Figure 1.
Synthesis and transformation of sulfane sulfur in biological systems
Abbreviations: S - sulfane sulfur atom (marked in red); (1) - S-sulfuration reaction; (2) - S-nitrosylation reaction; CBS - cystathionine β-synthase; CTH - cystathionine γ-lyase; MPST - 3-mercaptopyruvate sulfurtransferase; CDO - cysteine dioxygenase; RNS - reactive nitrogen species; ROS - reactive oxygen species
Table 1.
The list of human and animal tissues in which the level of sulfane sulfur was determined by the method of Wood. The given tissue and the reference referring to it are marked with the same number of asterisks
| Tissues | References |
|---|---|
| Human Liver, Brain | [44] |
| Rat Liver*, Heart and Kidney** | *[45], *[46], **[47] |
| Guinea pig Liver | [45] |
| Mouse Liver*,****, Kidney**,****, Heart****, Spleen****, Brain stem and cortex*** | *[48], **[49], ***[50], ****[51] |
| Rana temporaria Liver, Kidney, Gonads, Brain, Heart | [52] |
| Rana ridibunda Liver, Kidney, Brain, Heart, Testes, Skeletal muscles | [53], [54], [55] |
Figure 2.
The level of sulfane sulfur in human and animal tissues. Data from published experimental works cited in Table 1 were used in Figure 2. The bars correspond to the mean value ± SD (
standard deviation) of sulfane sulfur level expressed in nmoles of SCN− per mg of protein, from three or more determinations in at least three repetitions
Table 2.
Human and animal cells in which the level of sulfane sulfur was determined by the method of Wood
Figure 3.
The level of sulfane sulfur in human and animal cell cultures. Data from published experimental works cited in Table 2 were used in Figure 3. The bars correspond to the mean value ± SD (
standard deviation) of sulfane sulfur level in a particular cell culture, expressed in nmoles of SCN− per mg of protein, from at least three independent experiments, with three or more determinations in each
Figure 4.
The level of sulfane sulfur in Rana ridibunda tissues in the fall and spring seasons. Data from published experimental works [53, 54] were used in Figure 4. The bars correspond to the mean value ± SD (
standard deviation) of sulfane sulfur level expressed in nmoles of SCN− per mg of protein, from three or more determinations in at least three repetitions
Figure 5.
The level of sulfane sulfur in selected tissues of male and female mice. Data from published experimental work [51] were used in Figure 5. The bars correspond to the mean value ± SD (
standard deviation) of sulfane sulfur level expressed in nmoles of SCN− per mg of protein, from three or more determinations in at least three repetitions
Table 3.
The level of sulfane sulfur in various frog tissues exposed to heavy metal ions in water — based on results published in [55]
| SULFANE SULFUR % of control | |||
|---|---|---|---|
| Pb2+ | Cd2+ | Hg2+ | |
| Brain | 151.1 | 137.3 | 117.3 |
| Liver | 91.5 | 86.8 | 94.7 |
| Kidney | 133.2 | 109.5 | 91.7 |
| Heart | Not changed | Not changed | Not changed |
| Skeletal muscle | Not changed | Not changed | 120.3 |
| Testes | Not changed | 88.5 | 114.6 |