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Synthesis, anticancer and cytostatic activity of some 6H-indolo[2,3-b]quinoxalines Cover

Synthesis, anticancer and cytostatic activity of some 6H-indolo[2,3-b]quinoxalines

Open Access
|Nov 2009

References

  1. D. J. Brown (Ed.), Quinoxalines, Wiley, New York 2004.10.1002/0471533408
  2. G. W. H. Cheeseman and R. F. Cookson (Eds.), Condensed Pyrazines, Wiley, New York 1979.
  3. A. Carta, P. Corona and M. Loriga, Quinoxaline 1,4-dioxide: A versatile scaffold end-owed with manifold activities, Curr. Med. Chem. 12 (2005) 2259-2272; DOI: 10.2174/0929867054864831.10.2174/092986705486483116178784
  4. J. Harrmenberg, B. Wahren, J. Bergman, S. Akerfeldt and L. Lundbland, Antiherpes virus activity and mechanism of action of indolo[2,3-b]-quinoxaline and analogs, Antimicrob. Agents Chemother. 32 (1988) 1720-1724.10.1128/AAC.32.11.17201759572855298
  5. J. O. E. Bergman and S. G. Aakerfeldt, Indoloquinoxalines with Substitutients in 6-Position Containing Cyclic Groups, Eur. Pat. 0, 231, 159, 18 Sep 1987; ref. Chem. Abstr. 108 (1988) 6048s.
  6. N. Patel, J. Bergman and A. Graslund, Interaction of the deoxy-oligonucleotide duplex d(CGCGATCGCG)2 and anti-hepres virus active indolo[2,3-b]-quinoxaline derivatives, Nucleos. Nucleot. Nucl. 10 (1991) 699-700; DOI: 10.1080/07328319108046576.10.1080/07328319108046576
  7. B. Zarranz, A. Jaso, I. Aldana, A. Monge, S. Maurel, E. Deharo, V. Jullian and M. Sauvain, Synthesis and antimalarial activity of new 3-arylquinoxaline-2-carbonitrile derivatives, Arzneim. Forsch. 55 (2005) 754-761.
  8. G. Moarbess, C. Deleuze-Masquefa, V. Bonnard, S. Gayraud-Paniagua, J. Vidal, F. Bressolle, F. Pinguet and B. Pierre-Antoine, In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives, Bioorg. Med. Chem. 16 (2008) 6601-6610; DOI:10.1016/j.bmc.2008.05.022.10.1016/j.bmc.2008.05.02218513976
  9. K. Toshima, T. Ozawa, T. Kimura and S. Matsumura, The significant effect of the carbohydrate structures on the DNA photocleavage of the quinoxaline-carbohydrate hybrids, Bioorg. Med. Chem. Lett. 14 (2004) 2777-2779; DOI: 10.1016/j.bmcl.2004.03.065.10.1016/j.bmcl.2004.03.06515125931
  10. G. A. Carter, T. Clark, C. S. James and R. S. T. Loeffler, Fungicidal activities of substituted quinoxalines, Pestic. Sci. 14 (1983) 135-144; DOI: 10.1002/ps.2780140207.10.1002/ps.2780140207
  11. P. Sanna, A. Carta, M. Loriga, S. Zanetti and L. Sechi, Preparation and biological evaluation of 6/7-trifluoromethyl(nitro)-, 6,7-difluoro-3-alkyl (aryl)-substituted-quinoxalin-2-ones, Farmaco 54 (1999) 169-177; DOI: 10.1016/S0014-827X (99)00011-7.
  12. J. P. Dirlam, J. E. Presslitz and B. J. Williams, Synthesis and antibacterial activity of some 3(alkylthio) methyl]quinoxaline-1-oxide derivatives, J. Med. Chem. 26 (1983) 1122-1126; DOI: 10.1021/jm00362a007.10.1021/jm00362a0076876079
  13. C. S. Marvel and G. S. Hiers, Isatin, in Organic Syntheses Collection (Ed. A. H. Blatt), 2nd ed., Vol 1, Wiley, New York 1941, pp. 327-330.
  14. J. Azizian, F. B. Shaidaei and H. Kefayati, A facile one-pot method for the preparation of N-alkyl isatins under microwave irradiation, Synth. Commun. 33 (2003) 789-793; DOI: 10.1081/SCC-120016324.10.1081/SCC-120016324
  15. A. Monks, D. Scudiero, P. Skehen, R. Shoemaker, K. Paull, D. Vistica, C. Hose, J. Langley, P. Cronise and A. Vaigro-Wolff, Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines, J. Natl. Cancer Inst. 83 (1991) 757-766; DOI: 10.1093/jnci/83.11.757.10.1093/jnci/83.11.7572041050
  16. P. G. Baraldi, M. Del Carmen Nunez, M. A. Tabrizi, E. De Clercq, J. Balzarini, J. Bermejo, F. Este'vez and R. Romagnoli, Design, synthesis and biological evaluation of hybrid molecules containing α-methylene-γ-butyrolactones and polypyrrole minor groove binders, J. Med. Chem. 47 (2004) 2877-2886; DOI: 10.1021/jm031104y.10.1021/jm031104y15139766
DOI: https://doi.org/10.2478/v10007-009-0040-9 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 431 - 440
Published on: Nov 16, 2009
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2009 Subhas Karki, Rahul Hazare, Sujeet Kumar, Vivek Bhadauria, Jan Balzarini, Erik De Clercq, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 59 (2009): Issue 4 (December 2009)