From Clinical Question to Defensible Inference: A Decision Framework for Integrated Gut Microbiome–Metabolome Studies
Authors
Monica Manciulea Profir
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Department of Medical Oncology, SANADOR Oncology Hospital, Bucharest, Romania
Ruxandra F. Ionescu
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Department of Cardiology I, “Dr. Carol Davila” Central Military Emergency Hospital, Bucharest, Romania
Oana A. Popescu Roşu
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Outpatient Oncology Department, Institute of Phono-Audiology and Functional Otorhinolaryngology Surgery “Prof. Dr. D. Hociotă”, Bucharest, Romania
Alin Constantin Stancu
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Ioana Cucu
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Sanda Maria Cretoiu
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Luciana Alexandra Pavelescu
Department of Morphological Sciences, Cell and Molecular Biology and Histology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
DOI: https://doi.org/10.2478/rjim-2026-0022 | Journal eISSN: 2501-062X (formerly 1220-4749) | Journal ISSN: 1220-4749
Language: English, Romanian
Submitted on: Jul 30, 2026
Published on: Oct 22, 2026
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Keywords:
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© 2026 Monica Manciulea Profir, Ruxandra F. Ionescu, Oana A. Popescu Roşu, Alin Constantin Stancu, Ioana Cucu, Sanda Maria Cretoiu, Luciana Alexandra Pavelescu, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.