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Endoscopic Ultrasound-guided Tissue Acquisition of Pancreatic Malignancy: A Retrospective Study at a Tertiary Center Cover

Endoscopic Ultrasound-guided Tissue Acquisition of Pancreatic Malignancy: A Retrospective Study at a Tertiary Center

Romanian Journal of Internal Medicine
Volume 63 (2025): Issue 2 (June 2025)
By: Alexandru Constantinescu,  Christopher Pavel,  Oana-Mihaela Plotogea,  Octavian Andronic,  Andreea Pușcașu,  Florentina Gherghiceanu,  Mădălina Cristina Stan-Ilie and  Vasile Șandru  
Open Access
|Apr 2025

References

  1. TONINI V., ZANNI M. Pancreatic cancer in 2021: What you need to know to win. World J Gastroenterol. 2021; 27(35):5851–5889.
    Search in Google ScholarBack to article
  2. DEPREZ P. H. Future Directions in EUS-guided Tissue Acquisition. Gastrointest Endosc Clin N Am. 2013;24(1):143–149.
    Search in Google ScholarBack to article
  3. KANDEL P., WALLACE, M. B. Advanced EUS Guided Tissue Acquisition Methods for Pancreatic Cancer. Cancers. 2018;10(2):54.
    Search in Google ScholarBack to article
  4. KOVACEVIC B., VILMANN P. EUS tissue acquisition: From A to B. Endosc Ultrasound. 2020;9(4):225.
    Search in Google ScholarBack to article
  5. BARTH, A.B., HUSAIN S.Z. Anatomy, Histology, Embryology and Developmental Anomalies of the Pancreas. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease. 2015:923.
    Search in Google ScholarBack to article
  6. AIER I., SEMWAL R., SHARMA A., VARADWAJ P. K. A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer. Cancer Epidemiol. 2019;58:104–110.
    Search in Google ScholarBack to article
  7. DIMAGNO E., REGAN P., WILSON D., BUXTON J., HATTERY R., SUAREZ J., et al. Ultrasonic endoscope. Lancet. 1980;315(8169):629–63.
    Search in Google ScholarBack to article
  8. VILMANN P., JACOBSEN G. K., HENRIKSEN F. W., HANCKE S. Endoscopic ultrasonography with guided fine needle aspiration biopsy in pancreatic disease. Gastrointest Endosc. 1992;38(2):172–173.
    Search in Google ScholarBack to article
  9. HAWES R.H. The Evolution of EUS - Past, Present and Future. Gastrointest Endosc. 2012;54(Supplement1):806–807.
    Search in Google ScholarBack to article
  10. DAHIYA D. S., CHANDAN S., ALI H., PINNAM B. S. M., GANGWANI M. K., AL BUNNI H. A., et al. Role of therapeutic endoscopic Ultrasound in management of pancreatic cancer: An endoscopic oncologist perspective. Cancers. 2023;15(12):3235.
    Search in Google ScholarBack to article
  11. KURAOKA N., HASHIMOTO S., MATSUI S., TERAI S. Effectiveness of EUS-Guided Fine-Needle Biopsy versus EUS-Guided Fine-Needle Aspiration: A Retrospective Analysis. Diagnostics. 2021;11(6):965.
    Search in Google ScholarBack to article
  12. OH H., KANG H., LEE J. Y., CHOI G. J., CHOI J. S. Diagnostic accuracy of 22/25-gauge core needle in endoscopic ultrasound-guided sampling: systematic review and meta-analysis. Korean J Intern Med. 2016;31(6):1073–1083.
    Search in Google ScholarBack to article
  13. BANG J., HAWES R., VARADARAJULU S. A meta-analysis comparing ProCore and standard fine-needle aspiration needles for endoscopic ultrasound-guided tissue acquisition. Endoscopy. 2015;48(04):339–349.
    Search in Google ScholarBack to article
  14. CHENG B., ZHANG Y., CHEN Q., SUN B., DENG Z., SHAN H., et al. Analysis of fine-needle biopsy vs fine-needle aspiration in diagnosis of pancreatic and abdominal masses: A prospective, multicenter, randomized controlled trial. Clin Gastroenterol Hepatol. 2018;16(8):1314–1321.
    Search in Google ScholarBack to article
  15. CONTI C. B., CEREATTI F., GRASSIA R. Endoscopic ultrasound-guided sampling of solid pancreatic masses: the fine needle aspiration or fine needle biopsy dilemma. Is the best needle yet to come?. World J Gastrointest Endosc. 2019;11(8):454–471.
    Search in Google ScholarBack to article
  16. SBEIT W., KHOURY T. Endoscopic ultrasound fine needle biopsy was not more cost-effective than fine-needle aspiration with rapid on-site evaluation in gastrointestinal lesions diagnosis. Diagn Cytopathol. 2021;49(8):944–947.
    Search in Google ScholarBack to article
  17. DE MOURA D. T. H., MCCARTY T. R., JIRAPINYO P., RIBEIRO I. B., FARIAS G. F. A., RYOU M., et al. Endoscopic Ultrasound Fine-Needle Aspiration versus Fine-Needle Biopsy for Lymph Node Diagnosis: A Large Multicenter Comparative Analysis. Clin Endosc. 2019;53(5):600–610.
    Search in Google ScholarBack to article
  18. WANG J., WU X., YIN P., GUO Q., HOU W., LI Y., et al. Comparing endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) versus fine needle biopsy (FNB) in the diagnosis of solid lesions: study protocol for a randomized controlled trial. Trials. 2016;17(1):198.
    Search in Google ScholarBack to article
  19. LIU K., XIAO A. H., SCHENCK R., BALBALE S., FRENCH D. D., AADAM A. A., et al. Endoscopic Ultrasound (Eus) Guided Fine-Needle Biopsy (Fnb) Is Cost-Effective And Time Saving Over Fine-Needle Aspiration (Fna) For Tissue Acquisition Of Pancreas And Intra-Abdominal Mass Lesions. Gastrointest Endosc. 2020;91(6):AB319.
    Search in Google ScholarBack to article
  20. AADAM A., WANI S., AMICK A., SHAH J., BHAT Y., HAMERSKI C., et al. A randomized controlled cross-over trial and cost analysis comparing endoscopic ultrasound fine needle aspiration and fine needle biopsy. Endosc Int Open. 2015;4(05):E497–E505.
    Search in Google ScholarBack to article
  21. SCHMIDT R. L., WITT B. L., MATYNIA A. P., BARRAZA G., LAYFIELD L. J., ADLER D. G. Rapid On-Site Evaluation Increases Endoscopic Ultrasound-Guided Fine-Needle Aspiration Adequacy for Pancreatic Lesions. Dig Dis Sci. 2012;58(3):872–882.
    Search in Google ScholarBack to article
  22. IWASHITA T., YASUDA I., MUKAI T., DOI S., NAKASHIMA M., UEMURA S., et al. Macroscopic on-site quality evaluation of biopsy specimens to improve the diagnostic accuracy during EUS-guided FNA using a 19-gauge needle for solid lesions: a single-center prospective pilot study (MOSE study). Gastrointest Endosc. 2014;81(1):177–185.
    Search in Google ScholarBack to article
  23. KI E. L., LEMAISTRE A., FUMEX F., GINCUL R., LEFORT C., LEPILLIEZ V., et al. Macroscopic onsite evaluation using endoscopic ultrasound fine needle biopsy as an alternative to rapid onsite evaluation. Endosc Int Open. 2019;07(02):E189–E194.
    Search in Google ScholarBack to article
  24. MANGIAVILLANO B., FRAZZONI L., TOGLIANI T., FABBRI C., TARANTINO I., DE LUCA L., et al. Macroscopic on-site evaluation (MOSE) of specimens from solid lesions acquired during EUS-FNB: multicenter study and comparison between needle gauges. Endosc Int Open. 2021;09(06):E901–E906.
    Search in Google ScholarBack to article
  25. TORPHY R. J., FUJIWARA Y., SCHULICK R. D. Pancreatic cancer treatment: better, but a long way to go. Surg Today. 2020;50(10):1117–1125.
    Search in Google ScholarBack to article
  26. TRAMONTANO A. C., CHEN Y., WATSON T. R., ECKEL A., SHEEHAN D. F., PETERS M. L. B., et al. Pancreatic cancer treatment costs, including patient liability, by phase of care and treatment modality, 2000–2013. Medicine. 2019;98(49):e18082.
    Search in Google ScholarBack to article
  27. ZENI L. B., RUSSI R. F., FIALHO A. F., FONSECA A. L. P., SOMBRIO L. S., ROCHA I. C. Morbidity and mortality of pancreatic tumors undergoing surgical treatment. Arq Bras Cir Dig. 2014;27(4):275–279.
    Search in Google ScholarBack to article
  28. KOLBEINSSON H. M., CHANDANA S., WRIGHT G. P., CHUNG M. Pancreatic Cancer: A Review of Current Treatment and Novel Therapies. J Invest Surg. 2022;36(1):2129884.
    Search in Google ScholarBack to article
  29. LEVINE I., TRINDADE A. J. Endoscopic ultrasound fine needle aspiration vs fine needle biopsy for pancreatic masses, subepithelial lesions, and lymph nodes. World J Gastroenterol. 2021;27(26):4194–4207.
    Search in Google ScholarBack to article
  30. HASSAN G. M., LAPORTE L., PAQUIN S. C., MENARD C., SAHAI A. V., MÂSSE B., et al. Endoscopic ultrasound guided fine needle aspiration versus endoscopic ultrasound guided fine needle biopsy for pancreatic cancer diagnosis: A systematic review and meta-analysis. Diagnostics. 2022;12(12):2951.
    Search in Google ScholarBack to article
  31. CONSTANTINESCU A., PLOTOGEA O., STAN-ILIE M., CIUREA T., GHEONEA D. I., UNGUREANU B. S., et al. Impact of biliary stenting in endoscopic ultrasound-guided tissue acquisition among patients with pancreatic cancer. J Clin Ultrasound. 2022;50(6):844–849.
    Search in Google ScholarBack to article
  32. SCHAWKAT K., MANNING M. A., GLICKMAN J. N., MORTELE K. J. Pancreatic Ductal Adenocarcinoma and Its Variants: Pearls and Perils. Radiographics. 2020;40(5):1219–1239.
    Search in Google ScholarBack to article
  33. SCHIMA W., BÖHM G., RÖSCH C. S., KLAUS A., FÜGGER R., KOPF H. Mass-forming pancreatitis versus pancreatic ductal adenocarcinoma: CT and MR imaging for differentiation. Cancer Imaging. 2020;20(1).
    Search in Google ScholarBack to article
  34. HERMANOVÁ. M., LENZ J. Differential diagnosis of the chronic pancreatitis and the pancreatic ductal adenocarcinoma. Ceskoslov Patol. 2012;48(3):135–140.
    Search in Google ScholarBack to article
  35. ALDYAB M., JABBOUR T. E., PARILLA M., LEE H. Benign vs malignant pancreatic lesions: Molecular insights to an ongoing debate. World J Gastrointest Surg. 2021;13(5):406–418.
    Search in Google ScholarBack to article
  36. POUW R. E., BARRET M., BIERMANN K., BISSCHOPS R., CZAKÓ L., GECSE K. B., et al. Endoscopic tissue sampling – Part 1: Upper gastrointestinal and hepatopancreatobiliary tracts. European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2021;53(11):1174–1188.
    Search in Google ScholarBack to article
  37. CHUNG M. J., PARK S. W., KIM S., CHO C. M., CHOI J., CHOI E. K., et al. Clinical and Technical Guideline for Endoscopic Ultrasound (EUS)-Guided Tissue Acquisition of Pancreatic Solid Tumor: Korean Society of Gastrointestinal Endoscopy (KSGE). Gut Liver. 2021;15(3):354–374.
    Search in Google ScholarBack to article
DOI: https://doi.org/10.2478/rjim-2025-0008 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749
Journal RSS Feed
Language: English
Page range: 175 - 184
Submitted on: Jan 27, 2025
Published on: Apr 22, 2025
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
accuracy of sampling,
biopsy technique,
endoscopic ultrasound (EUS),
fine-needle aspiration (FNA),
fine-needle biopsy (FNB),
pancreatic cancer
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Internal medicine, other,
Cardiology,
Gastroenterology,
Rheumatology

© 2025 Alexandru Constantinescu, Christopher Pavel, Oana-Mihaela Plotogea, Octavian Andronic, Andreea Pușcașu, Florentina Gherghiceanu, Mădălina Cristina Stan-Ilie, Vasile Șandru, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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