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Mortality predictors in patients with ST-segment elevation myocardial infarction presenting no-reflow phenomenon after primary PCI: experience of a tertiary center Cover

Mortality predictors in patients with ST-segment elevation myocardial infarction presenting no-reflow phenomenon after primary PCI: experience of a tertiary center

Open Access
|Aug 2025

Abstract

The mortality rate in subjects with ST-segment elevation acute myocardial infarction (STEMI) is increased because of short- and long-term complications.

Purpose

Our study aims to reveal the death risk and in-hospital mortality predictors in STEMI patients who develop no-reflow phenomenon after primary percutaneous coronary intervention (PCI).

Material and method

Between 01.01.2016–31.03.2018, we performed a prospective study including 656 patients with STEMI. We included only patients who underwent myocardial revascularization through the primary PCI method and developed no-reflow phenomenon.

Results

Our study included 96 patients with STEMI and no-reflow phenomenon after PCI, of whom 14 died. Mortality rate was significantly higher in subjects with anterior STEMI compared with inferior STEMI (42.9% vs. 14.3%). The mortality registered after PCI was significantly higher in the coronary no-reflow phenomenon group compared with the myocardial no-reflow group (p = 0.039). Post-PCI mortality was significantly higher in patients with complications than in those without complications (33.33% vs. 1.75%, p <0.001).

Conclusions

The coronary no-reflow phenomenon has the highest risk of mortality, accounting for more than half of the myocardial infarction cases compared with the myocardial no-reflow phenomenon. Most of the deaths were reported in subjects with STEMI and the no-reflow phenomenon, who developed cardiovascular complications.

DOI: https://doi.org/10.2478/rjim-2025-0016 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749
Language: English
Submitted on: May 19, 2025
Published on: Aug 28, 2025
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Larisa Renata Pantea-Roșan, Ovidiu Țica, Otilia Anca Țica, Mircea Ioachim Popescu, Iulia Bogdan, Alexandra Buzle, Mădălina Ioana Moisi, Vlad Alin Pantea, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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