Development of carboxymethyl tamarind gum-based composite hydrogel films for wound dressing applications

Figures & Tables

Swelling profile of hydrogel films in Tris HCl buffer pH 7.4 (a) and 0.1 N HCl (b).

Batch	Drug loading (mg/g)	Q_5h (%)^a	Zero order	First order	Higuchi	Korsmeyer–Peppas		Order of release
Batch	Drug loading (mg/g)	Q_5h (%)^a	(r²)	(r²)	(r²)	(r²)	n	Order of release
HM1	34.58 ± 2.61	53.34 ± 2.58	0.881	0.733	0.967	0.968	0.511	Non-Fickian
HM2	37.45 ± 1.27	73.52 ± 3.09	0.795	0.640	0.914	0.939	0.552	Non-Fickian
HM3	34.58 ± 1.94	67.00 ± 2.77	0.798	0.637	0.916	0.931	0.567	Non-Fickian
HM4	30.45 ± 4.13	60.02 ± 1.62	0.799	0.643	0.916	0.936	0.588	Non-Fickian
HM5	36.66 ± 2.77	70.74 ± 2.71	0.740	0.582	0.871	0.897	0.535	Non-Fickian
HM6	43.86 ± 3.65	78.90 ± 3.73	0.792	0.623	0.908	0.908	0.523	Non-Fickian
HM7	39.99 ± 3.99	88.60 ± 3.27	0.809	0.627	0.917	0.892	0.514	Non-Fickian

Batch	Weight loss (%)	Thickness (μm)	TCC (mEq/100 g)	Contact angle (°)
HM1	30.28 ± 7.93	575.00 ± 7.26	350.33 ± 6.5	63.29 ± 0.47
HM2	29.89 ± 5.44	593.86 ± 4.79	370.67 ± 4.4	60.31 ± 0.49
HM3	32.33 ± 9.74	590.00 ± 4.41	407.00 ± 3.2	65.92 ± 0.38
HM4	34.17 ± 11.84	578.33 ± 6.01	427.35 ± 6.6	69.91 ± 0.39
HM5	33.03 ± 6.13	587.44 ± 7.43	390.33 ± 3.8	66.64 ± 0.22
HM6	35.15 ± 5.35	584.33 ± 6.89	331.67 ± 6.2	69.85 ± 0.55
HM7	37.21 ± 6.60	572.22 ± 3.47	304.33 ± 5.4	74.29 ± 0.18

Batch	HM1	HM2	HM3	HM4	HM5	HM6	HM7
CMTG:FSM ratio (2 % w/v)	1:0	9:1	9:1	9:1	8:2	7:3	1:1
Citric acid (% w/v)	0.6	0.5	0.6	0.7	0.6	0.6	0.6

Batch	WVTR (g/m²)	Microbial permeability	Protein adsorption (mg/cm²)	Hemolysis (%)
HM1	987.96	−ve	0.044	4.561
HM2	941.13	−ve	0.034	2.474
HM3	905.00	−ve	0.040	3.464
HM4	791.40	−ve	0.047	4.013
HM5	887.36	−ve	0.035	3.813
HM6	843.36	−ve	0.032	3.318
HM7	820.18	−ve	0.029	2.212