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Ironing Out the Link: Ferritin and Coronary Artery Disease- a Two-year Perspective on Disease Burden and Prognosis Cover

Ironing Out the Link: Ferritin and Coronary Artery Disease- a Two-year Perspective on Disease Burden and Prognosis

Open Access
|Mar 2025

Figures & Tables

Table 1

Baseline data.

Mean Age (in years)59.03 ± 9.42
SexMale215 (71.66%)
Female85 (28.33%)
Hypertension155 (51.66%)
Diabetes106 (35.33%)
PresentationACS150 (50%)
CCS150 (50%)
Mean Haemoglobin Level (g/dl)12.30 ± 1.53
Mean Creatinine Level (mg/dl)0.96 ± 0.24
Mean Ferritin Level (μg/L)98.09 ± 96.17
Ferritin LevelsHIGH24 (8%)
NORMAL188 (62.7%)
LOW88 (29.3%)
CAD BurdenNON-CRITICAL CAD52 (17.3%)
SINGLE VESSEL DISEASE96 (32%)
DUAL VESSEL DISEASE92 (30.7%)
TRIPLE VESSEL DISEASE60 (20%)
StatusALIVE240 (80%)
DEAD40 (13.3%)
LOSS TO FOLLOW UP20 (6.7%)
Table 2

Correlation and association of ferritin with other variables

ParameterCorrelation/AssociationStatistical Significance
Correlation with Ferritin
AgeCorrelation Coefficient: -0.122(P = 0.035)*
Hemoglobin (Hb)Correlation Coefficient: 0.147(P = 0.011)*
CreatinineCorrelation Coefficient: 0.281(P = 0.001)*
Association with Ferritin Levels
SexChi-square = 22.2306(P = 0.001)*
ACS vs CCSChi-square = 17.696(P = 0.001)*
Hypertension (HTN)Chi-square = 2.518(P = 0.284)
Diabetes Mellitus (DM)Chi-square = 2.359(P = 0.307)
CAD BURDENChi-square = 13.118(P = 0.041)*
Mortality StatusChi-square = 34.903(P = 0.001)*

1 ACS-Acute coronary syndrome, CCS-Chronic coronary syndrome, CAD-Coronary Artery Disease,

1* =P value <0.05 is significant

Table 3

Association of survival outcomes with other variables

ParameterAliveDeadTotalChi-squareP-value
Sex0.1930.661
Female64 (26.7%)12 (30.0%)76 (27.1%)
Male176 (73.3%)28 (70.0%)204 (72.9%)
Diagnosis0.0380.845
ACS124 (51.7%)20 (50.0%)144 (51.4%)
CCS116 (48.3%)20 (50.0%)136 (48.6%)
Hypertension (HTN)12.430.001*
No HTN120 (50.0%)8 (20.0%)128 (45.7%)
With HTN120 (50.0%)32 (80.0%)152 (54.3%)
Diabetes Mellitus (DM)10.440.001*
No DM160 (66.7%)16 (40.0%)176 (62.9%)
With DM80 (33.3%)24 (60.0%)104 (37.1%)
Age58.25 ± 9.6565.10 ± 9.264.1810.001*
Hemoglobin (Hb)12.42 ± 1.5512.09 ± 1.631.2270.221
Creatinine0.95 ± 0.251.03 ± 0.20-1.8260.069
Mean Ferritin Levels90.45 ± 86.11142.00 ± 131.77-3.2160.001*
CAD Burden11.070.011*
Dual Vessel Disease64 (26.7%)20 (50.0%)84 (30.0%)
Non-Critical CAD40 (16.7%)8 (20.0%)48 (17.1%)
Single Vessel Disease88 (36.7%)8 (20.0%)96 (34.3%)
Triple Vessel Disease48 (20.0%)4 (10.0%)52 (18.6%)
Ferritin Level30.690.001*
High12 (5.0%)12 (30.0%)24 (8.6%)
Low76 (31.7%)4 (10.0%)80 (28.6%)
Normal152 (63.3%)24 (60.0%)176 (62.9%)

1 ACS-Acute coronary syndrome, CCS-Chronic coronary syndrome, CAD-Coronary Artery Disease,

1* = P value <0.05 is significant

DOI: https://doi.org/10.2478/rjc-2025-0011 | Journal eISSN: 2734-6382 | Journal ISSN: 1220-658X
Language: English, Romanian
Page range: 52 - 58
Published on: Mar 31, 2025
Published by: Romanian Society of Cardiology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Soumik Ghosh, Rajpal Prajapati, Chandra Kishore, Amit Kumar Gauraw, Arjun Tandon, published by Romanian Society of Cardiology
This work is licensed under the Creative Commons Attribution 4.0 License.