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Multimodal Imaging with MRI and [18F] FDG PET/CT in the Diagnosis and Assessment of Highly Aggressive NUT Carcinoma: A Case Study Cover

Multimodal Imaging with MRI and [18F] FDG PET/CT in the Diagnosis and Assessment of Highly Aggressive NUT Carcinoma: A Case Study

Biuletyn Głównej Biblioteki Lekarskiej
Volume 59 (2026): Issue 386 (June 2026)
By: ,   and    
Open Access
|Jun 2026
Figures & tables

Figures & Tables

Fig. 1.

MRI, T2-weighted, coronal plane, demonstrates a mass filling the left nasal cavity, sphenoid sinus, and ethmoid air cells. The tumor remodels the left maxillary sinus and extends intracranially.

Fig. 2.

Axial contrast-enhanced T1-weighted MRI demonstrates an enhancing mass extending into the anterior cranial fossa.

Fig. 3.

SWI MRI, axial plane shows a heterogeneous mass with intratumoral low-signal foci, consistent with hemosiderin deposition.

Fig. 4

Contrast-enhanced T1-weighted MRI, axial plane shows a heterogeneous mass in the left orbit. The mass displaces orbital contents, causing proptosis of the left eye.

Fig. 5

[18F] FDG PET/CT—shows increased tracer uptake in the primary lesion in the paranasal sinuses. This includes the left maxillary and sphenoid sinuses, extending to nearby bones and the left orbit.

Fig. 6

[18F] FDG PET/CT shows increased radiotracer uptake in the lungs (A), cervical lymph nodes (B), and mediastinal lymph nodes (C), all consistent with metastatic lesions.

Fig. 7

[18F] FDG PET/CT, Maximum Intensity Projection (MIP) image, shows a hypermetabolic mass extending into the anterior cranial fossa. Metastatic involvement is visible in the lymph nodes and lungs. Physiologic FDG uptake appears in the brain, salivary glands, and urinary tract.
DOI: https://doi.org/10.2478/bgbl-2026-0009 | Journal eISSN: 2956-6851 | Journal ISSN: 0373-174X
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Language: English
Page range: 145 - 155
Submitted on: May 12, 2026
Accepted on: May 25, 2026
Published on: Jun 28, 2026
Published by: The Medical Library named after S. Konopka in Warsaw
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
NUT carcinoma,
sinonasal carcinoma,
NUT protein,
NUTM1 rearrangements,
[18F] FDG PET/CT,
MRI
Related subjects:
Medicine,
Biomedical engineering

© 2026 Aleksandra Wiktoria Nowakowska, Michał Jędrzejewski, Jakub Kamiński, published by The Medical Library named after S. Konopka in Warsaw
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 59 (2026): Issue 386 (June 2026)
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