Pheno- and Genotypic Epidemiological Characterization of Vancomycin-Resistant Enterococcus faecium Isolates from Intensive Care Unit Patients in Central Türkiye

Akineden, Altan; ÇiÇek, Cemal; TÜrkel, SelÇuk; Khan, Izhar U.H.; Abdulmawjood, Amir

Pheno- and Genotypic Epidemiological Characterization of Vancomycin-Resistant Enterococcus faecium Isolates from Intensive Care Unit Patients in Central Türkiye

Polish Journal of Microbiology

Volume 73 (2024): Issue 3 (September 2024)

By:

Altan Akineden, Cemal ÇiÇek, SelÇuk TÜrkel, Izhar U.H. Khan and Amir Abdulmawjood

Open Access

|Sep 2024

Figures & Tables

Dendrogram showing the MRFP patterns of 22 vancomycin-resistant Enterococcus faecium isolates, denoted MRFP types P1 to P9, obtained from 22 patients digested with the SmaI restriction enzyme. The dendrogram was constructed with the BioNumerics v6.6 (Applied Maths, Belgium) program, with the Dice coefficient setting tolerance and optimization at 1.0% and 2.0% with 95% similarity cut-off value. Hospital ward: ICU – intensive care unit, IICU – internal medicine intensive care unit, NU – neurointensive care unit.

Relationship between MRFP types and antimicrobial susceptibility profiles of vancomycin-resistant Enterococcus faecium isolates (n = 22)_

MRFP pattern	Number of isolates/patients^a	Isolate code	Hospital ward^b	Gender	Age	Date of admission	Diagnostics	Short-term outcome	Susceptibility profile^c							Resistance pattern
MRFP pattern	Number of isolates/patients^a	Isolate code	Hospital ward^b	Gender	Age	Date of admission	Diagnostics	Short-term outcome	AMP	CIP	GN	TEC	VA	LNZ	TGC	Resistance pattern
Pl	2	EN2	ICU	female	79	25.08.2021	pneumonia, cerebral infarction	died	R	R	S	R	R	S	S	I
Pl	2	EN5	IICU	male	57	06.10.2021	pneumonia, chronic obstructive pulmonary disease	died	R	R	R	R	R	S	S	II
P2	7	EN1	ICU	female	40	20.08.2021	pneumonia septicemia, encephalopathy	died	R	R	S	R	R	S	S	I
		EN4	ICU	female	82	22.10.2021	pneumonia, cerebrovascular disease, heart failure	recovered	R	R	R	R	R	S	S	II
		EN9	ICU	female	63	11.11.2021	cerebrovascular disease, coronary artery disease	died	R	R	R	R	R	S	S	II
		EN10	ICU	male	70	16.02.2022	pneumonia chronic obstructive pulmonary disease, heart failure	died	R	R	R	R	R	S	S	II
		EN14	ICU	male	29	26.03.2022	pneumonia, epilepsy	recovered	R	R	R	R	R	S	S	II
		EN15	NU	male	71	03.04.2022	pneumonia, cerebrovascular disease, acute renal failure	died	R	R	S	R	R	S	S	I
		EN20	ICU	female	52	26.06.2022	pneumonia, septicemia, urinary tract infection	died	R	R	R	R	R	S	S	II
P3	2	EN21	ICU	male	71	16.09.2021	acute renal failure, hypertension	died	R	R	R	R	R	S	S	II
P3	2	EN22	ICU	male	68	22.09.2021	pneumonia, atherosclerotic heart disease	died	R	R	R	R	R	S	S	II
P4	1	EN3	IICU	female	77	22.10.2021	pneumonia, cerebrovascular disease	died	R	R	R	R	R	S	S	II
P4a	1	EN6	ICU	female	87	27.11.2021	pneumonia, abdominal pain	recovered	R	R	R	R	R	S	S	II
P5	1	EN7	IICU	female	84	20.09.2021	chronic kidney failure, liver cancer	recovered	R	R	R	R	R	S	S	II
P6	1	EN16	ICU	male	79	11.06.2022	chronic obstructive pulmonary disease, heart failure	died	R	R	R	R	R	S	S	II
P6a	1	EN8	IICU	female	62	15.08.2021	diabetes mellitus, urinary tract infection	recovered	R	R	R	R	R	S	S	II
P7	2	ENI 8	IICU	male	62	24.02.2022	syncope, cerebrovascular disease	recovered	R	R	R	R	R	S	S	II
P7	2	EN19	IICU	male	64	29.02.2022	syncope, diabetes mellitus, hypertension	recovered	R	R	R	R	R	S	S	II
P8	2	EN11	ICU	male	64	11.02.2022	pneumonia, cerebrovascular disease, heart failure	died	R	R	R	R	R	S	S	II
P8	2	EN12	ICU	male	93	23.02.2022	pneumonia, chronic obstructive pulmonary disease	died	R	R	S	R	R	S	S	I
P8a	1	EN13	ICU	female	77	10.01.2022	pneumonia, cerebrovascular disease	died	R	R	R	R	R	S	S	II
P9	1	EN17	ICU	male	74	20.06.2022	liver failure, chronic obstructive pulmonary disease	died	R	R	R	R	R	S	S	II

DOI: https://doi.org/10.33073/pjm-2024-030 | Journal eISSN: 2544-4646 | Journal ISSN: 1733-1331

Journal RSS Feed

Language: English

Page range: 403 - 410

Submitted on: Apr 12, 2024

Accepted on: Jun 27, 2024

Published on: Sep 13, 2024

Published by: Polish Society of Microbiologists

In partnership with: Paradigm Publishing Services

Publication frequency: 4 times per year

Keywords:

antimicrobial resistance,

vancomycin resistance,

A gene,

B gene

Related subjects:

Life sciences,

Microbiology and virology

© 2024 Altan Akineden, Cemal ÇiÇek, SelÇuk TÜrkel, Izhar U.H. Khan, Amir Abdulmawjood, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Previous article Volume 73 (2024): Issue 3 (September 2024)Next article

Pheno- and Genotypic Epidemiological Characterization of Vancomycin-Resistant Enterococcus faecium Isolates from Intensive Care Unit Patients in Central Türkiye

Figures & Tables

Fig. 1.

Relationship between MRFP types and antimicrobial susceptibility profiles of vancomycin-resistant Enterococcus faecium isolates (n = 22)_

Paradigm

My account