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Effect of Reproductive System Dysbiosis on the Course of Pregnancy Cover

Effect of Reproductive System Dysbiosis on the Course of Pregnancy

Open Access
|Jul 2024

Abstract

Genetic, endocrine and immunological disorders, anatomical defects in the reproductive tract, certain chronic diseases, toxic substances, or advanced age of the mother are most cited among the main causes of pregnancy loss at various stages. However, the cause of miscarriage or preterm labor in some cases remains unclear. Determination of the etiology about these clinical conditions may reduce the rate of reproductive failure. Similarly, the etiology of other obstetric disorders, such as preeclampsia or postpartum hemorrhage, has not been fully explained. One of the postulated and still under-researched causes of these disorders may be dysbiosis within the reproductive tract. A disturbed microbial balance is not always associated with the presence of an acute infection with clear clinical symptoms. Dysbiosis in conjunction with other pathophysiological factors may increase the risk of the mentioned clinical conditions. The aim of this paper is to show the information indicating the existence of a correlation between dysbiosis and an increase in the risk of obstetric disorders. Further analysis is also required to clarify the mechanism of the effect of dysbiosis on the disruption of metabolic and biochemical processes within the reproductive system during pregnancy.

DOI: https://doi.org/10.2478/am-2024-0008 | Journal eISSN: 2545-3149 | Journal ISSN: 0079-4252
Language: English, Polish
Page range: 93 - 99
Submitted on: Apr 1, 2024
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Accepted on: Jun 1, 2024
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Published on: Jul 3, 2024
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Karolina Piekarz, Barbara Macura, Aneta Kiecka, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.