Clinical impact of structured weight reduction on muscle mass in COPD with sarcopenic obesity

	Group A	Group B
	Mean ± SD	Mean ± SD	MD	t-value	P-value
Age (years)	55.28 ± 4.67	55.76 ± 4.50	−0.48	−0.37	0.71
Weight (kg)	94.18 ± 4.65	94.56 ± 4.30	−0.38	−0.31	0.76
Height (cm)	170.00 ± 2.99	169.88 ± 3.13	0.12	0.14	0.89
BMI (kg/m²)	31.53 ± 0.98	31.72 ± 1.03	−0.19	−0.66	0.51

1 BMI, body mass index; MD, mean difference, P-value, probability value; SD, standard deviation.

Table 2.

Mean weight and BMI pre- and post-treatment of group A and B

	Pre treatment	Post treatment
	Mean ± SD	Mean ± SD	MD	% of change	P-value
Weight (kg)
Group A	94.18 ± 4.65	84.70 ± 3.07	9.48	10.07	0.001
Group B	94.56 ± 4.30	87.97 ± 4.11	6.59	6.97	0.001
MD	−0.38	−3.27
	*P = 0.76*	*P = 0.003*
BMI (kg/m²)
Group A	31.53 ± 0.98	29.31 ± 0.97	2.22	7.04	0.001
Group B	31.72 ± 1.03	30.48 ± 1.23	1.24	3.91	0.001
MD	−0.19	−1.17
	*P = 0.51*	*P = 0.001*

1 Indicate statistically significant difference between groups.

BMI, body mass index; MD, mean difference; P-value, probability value; SD, standard deviation.

Table 3.

Mean SMM, SMMI, HGS and 6MWT pre- and post-treatment of group A and B

	Pre-treatment	Post-treatment
	Mean ± SD	Mean ± SD	MD	% of change	P-value
SMM (kg)
Group A	28.31 ± 1.65	30.45 ± 2.05	−2.14	7.56	0.001
Group B	28.69 ± 1.92	28.65 ± 1.92	0.04	0.14	0.81
MD	−0.38	1.8
	*P = 0.46*	*P = 0.002*
SMMI
Group A	9.79 ± 0.49	10.53 ± 0.61	−0.74	7.56	0.001
Group B	9.94 ± 0.59	9.93 ± 0.59	0.01	0.10	0.81
MD	−0.15	0.6
	*P = 0.35*	*P = 0.001*
Hand grip strength (kg)
Group A	23.20 ± 2.81	34.12 ± 2.74	−10.92	47.07	0.001
Group B	24.32 ± 2.50	31.12 ± 1.86	−6.8	27.96	0.001
MD	−1.12	3
	*P = 0.14*	*P = 0.001*
6MWT (m)
Group A	286.64 ± 12.24	328.80 ± 15.78	−42.16	14.71	0.001
Group B	288.28 ± 11.34	307.84 ± 11.99	−19.56	6.79	0.001
MD	−1.64	20.96
	*P = 0.63*	*P = 0.001*

1 Indicate statistically significant difference between groups.

HGS, handgrip strength; MD, mean difference; P-value, probability value; SD, standard deviation; SMM, skeletal muscle mass; SMMI, skeletal muscle mass index.

References

Authors

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Articles in this issue

DOI: https://doi.org/10.2478/pneum-2026-0010 | Journal eISSN: 2247-059X | Journal ISSN: 2067-2993

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Language: English, Romanian

Page range: 68 - 76

Published on: Jul 22, 2026

Published by: Romanian Society of Pneumology

In partnership with: Paradigm Publishing Services

Publication frequency: Volume open

Keywords:

weight reduction,

sarcopenic obesity,

COPD,

SMM,

handgrip and 6MWDT

Related subjects:

Medicine,

Clinical medicine,

Clinical medicine, other,

Internal medicine,

Pneumology

© 2026 Alaa Magdy Mostafa, Karim Ahmed, Mahmoud Mohamed El batanouny, Lamis Ahmed Osama Ghaly, published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 75 (2026): Issue 1 (January 2026)