) are marked with blue arrows, consistent with DLBCL. Small volume mildly avid mediastinal and hilar lymph nodes are likely reactive. (d) Coronal positron emission tomography-only images show hypermetabolic right breast biopsy-proven ductal carcinoma in situ

Figure 4:

Follow-up scan June 2023 (a) axial computed tomography (CT), (b) positron emission tomography only, (c) fused positron emission tomography-CT images through the chest showed significant interval decrease in size and metabolic activity of right breast mgass (yellow arrows) with faint uptake (SUV 2.6). Right axillary lymphadenopathy has also significantly reduced leaving behind residual non-avid (SUV 1.2) subcentimeter nodes (blue arrows). (d) Coronal positron emission tomography-only images showed a faintly avid residual tumor in the right breast
Follow-up scan June 2023 (a) axial computed tomography (CT), (b) positron emission tomography only, (c) fused positron emission tomography-CT images through the chest showed significant interval decrease in size and metabolic activity of right breast mgass (yellow arrows) with faint uptake (SUV 2.6). Right axillary lymphadenopathy has also significantly reduced leaving behind residual non-avid (SUV 1.2) subcentimeter nodes (blue arrows). (d) Coronal positron emission tomography-only images showed a faintly avid residual tumor in the right breast
DOI: https://doi.org/10.37029/jcas.v10i2.655 | Journal eISSN: 2411-989X
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Language: English
Page range: 1 - 5
Submitted on: Feb 19, 2024
Accepted on: May 3, 2024
Published on: Aug 16, 2024
Published by: Shakuat Khanum Memorial Cancer Hospital and Research Centre
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
Diffuse large B cell lymphoma,
invasive ductal carcinoma of the breast,
multiple primary malignancies,
synchronous
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Internal medicine, other,
Haematology, oncology,
Pediatrics and juvenile medicine,
Paediatric haematology and oncology,
Surgery,
Surgery, other

© 2024 Tahira Yasmeen, Sobia Umar, Mariah Mairah Razi, published by Shakuat Khanum Memorial Cancer Hospital and Research Centre
This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.

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