Have a personal or library account? Click to login
Analysis of the Class 1 Integrons, Carbapenemase Genes and Biofilm Formation Genes Occurrence in Acinetobacter baumannii Clinical Isolates Cover

Analysis of the Class 1 Integrons, Carbapenemase Genes and Biofilm Formation Genes Occurrence in Acinetobacter baumannii Clinical Isolates

By: Yu Xiu,  Yueru Dai,  Shasha Yin and  Quhao Wei  
Open Access
|May 2024

References

  1. Aliramezani A, Douraghi M, Hajihasani A, Mohammadzadeh M, Rahbar M. Clonal relatedness and biofilm formation of OXA-23--producing carbapenem resistant Acinetobacter baumannii isolates from hospital environment. Microb Pathog. 2016 Oct;99:204–208. https://doi.org/10.1016/j.micpath.2016.08.034
  2. Azizi O, Shahcheraghi F, Salimizand H, Modarresi F, Shakibaie MR, Mansouri Sh, Ramazanzadeh R, Badmasti F, Nikbin V. Molecular analysis and expression of bap gene in biofilm-forming multi-drug-resistant Acinetobacter baumannii. Rep Biochem Mol Biol. 2016 Oct; 5(1):62–72.
  3. Barraud O, Ploy MC. Diversity of class 1 integron gene cassette rearrangements selected under antibiotic pressure. J Bacteriol. 2015 Jul;197(13):2171–2178. https://doi.org/10.1128/JB.02455-14
  4. Cai X, Hu Z, Li J, Li Y, Tian B. [Clinical isolates of Acinetobacter baumannii from bloodstream infections: PFGE characterization and virulence-associated factors] (in Chinese). Chin J Lab Med. 2017 Mar;40(3):201–205.
  5. Chukamnerd A, Singkhamanan K, Chongsuvivatwong V, Palittapongarnpim P, Doi Y, Pomwised R, Sakunrang C, Jeenkeawpiam K, Yingkajorn M, Chusri S, et al. Whole-genome analysis of carbapenem-resistant Acinetobacter baumannii from clinical isolates in Southern Thailand. Comput Struct Biotechnol J. 2022 Jan;20:545–558. https://doi.org/10.1016/j.csbj.2021.12.038
  6. CLSI. Performance standards for antimicrobial susceptibility testing. 31st ed. CLSI supplement M100. Wayne (USA): Clinical and Laboratory Standards Institute; 2021.
  7. Couvé-Deacon E, Jové T, Afouda P, Barraud O, Tilloy V, Scaon E, Hervé B, Burucoa C, Kempf M, Marcos JY, et al. Class 1 integrons in Acinetobacter baumannii: A weak expression of gene cassettes to counterbalance the lack of LexA-driven integrase repression. Int J Antimicrob Agents. 2019 Apr;53(4):491–499. https://doi.org/10.1016/j.ijantimicag.2018.11.012
  8. Dolma KG, Khati R, Paul AK, Rahmatullah M, de Lourdes Pereira M, Wilairatana P, Khandelwal B, Gupta C, Gautam D, et al. Virulence characteristics and emerging therapies for biofilm-forming Acinetobacter baumannii: A review. Biology. 2022 Sep; 11(9):1343. https://doi.org/10.3390/biology11091343
  9. El-Ageery SM, Al-Hazmi SS. Microbiological and molecular detection of VIM-1 metallo beta lactamase-producing Acinetobacter baumannii. Eur Rev Med Pharmacol Sci. 2014;18(7):965–970.
  10. Gillings MR. Integrons: Past, present, and future. Microbiol Mol Biol Rev. 2014 Jun;78(2):257–277. https://doi.org/10.1128/MMBR.00056-13
  11. Greene C, Vadlamudi G, Newton D, Foxman B, Xi C. The influence of biofilm formation and multidrug resistance on environmental survival of clinical and environmental isolates of Acinetobacter baumannii. Am J Infect Control. 2016 May;44(5):e65–e71. https://doi.org/10.1016/j.ajic.2015.12.012
  12. Harding CM, Hennon SW, Feldman MF. Uncovering the mechanisms of Acinetobacter baumannii virulence. Nat Rev Microbiol. 2018 Feb;16(2):91–102. https://doi.org/10.1038/nrmicro.2017.148
  13. Huang Y, Zhou Q, Wang W, Huang Q, Liao J, Li J, Long L, Ju T, Zhang Q, Wang H, et al. Acinetobacter baumannii ventilator-associated pneumonia: Clinical efficacy of combined antimicrobial therapy and in vitro drug sensitivity test results. Front Pharmacol. 2019 Feb; 10:92. https://doi.org/10.3389/fphar.2019.00092
  14. Ibrahim ME. Prevalence of Acinetobacter baumannii in Saudi Arabia: Risk factors, antimicrobial resistance patterns and mechanisms of carbapenem resistance. Ann Clin Microbiol Antimicrob. 2019 Jan; 18(1):1. http://doi.org/10.1186/s12941-018-0301-x
  15. Ibrahim S, Al-Saryi N, Al-Kadmy IMS, Aziz SN. Multidrug-resistant Acinetobacter baumannii as an emerging concern in hospitals. Mol Biol Rep. 2021 Oct;48(10):6987–6998. https://doi.org/10.1007/s11033-021-06690-6
  16. Jia H, Sun Q, Ruan Z, Xie X. Characterization of a small plasmid carrying the carbapenem resistance gene blaOXA-72 from community-acquired Acinetobacter baumannii sequence type 880 in China. Infect Drug Resist. 2019 Jun;12:1545–1553. https://doi.org/10.2147/IDR.S202803
  17. Khorsi K, Messai Y, Hamidi M, Ammari H, Bakour R. High prevalence of multidrug-resistance in Acinetobacter baumannii and dissemination of carbapenemase-encoding genes blaOXA-23-like, blaOXA-24-like and blaNDM-1 in Algiers hospitals. Asian Pac J Trop Med. 2015 Jun;8(6):438–446. https://doi.org/10.1016/j.apjtm.2015.05.011
  18. Khoshnood S, Sadeghifard N, Mahdian N, Heidary M, Mahdian S, Mohammadi M, Maleki A, Haddadi MH. Antimicrobial resistance and biofilm formation capacity among Acinetobacter baumannii strains isolated from patients with burns and ventilator-associated pneumonia. J Clin Lab Anal. 2023 Jan;37(1):e24814. https://doi.org/10.1002/jcla.24814
  19. Kim SY, Kim MH, Kim SI, Son JH, Kim S, Lee YC, Shin M, Oh MH, Lee JC. The sensor kinase BfmS controls production of outer membrane vesicles in Acinetobacter baumannii. BMC Microbiol. 2019 Dec;19(1):301. https://doi.org/10.1186/s12866-019-1679-0
  20. Lacotte Y, Ploy MC, Raherison S. Class 1 integrons are low-cost structures in Escherichia coli. ISME J. 2017 Jul;11(7):1535–1544. https://doi.org/10.1038/ismej.2017.38
  21. Larsen MV, Cosentino S, Lukjancenko O, Saputra D, Rasmussen S, Hasman H, Sicheritz-Pontén T, Aarestrup FM, Ussery DW, Lund O. Benchmarking of methods for genomic taxonomy. J Clin Microbiol. 2014 May;52(5):1529–1539. https://doi.org/10.1128/JCM.02981-13
  22. Lasarte-Monterrubio C, Guijarro-Sánchez P, Bellés A, Vázquez-Ucha JC, Arca-Suárez J, Fernández-Lozano C, Bou G, Beceiro A; Spanish National Study Acinetobacter spp. 2020 Group. Carbapenem resistance in Acinetobacter nosocomialis and Acinetobacter junii conferred by acquisition of blaOXA-24/40 and genetic characterization of the transmission mechanism between Acinetobacter genomic species. Microbiol Spectr. 2022 Feb;10(1):e0273421. https://doi.org/10.1128/spectrum.02734-21
  23. Lee CR, Lee JH, Park M, Park KS, Bae IK, Kim YB, Cha CJ, Jeong BC, Lee SH. Biology of Acinetobacter baumannii: Pathogenesis, antibiotic resistance mechanisms, and prospective treatment options. Front Cell Infect Microbiol. 2017 Mar;7:55. https://doi.org/10.3389/fcimb.2017.00055
  24. Migliaccio A, Bray J, Intoccia M, Stabile M, Scala G, Jolley KA, Brisse S, Zarrilli R. Phylogenomics of Acinetobacter species and analysis of antimicrobial resistance genes. Front Microbiol. 2023 Oct;14:1264030. https://doi.org/10.3389/fmicb.2023.1264030
  25. Nikibakhsh M, Firoozeh F, Badmasti F, Kabir K, Zibaei M. Molecular study of metallo-β-lactamases and integrons in Acinetobacter baumannii isolates from burn patients. BMC Infect Dis. 2021 Aug;21(1):782. https://doi.org/10.1186/s12879-021-06513-w
  26. Pakharukova N, Tuittila M, Paavilainen S, Malmi H, Parilova O, Teneberg S, Knight SD, Zavialov AV. Structural basis for Acinetobacter baumannii biofilm formation. Proc Natl Acad Sci USA. 2018 May;115(21):5558–5563. https://doi.org/10.1073/pnas.1800961115
  27. Rodríguez-Baño J, Martí S, Soto S, Fernández-Cuenca F, Cisneros JM, Pachón J, Pascual A, Martínez-Martínez L, McQueary C, Actis LA, et al; Spanish Group for the Study of Nosocomial Infections (GEIH). Biofilm formation in Acinetobacter baumannii: Associated features and clinical implications. Clin Microbiol Infect. 2008 Mar;14(3):276–278. https://doi.org/10.1111/j.1469-0691.2007.01916.x
  28. Rodríguez-Martínez JM, Poirel L, Nordmann P. Genetic and functional variability of AmpC-type β-lactamases from Acinetobacter baumannii. Antimicrob Agents Chemother. 2010 Nov;54(11): 930–4933. https://doi.org/10.1128/AAC.00427-10
  29. Roy S, Chowdhury G, Mukhopadhyay AK, Dutta S, Basu S. Convergence of biofilm formation and antibiotic resistance in Acinetobacter baumannii infection. Front Med. 2022 Mar;9:793615. https://doi.org/10.3389/fmed.2022.793615
  30. Sun X, Ni Z, Tang J, Ding Y, Wang X, Li F. The abaI/abaR quorum sensing system effects on pathogenicity in Acinetobacter baumannii. Front Microbiol. 2021 Jul;12:679241. https://doi.org/10.3389/fmicb.2021.679241
  31. Villegas MV, Kattan JN, Correa A, Lolans K, Guzman AM, Woodford N, Livermore D, Quinn JP. Dissemination of Acinetobacter baumannii clones with OXA-23 carbapenemase in Colombian hospitals. Antimicrob Agents Chemother. 2007 Jun;51(6):2001–2004. https://doi.org/10.1128/AAC.00226-07
  32. Wang T, Zhu Y, Zhu W, Cao M, Wei Q. Molecular characterization of class 1 integrons in carbapenem-resistant Enterobacterales isolates. Microb Pathog. 2023 Apr;177:106051. https://doi.org/10.1016/j.micpath.2023.106051
  33. Wang X, Ye Y. [The correlation analysis of the resistance and virulence genes of penicillium carbon alkene resistant Acinetobacter baumannii] (in Chinese). Chin J Antibio. 2021 Dec;46(7):699–705.
  34. Wei Q, Hu Q, Li S, Lu H, Chen G, Shen B, Zhang P, Zhou Y. A novel functional class 2 integron in clinical Proteus mirabilis isolates. J Antimicrob Chemother. 2014 Apr;69(4):973–976. https://doi.org/10.1093/jac/dkt456
  35. Wei Q, Jiang X, Li M, Chen X, Li G, Li R, Lu Y. Transcription of integron-harboured gene cassette impacts integration efficiency in class 1 integron. Mol Microbiol. 2011 Jun;80(5):1326–1336. https://doi.org/10.1111/j.1365-2958.2011.07648.x
  36. Wei Q, Jiang X, Li M, Li G, Hu Q, Lu H, Chen G, Zhou Y, Lu Y. Diversity of gene cassette promoter variants of class 1 integrons in uropathogenic Escherichia coli. Curr Microbiol. 2013 Nov;67(5): 543–549. https://doi.org/10.1007/s00284-013-0399-1
  37. Wick RR, Judd LM, Gorrie CL, Holt KE. Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads. PLoS Comput Biol. 2017 Jun;13(6):e1005595. https://doi.org/10.1371/journal.pcbi.1005595
  38. Xiao C, Cao M, Zhang L, Kong N, Wang X, Xiao L, Wei Q. [Distribution of integrons and antimicrobial resistance in carbapenem-resistant Acinetobacter baumannii clinical strains] (in Chinese). Chin J Microbiol Immunol. 2019 Apr;39(4):277–282.
  39. Zhang Q, Cheng X, Shen J. [Detection of carbapenemases and integrons in carbapenem-resistant Acinetobacter baumannii] (in Chinese). Chin J Antibiot. 2015 May;40(5):377–381.
DOI: https://doi.org/10.33073/pjm-2024-017 | Journal eISSN: 2544-4646 | Journal ISSN: 1733-1331
Language: English
Page range: 189 - 197
Submitted on: Dec 9, 2023
|
Accepted on: Mar 28, 2024
|
Published on: May 29, 2024
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Yu Xiu, Yueru Dai, Shasha Yin, Quhao Wei, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.