Abstract
The objective of this review was to discuss some of the criteria which influence the selection of microorganisms with probiotic properties based on their mode of action. The most common bacteria that belong to the “group” probiotics are the Lactobacillus and Bifidobacterium species/strains. Probiotics have benefits and effects by their mechanism of action in different axial locations such as: producing substances, influencing immune function and response, modification as well as maintenance of a healthy population of microorganisms in the intestinal environment. Probiotics have demonstrated significant potential as therapeutic options for a variety of diseases Potential peripheral pathways that link probiotic ingestion in the brain function are focused on the role of the vagal afferent nerve signalling and changes in the cerebral levels of neuromodulators. The application of probiotic microorganisms represents a way to effectively influence the composition of the intestinal microbiome and the immune system of the host, as well as they can be considered as a suitable alternative to influence a healthy quality of life.