Correlation of quiescent-interval single-shot (QISS) magnetic resonance angiography (MRA), computed tomography angiography (CTA) and digital subtraction angiography (DSA) for peripheral arterial disease (PAD) assessment
By: Silva Breznik, Ales Slanic and Jernej Lucev
References
- Song P, Rudan D, Zhu Y, Fowkes FJI, Rahimi K, Fowkes FGR, et al. Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: an updated systematic review and analysis. Lancet Glob Health 2019; 7: e1020-e30. doi: 10.1016/S2214-109X(19)30255-4
- Criqui MH, Aboyans V. Epidemiology of peripheral artery disease. Circ Res 2015; 116: 1509-26. doi: 10.1161/CIRCRESAHA.116.303849 Erratum in: Circ Res 2015; 117: e12. doi: 10.1161/res.0000000000000059
- Resnick HE, Lindsay RS, McDermott MM, Devereux RB, Jones KL, Fabsitz RR, et al. Relationship of high and low ankle brachial index to all-cause and cardiovascular disease mortality: the Strong Heart Study. Circulation 2004; 109: 733-9. doi: 10.1161/01.cir.0000112642.63927.54
- Edelman RR, Carr M, Koktzoglou I. Advances in non-contrast quiescent-interval slice-selective (QISS) magnetic resonance angiography. Clin Radiol 2019; 74: 29-36. doi: 10.1016/j.crad.2017.12.003
- Varga-Szemes A, Penmetsa M, Emrich T, Todoran TM, Suranyi P, Fuller SR, et al. Diagnostic accuracy of non-contrast quiescent-interval slice-selective (QISS) MRA combined with MRI-based vascular calcification visualization for the assessment of arterial stenosis in patients with lower extremity peripheral artery disease. Eur Radiol 2021; 31: 2778-87. doi: 10.1007/s00330-020-07386-4
- Ouwendijk R, de Vries M, Stijnen T, Pattynama PM, van Sambeek MR, Buth J, et al. Multicenter randomized controlled trial of the costs and effects of noninvasive diagnostic imaging in patients with peripheral arterial disease: the DIPAD trial. AJR Am J Roentgenol 2008; 190: 1349-57. doi: 10.2214/AJR.07.3359
- Davenport MS, Perazella MA, Yee J, Dillman JR, Fine D, McDonald RJ, et al. Use of intravenous iodinated contrast media in patients with kidney disease: consensus statements from the American College of Radiology and the National Kidney Foundation. Radiology 2020; 294: 660-8. doi: 10.1148/radiol.2019192094
- Carr JC. QISS MR Angiography: an alternative to CT angiography for peripheral vascular evaluation. JACC Cardiovasc Imaging 2017; 10: 1125-7. doi: 10.1016/j.jcmg.2016.11.012
- Collins R, Burch J, Cranny G, Aguiar-Ibáñez R, Craig D, Wright K, et al. Duplex ultrasonography, magnetic resonance angiography, and computed tomography angiography for diagnosis and assessment of symptomatic, lower limb peripheral arterial disease: systematic review. BMJ 2007; 334: 1257. doi: 10.1136/bmj.39217.473275.55
- Wicky S, Pinto EG, Oklu R. Catheter-directed thrombolysis of arterial thrombosis. Semin Thromb Hemost 2013; 39: 441-5. doi: 10.1055/s-0033-1334482
- Edelman RR, Sheehan JJ, Dunkle E, Schindler N, Carr J, Koktzoglou I. Quiescent-interval single-shot unenhanced magnetic resonance angiography of peripheral vascular disease: technical considerations and clinical feasibility. Magn Reson Med 2010; 63: 951-8. doi: 10.1002/mrm.22287
- Varga-Szemes A, Wichmann JL, Schoepf UJ, Suranyi P, De Cecco CN, Muscogiuri G, et al. Accuracy of noncontrast quiescent-interval single-shot lower extremity MR angiography versus CT angiography for diagnosis of peripheral artery disease: comparison with digital subtraction angiography. JACC Cardiovasc Imaging 2017; 10: 1116-24. doi: 10.1016/j.jcmg.2016.09.030
- Verma M, Pandey NN, Singh V, Jagia P. A meta-analysis of the diagnostic performance of quiescent-interval-single-shot magnetic resonance angiography in peripheral arterial disease. Eur Radiol 2022; 32: 2393-403. doi: 10.1007/s00330-021-08349-z
- Varga-Szemes A, Aouad P, Schoepf UJ, Emrich T, Yacoub B, Todoran TM, et al. Comparison of 2D and 3D quiescent-interval slice-selective non-contrast MR angiography in patients with peripheral artery disease. MAGMA 2021; 34: 649-58. doi: 10.1007/s10334-021-00927-y
- Yamamoto Y, Ishikawa Y, Shimpo M, Matsumura M. Mönckeberg’s sclerosis. J Gen Fam Med 2020; 22: 55-6. doi: 10.1002/jgf2.380
- Lebenatus A, Tesch K, Rudolph W, Naujokat H, Koktzoglou I, Edelman RR, et al. Evaluation of lower leg arteries and fibular perforators before microsurgical fibular transfer using noncontrast-enhanced quiescent-interval slice-selective (QISS) magnetic resonance angiography. J Clin Med 2023; 12: 1634. doi: 10.3390/jcm12041634
- Saini A, Wallace A, Albadawi H, Naidu S, Alzubaidi S, Knuttinen MG, et al. Quiescent-interval single-shot magnetic resonance angiography. Diagnostics (Basel) 2018; 8: 84. doi: 10.3390/diagnostics8040084
- Gutzeit A, Sutter R, Froehlich JM, Roos JE, Sautter T, Schoch E, et al. ECG-triggered non-contrast-enhanced MR angiography (TRANCE) versus digital subtraction angiography in patients with peripheral arterial occlusive disease of the lower extremities. Eur Radiol 2011; 21: 1979-87. doi: 10.1007/s00330-011-2132-4
- Ghibes P, Partovi S, Artzner C, Grözinger G, Wahl CM, Hagen F, et al. Noncontrast MR angiography of pelvic arterial vasculature using the quiescent interval slice selective (QISS) sequence. Int J Cardiovasc Imaging 2023; 39: 1023-30. doi: 10.1007/s10554-023-02798-x
- Wu G, Yang Y, Liu L. The effect of non-contrast enhanced MRA on patients with renal insufficiency and foot pain. Medicine (Baltimore) 2023; 102: e36372. doi: 10.1097/MD.0000000000036372
- Salehi Ravesh M, Lebenatus A, Bonietzki A, Hensler J, Koktzoglou I, et al. High-resolution, non-contrast-enhanced magnetic resonance angiography of the wrist, hand and digital arteries using optimized implementation of Cartesian quiescent interval slice selective (QISS) at 1.5 T. Magn Reson Imaging 2021; 78: 58-68. doi: 10.1016/j.mri.2021.02.008
- Panda A, Francois CJ, Bookwalter CA, Chaturvedi A, Collins JD, Leiner T, et al. Non-contrast magnetic resonance angiography: techniques, principles, and applications. Magn Reson Imaging Clin N Am 2023; 31: 337-60. doi: 10.1016/j.mric.2023.04.001
Language: English
Submitted on: Nov 7, 2025
Accepted on: Feb 16, 2026
Published on: Apr 16, 2026
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2026 Silva Breznik, Ales Slanic, Jernej Lucev, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.