Figure 1
Figure 2
Figure 3
Figure 4
Demographic and clinical characteristics of the studied population_
| Parameter | All patients (n=7442) | Females (n=2234) | Males (n=5208) | p value |
|---|---|---|---|---|
| In hospital death | 256/7442 (3.44%) | 116/2234 (5.19%) | 140/5208 (2.69%) | 0,0005 |
| Age (years) | 65.04 (57.56 - 71.87) | 67.52 (60.75 - 74.22) | 64.03 (55.76 - 70.74) | <0.0001 |
| BMI (kg/m2) | 28.37 (25.81 - 31.44) | 28.36 (25.39 - 32.03) | 28.37 (25.95 - 31.24) | 0,54415 |
| Prior MI | 1574/7442 (21.15%) | 412/2234 (18.44%) | 1162/5208 (22.31%) | 0,0005 |
| Prior CABG | 201/7442 (2.7%) | 45/2234 (2.01%) | 156/5208 (3%) | 0,01799 |
| Prior PCI | 1902/7442 (25.56%) | 539/2234 (24.13%) | 1363/5208 (26.17%) | 0,07696 |
| Stroke/TIA | 515/7442 (6.92%) | 183/2234 (8.19%) | 332/5208 (6.37%) | 0,008 |
| Atrial fibrillation | 869/7442 (11.68%) | 293/2234 (13.12%) | 576/5208 (11.06%) | 0,0075 |
| Peripheral artery disease | 804/7442 (10.8%) | 200/2234 (8.95%) | 604/5208 (11.6%) | 0,0015 |
| Chronic kidney disease | 569/7442 (7.65%) | 204/2234 (9.13%) | 365/5208 (7.01%) | 0,001 |
| Valvular heart disease | 456/7442 (6.13%) | 173/2234 (7.74%) | 283/5208 (5.43%) | 0,0005 |
| Dilated cardiomyopathy | 628/7442 (8.44%) | 154/2234 (6.89%) | 474/5208 (9.1%) | 0,0015 |
| Chronic heart failure | 863/7442 (11.6%) | 210/2234 (9.4%) | 653/5208 (12.54%) | 0,0005 |
| COPD | 662/7442 (8.9%) | 165/2234 (7.39%) | 497/5208 (9.54%) | 0,0035 |
| Smoking status | 0 (0 - 1) | 0 (0 - 1) | 1 (0 - 1) | <0.0001 |
| Smokers | 3257/7442 (42.07%) | 596/2234 (26.68%) | 2661/5208 (51.09%) | <0.0001 |
| Diabets Mellitus | 1479/7442 (19.87%) | 460/2234 (20.59%) | 1019/5208 (19.57%) | 0,30535 |
| Hypertension | 3872/7442 (52.03%) | 1165/2234 (52.15%) | 2707/5208 (51.98%) | 0,90455 |
| Dyslipidemia | 3025/7442 (40.65%) | 871/2234 (38.99%) | 2154/5208 (41.36%) | 0,04998 |
| LVEF (%) | 50 (40 - 55) | 50 (40 - 55) | 50 (40 - 55) | <0.0001 |
| ICU stay | 346/7442 (4.65%) | 120/2234 (5.37%) | 226/5208 (4.34%) | 0,05497 |
| ACS-STE | 1917/7442 (25.76%) | 611/2234 (27.35%) | 1306/5208 (25.08%) | 0,04498 |
| ACS-NSTEMI | 621/7442 (8.34%) | 196/2234 (8.77%) | 425/5208 (8.16%) | 0,3958 |
| ACS-UA | 1386/7442 (18.62%) | 430/2234 (19.25%) | 956/5208 (18.36%) | 0,3903 |
| CCS | 3518/7442 (47.27%) | 997/2234 (44.63%) | 2521/5208 (48.41%) | 0,003 |
| Time from symptom onset to hospitalization (hours) | 9.69 (5.26 - 21.39) | 10.6 (5.78 - 24.02) | 9.07 (5.13 - 20.68) | 0,03767 |
| Time from hospitalization to PCI (hours) | 24.93 (3.1 - 56.7) | 24.52 (2.51 - 51.14) | 25.08 (3.27 - 62.27) | 0,01517 |
| Time from symptom onset to PCI hours | 17.06 (6.42 - 54.68) | 19.29 (7.8 - 60.31) | 16.16 (6.04 - 47.22) | 0,02729 |
| RCA angioplasty | 0 (0 - 1) | 0 (0 - 1) | 0 (0 - 1) | 0,75875 |
| LAD angioplasty | 0 (0 - 1) | 0 (0 - 1) | 0 (0 - 1) | 0,2436 |
| CXA angioplasty | 0 (0 - 1) | 0 (0 - 0) | 0 (0 - 1) | 0,00241 |
| LM angioplasty | 401/7126 (5.63%) | 130/2146 (6.06%) | 271/4980 (5.44%) | 0,33583 |
| Number of diseased coronary | 2 (1 - 3) | 2 (1 - 3) | 2 (1 - 3) | 0,07018 |
| Proximal segment angioplasty | 3198/7126 (44.88%) | 970/2146 (45.2%) | 2228/4980 (44.74%) | 0,73663 |
| Segments treated | 1 (1 - 2) | 1 (1 - 2) | 1 (1 - 2) | 0,14471 |
| TIMI pre PCI | 2 (0 - 3) | 2 (0 - 3) | 2 (0 - 3) | 0,49294 |
| TIMI post PCI | 3 (3 - 3) | 3 (3 - 3) | 3 (3 - 3) | 0,89929 |
| Complete revascularization | 2532/6950 (36.43%) | 800/2084 (38.39%) | 1732/4866 (35.59%) | 0,03298 |
| Radial vascular access | 5669/7442 (76.18%) | 1641/2234 (73.46%) | 4028/5208 (77.34%) | 0,0015 |
| Vascular closure device | 477/7442 (6.41%) | 178/2234 (7.97%) | 299/5208 (5.74%) | 0,001 |
| Cardiogenic shock | 171/7442 (2.3%) | 72/2234 (3.22%) | 99/5208 (1.9%) | 0,0015 |
| CPR during hospitalization | 183/7442 (2.46%) | 82/2234 (3.67%) | 101/5208 (1.94%) | 0,0005 |
| Hospitalization days | 5.3 (3.8 - 7.2) | 5.5 (3.8 - 7.5) | 5.2 (3.8 - 7.1) | 0,08437 |
| CK MB U L Max | 45 (23 - 165) | 52 (25 - 171.25) | 43 (23 - 161) | 0,00979 |
| Total cholesterol (mg/dL) | 166 (136 - 203) | 174 (144 - 211) | 163 (134 - 200) | <0.0001 |
| HDL cholesterol (mg/dL) | 36 (30 - 42) | 39 (32 - 45.62) | 34 (29 - 41) | <0.0001 |
| LDL cholesterol (mg/dL) | 97 (74 - 129) | 102 (79 - 136) | 96 (71 - 126) | <0.0001 |
| Triglyceride (mg/dL) | 127 (93 - 182) | 128 (95 - 181) | 127 (91.68 - 183) | 0,80268 |
| Creatinine (mg/dL) | 0.91 (0.79 - 1.1) | 0.82 (0.73 - 1.02) | 0.94 (0.83 - 1.11) | <0.0001 |
| CrCl (ml/min) | 77.04 (58.23 - 93.36) | 68.67 (45.44 - 81.32) | 82.97 (63.28 - 97.71) | <0.0001 |
| Hemoglobin (g/dL) | 13.5 (12.4 - 14.57) | 12.5 (11.45 - 13.4) | 14 (12.9 - 14.85) | <0.0001 |
| Platelets (×103/μL) | 224 (187 - 267.3) | 238 (196 - 281) | 219 (183 - 260) | <0.0001 |
| WBC (×103/μL) | 8.14 (6.73 - 9.94) | 8.04 (6.58 - 9.91) | 8.18 (6.79 - 9.95) | 0,01384 |
| LDH (U/L) | 204 (164 - 355.81) | 218 (174 - 379.16) | 200 (161 - 344.55) | <0.0001 |
| PCR (mg/dL) | 1.69 (0.39 - 8.1) | 1.72 (0.44 - 6.88) | 1.68 (0.37 - 8.64) | 0,95628 |
| Tronopine (ng/L) | 0.94 (0.05 - 92.9) | 2 (0.05 - 132.75) | 0.63 (0.05 - 58.83) | 0,28548 |
| NTproBNP (pg/ml) | 963 (212 - 2897) | 1100 (327 - 3615) | 876.5 (181.25 - 2574) | 0,04279 |
| SYNTAX score | 16 (9 - 25) | 16 (9 - 25.5) | 16 (9 - 24.5) | 0,70737 |
| ACEF score | 1.35 (1.13 - 1.68) | 1.38 (1.16 - 1.72) | 1.33 (1.12 - 1.66) | <0.0001 |
| GRACE score | 86.41 (72.97 - 101.09) | 90.18 (78.1 - 105.6) | 84.72 (70.65 - 98.9) | <0.0001 |