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Association between Bisphenol A exposure and dilated cardiomyopathy Cover

Association between Bisphenol A exposure and dilated cardiomyopathy

Open Access
|Jan 2026

References

  1. Von Goetz N, Wormuth M, Scheringer M, et al. (2010): Bisphenol A: how the most relevant exposure sources contribute to total consumer exposure. Risk Analysis; 30(3):473–487.
  2. Calafat AM, Ye X, Wong LY, et al. (2008): Exposure of the U.S. Population to Bisphenol A and 4-tertiary-Octylphenol: 2003–2004. Environmental Health Perspectives; 116:1 CID: https://doi.org/10.1289/ehp.10753.
  3. Thayer KA, Heindel JJ, Bucher JR, et al. (2012): Role of environmental chemicals in diabetes and obesity: A National Toxicology Program workshop review. Environmental Health Perspectives; 120(6):779–789.
  4. Lang IA, Galloway TS, Scarlett A, et al. (2008): Association of Urinary Bisphenol A Concentration with Medical Disorders and Laboratory Abnormalities in Adults. JAMA; 300(11):1303–1310. https://doi.org/10.1001/jama.300.11.1303.
  5. Melzer D, Rice NE, Lewis C, et al. (2010): Association of urinary bisphenol A concentration with heart disease: evidence from NHANES 2003/06. PlOS ONE; 5(1), e8673. https://doi.org/10.1371/journal.pone.0008673.
  6. Maron BJ, Towbin JA, Thiene G, et al. (2006): Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation; 113(14), 1807–1816. https://doi.org/10.1161/CIRCULATIONAHA.106.174287.
  7. Jefferies JL and Towbin JA. (2010): Dilated cardiomyopathy. The Lancet; 375(9716), 752–762. https://doi.org/10.1016/S0140-6736(09)62023-7.
  8. Xiong Q, Liu X, Shen Y, et al. (2015): Elevated serum Bisphenol A level in patients with dilated cardiomyopathy. International Journal of Environmental Research and Public Health; 12(5):5329-5337. https://doi.org/10.3390/ijerph120505329.
  9. Chan YH. (2003): Biostatistics 102: Quantitative Data - Parametric & Non-parametric Tests. Singapore Medical Journal.; 44(8): 391-396.
  10. Chan YH. (2003): Biostatistics 103: Qualitative Data –Tests of Independence. Singapore Medical Journal.; 44(10): 498-503.
  11. Jager KJ, Zoccali C, Macleod A, et al. (2008): Confounding: what it is and how to deal with it. Kidney International; 73: 256–260.
  12. Wang, H., Liu, Zh., Zhang, J. et al. (2020): Human exposure of bisphenol A and its analogues: understandings from human urinary excretion data and wastewater-based epidemiology. Environmental Science and Pollution Research; 27: 3247–3256. https://doi.org/10.1007/s11356-019-07111-9.
  13. Birnbaum LS, Bucher JR, Collman GW, et al. (2012): Consortium-based science: the NIEHS’s multipronged, collaborative approach to assessing the health effects of bisphenol A. Environmental Health Perspectives; 120 (12):1640–1644.
  14. Posnack, NG, Brooks D, Chandra A, et al. (2015): Physiological response of cardiac tissue to bisphenol A: alterations in ventricular pressure and contractility. American Physiological Society ; 309(2), H267–H275. https://doi.org/10.1152/ajpheart.00272.2015.
  15. Yin-Feng Z, Chan S, Yu w, et al.(2020): cardiovascular toxicity and mechanism of bisphenol A and emerging risk of bisphenol S. Science of the Total Environment. Volume 723,25 June 2020,137952. https://doi. org/10.1016/scitotenv.2020.137952.
  16. Gear, R.; Kendziorski, J.A; Belcher, S.M. Effects of bisphenol A on incidence and severity of cardiac lesions in the NCTR-Sprague-Dawley rat: A CLARITY-BPA study. Toxicology Letters. 2017,275, 123-135.
DOI: https://doi.org/10.2478/rjc-2025-0038 | Journal eISSN: 2734-6382 | Journal ISSN: 1220-658X
Language: English
Published on: Jan 27, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Hassan Mohamed Ebeid, Khaled Ahmed Elkhashab, Naglaa Abdel-Khalek El-Sherbiny, Moustafa Kamal Eldin Ibrahim Khalil Saad, published by Romanian Society of Cardiology
This work is licensed under the Creative Commons Attribution 4.0 License.

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