Intrathoracic extramedullary haematopoiesis mimicking pulmonary malignancy in two patients with thalassaemia: A case series
References
- Galanello R, Origa R. Beta-thalassemia. Orphanet Journal of Rare Diseases. 2010;5: 11. doi:10.1186/1750-1172-5-11.
- Taher AT, Musallam KM, Cappellini MD. β-thalassemias. New England Journal of Medicine. 2021;384(8): 727–743. doi:10.1056/NEJMra2021838.
- Haidar R, Mhaidli H, Taher AT. Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia. European Spine Journal. 2010;19(6): 871–878. doi:10.1007/s00586-010-1357-2.
- Georgiades CS, Neyman EG, Francis IR, Sneider MB, Fishman EK. Typical and atypical presentations of extramedullary hemopoiesis. AJR. American Journal of Roentgenology. 2002;179(5): 1239–1243. doi:10.2214/ajr.179.5.1791239.
- Hassanzadeh M. Images in clinical medicine. Extramedullary hematopoiesis in thalassemia. New England Journal of Medicine. 2013;369(13): 1252. doi:10.1056/NEJMicm1303084.
- Bobylev D, Zhang R, Haverich A, Krueger M. Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia. Journal of Cardiothoracic Surgery. 2013;8: 120. doi:10.1186/1749-8090-8-120.
- An J, Weng Y, He J, Li Y, Huang S, Cai S, et al. Intrathoracic extramedullary hematopoiesis presenting as tumor-simulating lesions of the mediastinum in alpha-thalassemia: a case report. Oncology Letters. 2015;10(4): 1993–1996. doi:10.3892/ol.2015.3597.
- Bowling MR, Cauthen CG, Perry CD, Patel NP, Bergman S, Link KM, et al. Pulmonary extramedullary hematopoiesis. Journal of Thoracic Imaging. 2008;23(2): 138–141. doi:10.1097/RTI.0b013e31815b89aa.
- Hosseinzadeh M, Omidifar N, Kumar PV, Rasekhi A. Pulmonary extramedullary hematopoiesis in a patient with chronic asthma resembling lung cancer: a case report. Case Reports in Medicine. 2012;2012: 231787. doi:10.1155/2012/231787.
- Fujimoto A, Hamaguchi S, Suzuki R. Case of pulmonary extramedullary hematopoiesis responding to ruxolitinib. Leukemia Research Reports. 2022;17: 100290. doi:10.1016/j.lrr.2022.100290.
- Singh I, Mikita G, Green D, Risquez C, Sanders A. Pulmonary extra-medullary hematopoiesis and pulmonary hypertension from underlying polycythemia vera: a case series. Pulmonary Circulation. 2017;7(1): 261–267. doi:10.1177/2045893217702064.
- Cario H, Wegener M, Debatin KM, Kohne E. Treatment with hydroxyurea in thalassemia intermedia with paravertebral pseudotumors of extramedullary hematopoiesis. Annals of Hematology. 2002;81(8): 478–482. doi:10.1007/s00277-002-0501-4.
- Meo A, Cassinerio E, Castelli R, Bignamini D, Perego L, Cappellini MD. Effect of hydroxyurea on extramedullary haematopoiesis in thalassaemia intermedia: case reports and literature review. International Journal of Laboratory Hematology. 2008;30(5): 425–431. doi:10.1111/j.1751-553X.2007.00965.x.
Language: English, Romanian
Page range: 134 - 139
Published on: Sep 29, 2026
Published by: Romanian Society of Pneumology
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open
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© 2026 Kevin Aristyo, Arini Purwono, Dea Putri Audina, Ginanjar Arum Desianti, Tina Reisa, Hayatun Nufus, Jamal Zaini, Fariz Nurwidya, Eylin Rahardjo, Mia Elhidsi, published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.