Distinct Gut Microbiome and Metabolome Profiles Associate with Differential Responses to Immunotherapy in Colorectal Cancer
By: Fang Liang, Jing Li, Yingkun Yue, Jiaxin Pan, Chenyu Liu, Duo Cheng, Nan Zhang, Kunkun Li, Feifei Chu and Huili Wu
Authors
Fang Liang
Department of Oncology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Jing Li
Department of Oncology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Medical Key Laboratory for Diagnosis and Treatment of Colorectal Cancer in Henan Province, Zhengzhou, China
Zhengzhou Key Laboratory for Diagnosis, Treatment and Research of Colorectal Cancer, Zhengzhou, China
Yingkun Yue
Department of Oncology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Jiaxin Pan
Department of Hepatobiliary and Pancreatic Surgery, People’s Hospital of Henan University, Zhengzhou, China
Chenyu Liu
Department of Oncology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Duo Cheng
Department of Oncology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Nan Zhang
Department of Oncology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Kunkun Li
Department of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Feifei Chu
Medical Key Laboratory for Diagnosis and Treatment of Colorectal Cancer in Henan Province, Zhengzhou, China
Zhengzhou Key Laboratory for Diagnosis, Treatment and Research of Colorectal Cancer, Zhengzhou, China
Department of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Huili Wu
Medical Key Laboratory for Diagnosis and Treatment of Colorectal Cancer in Henan Province, Zhengzhou, China
Zhengzhou Key Laboratory for Diagnosis, Treatment and Research of Colorectal Cancer, Zhengzhou, China
Department of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
Language: English
Page range: 168 - 194
Submitted on: Dec 25, 2025
Accepted on: Apr 22, 2026
Published on: Jun 30, 2026
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
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© 2026 Fang Liang, Jing Li, Yingkun Yue, Jiaxin Pan, Chenyu Liu, Duo Cheng, Nan Zhang, Kunkun Li, Feifei Chu, Huili Wu, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.