
Figure 1
The ECG parameters measurement.

Figure 2
Schematic representation of the study protocol.

Figure 3
Heart rate in control rats and in rats exposed to human relevant (BPA) and supraphysiological (hBPA) bisphenol A doses for 7 consecutive weeks. Data are expressed as median and interquartile ranges; p-values were calculated using the Kruskal–Wallis and the Mann–Whitney U tests. * The p-value refers to the comparison between groups based on the Kruskal–Wallis test; ** the p-value refers to the comparison between the control and hBPA groups based on the Mann–Whitney test.

Figure 4
ECG parameters in control rats and in rats exposed to usual (BPA) and high (hBPA) bisphenol A doses for 7 weeks. The figure illustrates the duration of the P wave (A) and the QRS complex (B).Data are expressed as median and interquartile ranges; p-values were calculated using the Kruskal–Wallis and the Mann–Whitney U tests. * The p-value refers to the comparison between groups based on the Kruskal–Wallis test; ** the p-value refers to the comparison between the Control and hBPA groups based on the Mann–Whitney test.

Figure 5
The duration of the PQ segment (ms). Data are expressed as median and interquartile ranges; p-values were calculated using the Kruskal–Wallis and the Mann–Whitney U tests. * The p-value refers to the comparison between groups based on the Kruskal–Wallis test; ** the p-value refers to the comparison between the Control and hBPA groups based on the Mann–Whitney test.

Figure 6
ECG parameters in control rats and in rats exposed to usual (BPA) and high (hBPA) bisphenol A doses for 7 weeks. The figure illustrates the duration of the ST segment (A) and the T wave (B). Data are expressed as median and interquartile ranges; p-values were calculated using the Kruskal–Wallis and the Mann–Whitney U tests. * The p-value refers to the comparison between groups based on the Kruskal–Wallis test; ** the p-value refers to the comparison between the Control and hBPA groups based on the Mann–Whitney test.

Figure 7
The duration of the QT interval (ms). Data are expressed as median and interquartile ranges; p-values were calculated using the Kruskal–Wallis and the Mann–Whitney U tests. * The p-value refers to the comparison between groups based on the Kruskal–Wallis test; ** the p-value refers to the comparison between the Control and hBPA groups based on the Mann–Whitney test.