Neurosteroids in Cognitive Disorder - From Well-Known Pharmacological Aspects to a Source of Controversy

Mădălina-Georgiana Bătrînu; Amelia Tero-Vescan

doi:10.2478/amtsb-2020-0007

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Neurosteroids in Cognitive Disorder - From Well-Known Pharmacological Aspects to a Source of Controversy

Acta Medica Transilvanica

Volume 25 (2020): Issue 1 (March 2020)

By: Mădălina-Georgiana Bătrînu and Amelia Tero-Vescan

Open Access

|Aug 2020

Abstract

The nervous system is not just a target organ for synthetic steroids. It is also controlled in a certain manner by steroids synthesized de novo in the brain, at the level of both neurones and glial cells. The impressive recent number of literature studies, clearly demonstrates the presence of enzymes necessary for syntheses of central neurosteroids and also the mechanism by which they act. Neurosteroids play a considerable part as an endogenous modulator of brain function and behaviour processes, and the decrease of their concentration can be associated with the pathophysiology of different neurological diseases accompanied by cognitive disorders such as depression, anxiety, schizophrenia, Alzheimer disease.

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Articles in this issue

DOI: https://doi.org/10.2478/amtsb-2020-0007 | Journal eISSN: 2285-7079 | Journal ISSN: 2285-7079

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Language: English

Page range: 23 - 27

Submitted on: Jan 25, 2019

Accepted on: Feb 24, 2020

Published on: Aug 3, 2020

Published by: Lucian Blaga University of Sibiu

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

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© 2020 Mădălina-Georgiana Bătrînu, Amelia Tero-Vescan, published by Lucian Blaga University of Sibiu
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 25 (2020): Issue 1 (March 2020)