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Smoking May Impact IL-33/ST2 Signaling for Better Cognitive Functioning in Schizophrenia Cover

Smoking May Impact IL-33/ST2 Signaling for Better Cognitive Functioning in Schizophrenia

Open Access
|Jun 2026

Figures & Tables

Figure 1.

Hypothesis-based model of potential smoking effects on cognition via IL-33/ST2 signaling. Proposed new cascade: with increasing cigarette consumption, there may be a decrease in serum levels of soluble suppressor of tumorigenicity (sST2) and, consequently, an increase in the level of free IL-33, which may affect the preservation of cognitive potential.
DOI: https://doi.org/10.2478/eabr-2026-0006 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
Language: English
Page range: 3 - 6
Submitted on: Dec 28, 2025
Accepted on: Feb 1, 2026
Published on: Jun 1, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Slavica Minic Janicijevic, Ivan P. Jovanovic, Zvezdana Stojanovic, Katarina Vesic, Milica M. Borovcanin, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.