Skip to main content
Have a personal or library account? Click to login
Factors Affecting Quality of Honey Bee Venom Cover

Factors Affecting Quality of Honey Bee Venom

Journal of Apicultural Science
Volume 66 (2022): Issue 1 (June 2022)
By: Meral Kekeçoğlu,  Tuğçe Çaprazlı,  Aslı E. Tanuğur Samancı,  Taylan Samancı and  Elif Yorulmaz Önder  
Open Access
|Jun 2022
References

References

  1. Abdela, N., & Jilo., K. (2016). Bee venom and its therapeutic values: a review. Advances in Life Science and Technology, 44, 18–22.
    Search in Google ScholarBack to article
  2. Abusabbah, M., Hong Lau, W., Mahmoud, M. E. E., Salih, A. M., Omar, D. (2016). Prospects of using carbohydrates as supplemented-diets and protein rich mixture as alternative-diet to improve the quality of venom produced by Apis cerana L. Journal of Entomology and Zoology Studies, 4(3), 23–26.
    Search in Google ScholarBack to article
  3. Ali, M. A. (2012). Studies on bee venom and its medical uses. International Journal of Advanced Research in Science, 1(2), 69–83.
    Search in Google ScholarBack to article
  4. Bachmayer, H., Kreil, G., Suchanek, G. (1972). Synthesis of promelittin and melittin in the venom gland of queen and worker bees: patterns observed during maturation. Journal of Insect Physiology, 18, 1515–1521. DOI: 10.1016/0022-1910(72)90230-2
    BachmayerH. KreilG. SuchanekG. 1972 Synthesis of promelittin and melittin in the venom gland of queen and worker bees: patterns observed during maturation Journal of Insect Physiology 18 1515 1521 10.1016/0022-1910(72)90230-2
    Open DOIBack to article
  5. Baher, W., & Abo Zeid, A. A. (2017). Theneuroprotective effect of bee venom against diabetic neuropathy in a rat model: ultrastructure and morphometric study. European Journal of Pharmaceutical and Medical Research, 4(8), 50–59.
    Search in Google ScholarBack to article
  6. Banks, B. E. C., & Shipolini, R. A. (1986). Chemistry and pharmacology of honey-bee venom., In Piek, T (ed.) Venoms of the Hymenoptera, Academic Press; London; 330–416.
    Search in Google ScholarBack to article
  7. Bogdanov, S. (2012). Bee venom: composition, health, medicine: A review. Peptides, 1–16.
    Search in Google ScholarBack to article
  8. Bogdanov, S. (2015). The bee venom book, Chapter 1. Switzerland: Muehlethurnen.
    Search in Google ScholarBack to article
  9. Eze, O. B. L., Nwodo, O. F. C., Ogugua, V. N. (2016). Therapeutic effect of honey bee venom. Journal of Pharmaceutical, Chemical and Biological Sciences, 4(1), 48–53.
    Search in Google ScholarBack to article
  10. Ferreira Junior, R. S., Sciani, J. M., Marques-Porto, R., Lourenço, A., Orsi, R. D. O., Barraviera, B., Pimenta, D. C. (2010). Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A2 levels. Toxicon, 56(3), 355–362. DOI: 10.1016/j.toxicon.2010.03.023
    Ferreira JuniorR. S. ScianiJ. M. Marques-PortoR. LourençoA. OrsiR. D. O. BarravieraB. PimentaD. C. 2010 Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A2 levels Toxicon 56 3 355 362 10.1016/j.toxicon.2010.03.023 20403370
    Open DOIBack to article
  11. Gajski, G., & Garaj-Vrhovac, V. (2009). Radioprotective effects of honeybee venom (Apis mellifera) against 915-MHz microwave radiation-induced DNA damage in Wistar rat lymphocytes: In vitro study. International Journal of Toxicology, 28(2), 88–98. DOI: 10.1177/1091581809335051
    GajskiG. Garaj-VrhovacV. 2009 Radioprotective effects of honeybee venom (Apis mellifera) against 915-MHz microwave radiation-induced DNA damage in Wistar rat lymphocytes: In vitro study International Journal of Toxicology 28 2 88 98 10.1177/1091581809335051 19482833
    Open DOIBack to article
  12. Ghany Zidan, H. A., Mostafa, Z. K., Ibrahim, M. A., Haggag, S. I., Darwish, D. A., Elfiky A. A. (2018). Venom composition of Egyptian and Carniolan honeybee, Apis mellifera L. affected by collection methods. Egyptian Academic Journal of Biological Sciences, 11(4), 59–71. DOI: 10.21608/EAJBSA.2018.17733
    Ghany ZidanH. A. MostafaZ. K. IbrahimM. A. HaggagS. I. DarwishD. A. ElfikyA. A. 2018 Venom composition of Egyptian and Carniolan honeybee, Apis mellifera L. affected by collection methods Egyptian Academic Journal of Biological Sciences 11 4 59 71 10.21608/EAJBSA.2018.17733
    Open DOIBack to article
  13. Haggag, S. I., Al-Fattah, M. A. A., Ewies, M. A., El-Feel, M. A. (2015). Effect of honeybee venom collection from different races on honey area. Academic Journal of Entomology, 8(4), 190–192. DOI: 10.5829/idosi.aje.2015.8.4.10242
    HaggagS. I. Al-FattahM. A. A. EwiesM. A. El-FeelM. A. 2015 Effect of honeybee venom collection from different races on honey area Academic Journal of Entomology 8 4 190 192 10.5829/idosi.aje.2015.8.4.10242
    Open DOIBack to article
  14. Han, S.-M., Lee, K.-G., Yeo, J.-H., Kweon, H.-Y., Woo, S.-O., Lee, M.-L., Lee, M.-Y., Kim, C.-G. (n.d.). Device for Collecting Bee Venom. WIPO Patent WO2007037566A1
    Search in Google ScholarBack to article
  15. Hussein, A., El-Ansari, M., Zahra, A. (2019). Effect of the honeybee hybrid and geographic location on the honey bee venom production. Journal of Plant Protection and Pathology, 10(3), 171–176. DOI: 10.21608/jppp.2019.40922
    HusseinA. El-AnsariM. ZahraA. 2019 Effect of the honeybee hybrid and geographic location on the honey bee venom production Journal of Plant Protection and Pathology 10 3 171 176 10.21608/jppp.2019.40922
    Open DOIBack to article
  16. Hwang, D. S., Kim, S. K., Bae, H. (2015). Therapeutic effects of bee venom on immunological and neurological diseases. Toxins, 7(7), 2413–2421. DOI: 10.3390/toxins7072413
    HwangD. S. KimS. K. BaeH. 2015 Therapeutic effects of bee venom on immunological and neurological diseases Toxins 7 7 2413 2421 10.3390/toxins7072413 451692026131770
    Open DOIBack to article
  17. Ionete, R. E., Dinca, O. R., Tamaian, R., Geana, E. I. (2013). Exploring Apis mellifera venom compounds using highly efficient methods. Progress of Cryogenics and Isotopes Separation, 16(2), 89–100.
    Search in Google ScholarBack to article
  18. Kader, A. A., Azmy, R., Maher, E. A., El Sayed, B. B., Khalil, A. S., Ghalwash, M., Mahmoud, M. (2019). Assessment of bee venom therapy in animal model of statin-induced myopathy. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 55, 71. DOI: 10.1186/s41983-019-0120-9
    KaderA. A. AzmyR. MaherE. A. El SayedB. B. KhalilA. S. GhalwashM. MahmoudM. 2019 Assessment of bee venom therapy in animal model of statin-induced myopathy The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 55 71 10.1186/s41983-019-0120-9
    Open DOIBack to article
  19. Kekeçoğlu, M., Çaprazlı, T., Samancı, T., Tanuğur Samancı, A. E., Yorulmaz Önder, E. (2019). Determination and comparison of apitherapeutic value of Turkish and Chinese bee venom through chemical content analysis. Proceedings Book of 5th International Eurasian Congress on Natural Nutrition, Healthy Life & Sport, 02–06 October 2019, 1133–1139.
    Search in Google ScholarBack to article
  20. Kim, H. W., Kwon, Y. B., Ham, T. W., Roh, D. H., Yoon, S. Y., Lee, H. J., … Lee, J. H. (2003). Acupoint stimulation using bee venom attenuates formalin-induced pain behavior and spinal cord fos expression in rats. The Journal of Veterinary Medical Science, 65(3), 349–355. DOI: 10.1292/jvms.65.349
    KimH. W. KwonY. B. HamT. W. RohD. H. YoonS. Y. LeeH. J. LeeJ. H. 2003 Acupoint stimulation using bee venom attenuates formalin-induced pain behavior and spinal cord fos expression in rats The Journal of Veterinary Medical Science 65 3 349 355 10.1292/jvms.65.349 12679565
    Open DOIBack to article
  21. Kim, H., Park, S., Lee, G. (2019). Potential therapeutic applications of bee venom on skin disease and its mechanisms: a literature review. Toxins, 11(7), 1–29. DOI: 10.3390/toxins11070374
    KimH. ParkS. LeeG. 2019 Potential therapeutic applications of bee venom on skin disease and its mechanisms: a literature review Toxins 11 7 1 29 10.3390/toxins11070374 666965731252651
    Open DOIBack to article
  22. Kokot, Z., & Matysiak, J. (2009). Simultaneous Determination of Major Constituents of Honeybee Venom by LC-DAD. Chromatographia, 69, 1401–1405. DOI: 10.1365/s10337-009-1052-9
    KokotZ. MatysiakJ. 2009 Simultaneous Determination of Major Constituents of Honeybee Venom by LC-DAD Chromatographia 69 1401 1405 10.1365/s10337-009-1052-9
    Open DOIBack to article
  23. Kolayli, S., & Keskin, M. (2020). Natural bee products and their apitherapeutic applications. Studies in Natural Products Chemistry, 66, 175–196. DOI: 10.1016/B978-0-12-817907-9.00007-6
    KolayliS. KeskinM. 2020 Natural bee products and their apitherapeutic applications Studies in Natural Products Chemistry 66 175 196 10.1016/B978-0-12-817907-9.00007-6
    Open DOIBack to article
  24. Kurek-Górecka, A., Górecki, M., Rzepecka-Stojko, A., Balwierz, R., Stojko, J. (2020). Bee Products in Dermatology and Skin Care. Molecules, 25(3), 1–17. DOI: 10.3390/molecules25030556
    Kurek-GóreckaA. GóreckiM. Rzepecka-StojkoA. BalwierzR. StojkoJ. 2020 Bee Products in Dermatology and Skin Care Molecules 25 3 1 17 10.3390/molecules25030556
    Open DOIBack to article
  25. Kye-Sung, K., & Ki-Rok, K. (2009). Experimental studies of validation and stability of sweet bee venom using HPLC. Journal of Pharmacopuncture, 12(4), 33–50. DOI: 10.3831/KPI.2009.12.4.033
    Kye-SungK. Ki-RokK. 2009 Experimental studies of validation and stability of sweet bee venom using HPLC Journal of Pharmacopuncture 12 4 33 50 10.3831/KPI.2009.12.4.033
    Open DOIBack to article
  26. Lee, E., Oh, E., Lee, J., Sul, D., Lee, J. (2004). Use of the tail moment of the lymphocytes to evaluate DNA damage in human biomonitoring studies. Toxicological Sciences, 81(1), 121–132. DOI: 10.1093/toxsci/kfh184
    LeeE. OhE. LeeJ. SulD. LeeJ. 2004 Use of the tail moment of the lymphocytes to evaluate DNA damage in human biomonitoring studies Toxicological Sciences 81 1 121 132 10.1093/toxsci/kfh184
    Open DOIBack to article
  27. Mahmoodzadeh, A., Morady, A., Zarrinnahad, H., Pooshang Bagheri, K., Ghasemi-Dehkordi, P., … Shahmorady, H. (2013). Isolating Melittin from bee venom and evaluating its effect on proliferation of gastric cancer cells. Tehran University Medical Journal TUMS Publications, 70(12), 760–767.
    Search in Google ScholarBack to article
  28. Moreno, M., & Giralt, E. (2015). Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan. Toxins, 7(4), 1126–1150. DOI: 10.3390/toxins7041126
    MorenoM. GiraltE. 2015 Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan Toxins 7 4 1126 1150 10.3390/toxins7041126
    Open DOIBack to article
  29. Nowar, E. E. (2016). Venom Glands Parameters, Venom Production and Composition of Honeybee Apis mellifera L. Affected by Substitute Feeding. Middle East Journal of Agriculture Research, 5(4), 596–603.
    Search in Google ScholarBack to article
  30. Owen, D., & Anne, R. (1982). Catecholamines in honey bee (Apis mellifera L.) and various vespid (Hymenoptera) venoms. Toxicon, 20(6), 1075–1084. DOI: 10.1016/0041-0101(82)90110-6
    OwenD. AnneR. 1982 Catecholamines in honey bee (Apis mellifera L.) and various vespid (Hymenoptera) venoms Toxicon 20 6 1075 1084 10.1016/0041-0101(82)90110-6
    Open DOIBack to article
  31. Owen, M. D., Braidwood, J. L., Bridges, A. R. (1974). Age dependent changes in histamine content of venom of queen and worker bees. Journal of Insect Physiology, 23(8), 1031–1035. DOI: 10.1016/0022-1910(77)90131-7
    OwenM. D. BraidwoodJ. L. BridgesA. R. 1974 Age dependent changes in histamine content of venom of queen and worker bees Journal of Insect Physiology 23 8 1031 1035 10.1016/0022-1910(77)90131-7
    Open DOIBack to article
  32. Owen, M. D., & Sloley, B. D. (1988). 5-Hydroxytryptamine in the venom of the honey bee (Apis mellifera): variation with season and with insect age. Toxicon, 26(6), 577–581. DOI: 10.1016/0041-0101(88)90238-3
    OwenM. D. SloleyB. D. 1988 5-Hydroxytryptamine in the venom of the honey bee (Apis mellifera): variation with season and with insect age Toxicon 26 6 577 581 10.1016/0041-0101(88)90238-3
    Open DOIBack to article
  33. Owen, M. D. (1978). Venom replenishment, as indicated by histamine, in honey bee (Apis mellifera) venom. Journal of Insect Physiology, 24(5), 433–437. DOI: 10.1016/0022-1910(78)90086-0
    OwenM. D. 1978 Venom replenishment, as indicated by histamine, in honey bee (Apis mellifera) venom Journal of Insect Physiology 24 5 433 437 10.1016/0022-1910(78)90086-0
    Open DOIBack to article
  34. Owen, M. D., & Pfaff, L., A. (1995). Melittin synthesis in the venom system of the honey bee (Apis mellifera, L.). Pergamon, 33(9), 1181–1188. DOI: 10.1016/0041-0101(95)00054-p
    OwenM. D. PfaffL. A. 1995 Melittin synthesis in the venom system of the honey bee (Apis mellifera, L.) Pergamon 33 9 1181 1188 10.1016/0041-0101(95)00054-p
    Open DOIBack to article
  35. Owen, M. D.; Pfaff, L. A. N.; Reisman, R. E., Wypych, J. (1990). Phospholipase A2 in venom extracts from honey bees (Apis mellifera L.) of different ages. Toxicon, 28(7), 813–820. DOI: 10.1016/S0041-0101(09)80004-4
    OwenM. D. PfaffL. A. N. ReismanR. E. WypychJ. 1990 Phospholipase A2 in venom extracts from honey bees (Apis mellifera L.) of different ages Toxicon 28 7 813 820 10.1016/S0041-0101(09)80004-4
    Open DOIBack to article
  36. Robson, C.H. Bee Venom Collection Apparatus. U.S. Patent US4,739,531, 26 April 1988.
    Search in Google ScholarBack to article
  37. Rybak-Chmielewska H., & Szczęsna, T. (2004). HPLC study of chemical composition of honeybee (Apis mellifera L.) venom. Journal of Apicultural Science, 48(2), 103–109.
    Search in Google ScholarBack to article
  38. Samanci, T., & Kekeçoğlu, M. (2019). Comparison of commercial and anatolian bee venom in terms of chemical composition. Uludag Bee Journal, 19(1), 61–68. DOI: 10.31467/uluaricilik.527986
    SamanciT. KekeçoğluM. 2019 Comparison of commercial and anatolian bee venom in terms of chemical composition Uludag Bee Journal 19 1 61 68 10.31467/uluaricilik.527986
    Open DOIBack to article
  39. Serrinha, V., Correia, S. D., Marques, G. (2019). Productivity and economic analysis of a new intensive collector in the Portuguese market with implication of open innovation perspective. Journal of Open Innovation: Technology, Market, and Complexity, 5(3), 1–18.
    Search in Google ScholarBack to article
  40. Son, D. J., Lee, J. W., Lee, Y. H., Song, H. S., Lee, C. K., Hong, J. T. (2007). Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacology & Therapeutics, 115(2), 246–270. DOI: 10.1016/j.pharmthera.2007.04.004
    SonD. J. LeeJ. W. LeeY. H. SongH. S. LeeC. K. HongJ. T. 2007 Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds Pharmacology & Therapeutics 115 2 246 270 10.1016/j.pharmthera.2007.04.004 17555825
    Open DOIBack to article
  41. Şirin, Y., Çakır, H. E., Can, Z., Yıldız, O., Kolaylı, S. (2016). The investigation of usage of sds-page electrophoresis in identification of honey bee venom. Uludag Bee Journal, 16(2), 49–56. (in Turkish).
    Search in Google ScholarBack to article
  42. Uzuner, S. Ç., Birinci, E., Tetikoğlu, S., Birinci, C., & Kolaylı, S. (2021). Distinct Epigenetic Reprogramming, Mitochondrial Patterns, Cellular Morphology and Cytotoxicity after Bee Venom Treatment. Recent Patents on Anti-cancer Drug Discovery. 16(3), 377–392. DOI: 10.2174/1574892816666210422125058
    UzunerS. Ç. BirinciE. TetikoğluS. BirinciC. KolaylıS. 2021 Distinct Epigenetic Reprogramming, Mitochondrial Patterns, Cellular Morphology and Cytotoxicity after Bee Venom Treatment Recent Patents on Anti-cancer Drug Discovery 16 3 377 392 10.2174/1574892816666210422125058 33888051
    Open DOIBack to article
  43. Varanda, E. A., & Tavares, D. C. (1998). Radioprotection: Mechanisms and Radioprotective Agents Including Honeybee Venom. Journal of Venomous Animals and Toxins including Tropical Diseases, 4(1), 5–21. DOI: 10.1590/S0104-79301998000100002
    VarandaE. A. TavaresD. C. 1998 Radioprotection: Mechanisms and Radioprotective Agents Including Honeybee Venom Journal of Venomous Animals and Toxins including Tropical Diseases 4 1 5 21 10.1590/S0104-79301998000100002
    Open DOIBack to article
  44. Zhou, J., Zhao, J., Zhang, S., Shen, J., Qi, Y., Xue, X., Li, Y. (2010). Quantification of melittin and apamin in bee venom lyophilized powder from Apis mellifera by liquid chromatography - diode array detector - tandem mass spectrometry. Analytical Biochemistry, 404(2), 171–178. DOI: 10.1016/j.ab.2010.05.014
    ZhouJ. ZhaoJ. ZhangS. ShenJ. QiY. XueX. LiY. 2010 Quantification of melittin and apamin in bee venom lyophilized powder from Apis mellifera by liquid chromatography - diode array detector - tandem mass spectrometry Analytical Biochemistry 404 2 171 178 10.1016/j.ab.2010.05.014 20580685
    Open DOIBack to article
DOI: https://doi.org/10.2478/jas-2022-0001 | Journal eISSN: 2299-4831 | Journal ISSN: 1643-4439
Journal RSS Feed
Language: English
Page range: 5 - 14
Submitted on: Feb 18, 2021
Accepted on: Dec 2, 2021
Published on: Jun 22, 2022
Published by: Research Institute of Horticulture
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
apamin,
harvesting method,
honeybee venom,
melittin,
Phospholipase A2,
season
Related subjects:
Life sciences,
Zoology,
Life sciences, other

© 2022 Meral Kekeçoğlu, Tuğçe Çaprazlı, Aslı E. Tanuğur Samancı, Taylan Samancı, Elif Yorulmaz Önder, published by Research Institute of Horticulture
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 66 (2022): Issue 1 (June 2022)
Next article