Evaluation of Peripheral Vascular Function After Distal Radial Artery Access for Invasive Percutaneous Coronary Procedures

Ungureanu, Claudiu; Dumitrascu, Silviu; Colletti, Giuseppe; Blaimont, Marc; Mignon, Manuel; van de Borne, Philippe

doi:10.2478/rjc-2022-0028

Abstract

Objective: The aim of this study is to investigate the difference in impact between distal transradial access (dTRA) and classical transradial access (TRA) on vascular function using flow-mediated vasodilation (FMD) following coronary diagnostic and therapeutic catheterizations.

Methods: The analysis involves a non-randomized inclusion of patients undergoing either diagnostic or elective percutaneous coronary intervention, using a dTRA access or a conventional standard TRA. Two hours after the procedure ended, the endothelium-dependent flow-mediated dilation of the brachial artery was measured by ultrasound.

Results: A total number of 50 patients were included. There was no statistically significant difference between the two groups (7.20% vs 6.99%, p < 0.09 for non-inferiority). Additionally, there were higher baseline values observed for BA diameters in the conventional approach group.

Regarding the other secondary endpoints, there were no major access site complications, radial occlusion, in-hospital major bleeding or severe arterial spasm recorded in both groups.

Conclusion: Compared to conventional TRA, accessing distal radial artery for diagnostic and therapeutic coronary interventions has the same impact on short-term vascular endothelial function and was safely performed without any major vascular complications.

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Evaluation of Peripheral Vascular Function After Distal Radial Artery Access for Invasive Percutaneous Coronary Procedures

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