Figure 1.
Figure 2.
The activity of tested lyophilizates and selected secondary metabolites on the Enterococcus faecalis strains expressed as MIC and MBC in mg mL−1_
| E. faecalis strain | Clinical 1 | Clinical 2 | Clinical 3 | CCM 4224 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GTWE | MIC | 2.5 | 1.25 | 1.25 | 2.5 | 2.5 | 2.5 | 2.5 | 1.25 | 2.5 | 2.5 | 2.5 | 2.5 |
| ~ | 1.25 | 2.5 | 2.5 | 2.5 | |||||||||
| MBC | 5 | 5 | 5 | 5 | 10 | 10 | 5 | 10 | 5 | 5 | 5 | 5 | |
| ~ | 5 | 10 | 5 | 5 | |||||||||
| PLWE | MIC | 2.5 | 2.5 | 2.5 | |||||||||
| ~ | ND | ND | ND | 2.5 | |||||||||
| MBC | >5 | >5 | >5 | ||||||||||
| ~ | >5 | ||||||||||||
| GT + PLWE | MIC | 5 | 10 | 10 | 2.5 | 10 | 10 | 5 | 10 | 10 | 5 | 10 | 10 |
| ~ | 10 | 10 | 10 | 10 | |||||||||
| MBC | 5 | >10 | >10 | 10 | >10 | >10 | 10 | >10 | >10 | 5 | 10 | 10 | |
| ~ | >10 | >10 | >10 | 10 | |||||||||
| RA | MIC | 5 | >5 | >5 | 5 | 5 | 5 | 5 | >5 | >5 | 2.5 | 5 | >5 |
| ~ | >5 | 5 | >5 | 5 | |||||||||
| MBC | >5 | >5 | >5 | >5 | 5 | 5 | >5 | >5 | >5 | >5 | 5 | >5 | |
| ~ | >5 | 5 | >5 | >5 | |||||||||
| EC | MIC | ||||||||||||
| >1 mg mL−1 | >1 mg mL−1 | >1 mg mL−1 | >1 mg mL−1 | ||||||||||
| MBC | |||||||||||||
| ~ | >1 mg mL−1 | >1 mg mL−1 | >1 mg mL−1 | >1 mg mL−1 | |||||||||
| ECGC | MIC | 0.25 | 0.5 | 0.25 | 0.125 | 0.5 | 0.5 | 0.25 | 0.5 | 0.5 | 0.25 | 0.25 | 0.5 |
| ~ | 0.25 | 0.5 | 0.5 | 0.25 | |||||||||
| MBC | 1 | >0.5 | >0.5 | 1 | >0.5 | >0.5 | 1 | >0.5 | >0.5 | 1 | >0.5 | >0.5 | |
| ~ | 1 | 1 | 1 | 1 | |||||||||
| CA | MIC | >1 | 2.5 | 2.5 | >1 | 2.5 | 2.5 | >1 | 1.25 | 2.5 | >1 | 1.25 | 2.5 |
| ~ | 2.5 | 2.5 | 2.5 | 2.5 | |||||||||
| MBC | >1 | 2.5 | 2.5 | >1 | 2.5 | 2.5 | >1 | 1.25 | 2.5 | >1 | 1.25 | 2.5 | |
| ~ | 2.5 | 2.5 | 2.5 | 2.5 | |||||||||