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A Comparative Analysis of the Infrapatellar Fat Pad and Subcutaneous Adipose Tissue as Providers of Mesenchymal Stem Cells with Chondrogenic Potential: Quantitative Assessment through Immunohistochemical Methods Cover

A Comparative Analysis of the Infrapatellar Fat Pad and Subcutaneous Adipose Tissue as Providers of Mesenchymal Stem Cells with Chondrogenic Potential: Quantitative Assessment through Immunohistochemical Methods

EABR. Experimental and Applied Biomedical Research
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By: Maslennikov Serhii,  Chucha Oleh,  Valeriy Tumanskiy and  Maksym Golovakha  
Open Access
|Nov 2025

Figures & Tables

Figure 1.

Comprasion of Marker-Positive Cells in the infrapatellar fat pad (IPFP) and abdominal subcutaneous adipose tissue (SCAT)
Comprasion of Marker-Positive Cells in the infrapatellar fat pad (IPFP) and abdominal subcutaneous adipose tissue (SCAT)

Figure 2.

Immunohistochemical staining of biopsy samples from infrapatellar fat pad showing expression of CD44, CD166, and SOX9 markers (brown staining). Arrows
Immunohistochemical staining of biopsy samples from infrapatellar fat pad showing expression of CD44, CD166, and SOX9 markers (brown staining). Arrows

The relative number of cells expressing CD44+, CD166+, SOX9+ in the biopsy material of infrapatellar fat pad (IPFP) and abdominal subcutaneous adipose tissue (SCAT)

GROUPMARKERME (%)Q1 (%)Q3 (%)IQR (%)CV (%)
SCATCD166+1.100.801.500.7063.64
CD44+1.401.002.001.0071.43
Sox9+0.900.601.200.6066.67
IPFPCD166+10.348.2212.784.5644.10
CD44+13.288.5715.116.5449.25
Sox9+7.306.718.021.3117.95
DOI: https://doi.org/10.2478/eabr-2025-0013 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
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Language: English
Submitted on: May 7, 2025
Accepted on: May 7, 2025
Published on: Nov 5, 2025
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
Articular cartilage,
infrapatellar fat pad,
mesenchymal stem cells,
chondroprogenitors,
cartilage regeneration
Related subjects:
Medicine,
Clinical medicine,
Clinical medicine, other

© 2025 Maslennikov Serhii, Chucha Oleh, Valeriy Tumanskiy, Maksym Golovakha, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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