Figure 1.

Joint and muscle forces and moments
| Lead author | Intervention | Outcome measure | Baseline | Final | Change | p-value |
|---|---|---|---|---|---|---|
| Kernozek [50] | Squatting with 3D motion capture analysis VF (post-training) | PFJ force (BW) | 4.64 ± 1.05 | 3.97 ± 0.81 | −0.67 BW | <0.001a |
| Knee extension moment (Nm/BW) | 0.11 ± 0.02 | 0.10 ± 0.02 | −0.01 Nm/BW | 0.01a | ||
| Hip extension moment (Nm/BW) | 0.06 ± 0.04 | 0.04 ± 0.03 | −0.02 Nm/BW | 0.001a | ||
| Quadriceps forces (BW) | 4.67 ± 0.98 | 4.06 ± 0.87 | −0.61 BW | <0.001 |
j_advrehab-2026-0003_tab_007
| Search term | Alternate terms included | Search details |
|---|---|---|
| #1: Knee pain | Knee ache, PFP | (((‘knee’[MeSH Terms] OR ‘knee’[All Fields] OR ‘knee joint’[MeSH Terms] OR (‘knee’[All Fields] AND ‘joint’[All Fields]) OR ‘knee joint’[All Fields]) AND (‘pain’[MeSH Terms] OR ‘pain’[All Fields])) OR ((‘knee’[MeSH Terms] OR ‘knee’[All Fields] OR ‘knee joint’[MeSH Terms] OR (‘knee’[All Fields] AND ‘joint’[All Fields]) OR ‘knee joint’[All Fields]) AND (‘ache protein human’[Supplementary Concept] OR ‘ache protein human’[All Fields] OR ‘ache’[All Fields] OR ‘pain’[MeSH Terms] OR ‘pain’[All Fields])) OR (‘patellofemoral pain syndrome’[MeSH Terms] OR (‘patellofemoral’[All Fields] AND ‘pain’[All Fields] AND ‘syndrome’[All Fields]) OR ‘patellofemoral pain syndrome’[All Fields] OR (‘patellofemoral’[All Fields] AND ‘pain’[All Fields]) OR ‘patellofemoral pain’[All Fields])) |
| #2: VF | Feedback, biofeedback, mirror therapy, virtual reality, gamification, CAREN, Computer assisted rehabilitation environment, external focus | (‘feedback, sensory’[MeSH Terms] OR (‘feedback’[All Fields] AND ‘sensory’[All Fields]) OR ‘sensory feedback’[All Fields] OR (‘visual’[All Fields] AND ‘feedback’[All Fields]) OR ‘visual feedback’[All Fields] OR (‘feedback’[MeSH Terms] OR ‘feedback’[All Fields] OR ‘feedbacks’[All Fields] OR ‘feedback s’[All Fields]) OR (‘biofeedback, psychology’[MeSH Terms] OR (‘biofeedback’[All Fields] AND ‘psychology’[All Fields]) OR ‘psychology biofeedback’[All Fields] OR ‘biofeedback’[All Fields]) OR (‘mirror movement therapy’[MeSH Terms] OR (‘mirror’[All Fields] AND ‘movement’[All Fields] AND ‘therapy’[All Fields]) OR ‘mirror movement therapy’[All Fields] OR (‘mirror’[All Fields] AND ‘therapy’[All Fields]) OR ‘mirror therapy’[All Fields]) OR (‘virtual reality’[MeSH Terms] OR (‘virtual’[All Fields] AND ‘reality’[All Fields]) OR ‘virtual reality’[All Fields]) OR (‘gamification’[MeSH Terms] OR ‘gamification’[All Fields]) OR ‘CAREN’[All Fields] OR ((‘computability’[All Fields] OR ‘computable’[All Fields] OR ‘computating’[All Fields] OR ‘computation’[All Fields] OR ‘computational’[All Fields] OR ‘computations’[All Fields] OR ‘compute’[All Fields] OR ‘computed’[All Fields] OR ‘computer s’[All Fields] OR ‘computers’[MeSH Terms] OR ‘computers’[All Fields] OR ‘computer’[All Fields] OR ‘computes’[All Fields] OR ‘computing’[All Fields] OR ‘computional’[All Fields]) AND (‘assistances’[All Fields] OR ‘assistant s’[All Fields] OR ‘assistants’[All Fields] OR ‘assisted’[All Fields] OR ‘assisting’[All Fields] OR ‘assistive’[All Fields] OR ‘dental assistants’[MeSH Terms] OR (‘dental’[All Fields] AND ‘assistants’[All Fields]) OR ‘dental assistants’[All Fields] OR ‘assistant’[All Fields] OR ‘helping behavior’[MeSH Terms] OR (‘helping’[All Fields] AND ‘behavior’[All Fields]) OR ‘helping behavior’[All Fields] OR ‘assist’[All Fields] OR ‘assistance’[All Fields] OR ‘assists’[All Fields]) AND (‘rehabilitant’[All Fields] OR ‘rehabilitants’[All Fields] OR ‘rehabilitate’[All Fields] OR ‘rehabilitated’[All Fields] OR ‘rehabilitates’[All Fields] OR ‘rehabilitating’[All Fields] OR ‘rehabilitation’[MeSH Terms] OR ‘rehabilitation’[All Fields] OR ‘rehabilitations’[All Fields] OR ‘rehabilitative’[All Fields] OR ‘rehabilitation’[MeSH Subheading] OR ‘rehabilitation s’[All Fields] OR ‘rehabilitational’[All Fields] OR ‘rehabilitator’[All Fields] OR ‘rehabilitators’[All Fields]) AND (‘environ’[All Fields] OR ‘environment’[MeSH Terms] OR ‘environment’[All Fields] OR ‘environments’[All Fields] OR ‘environment s’[All Fields] OR ‘environs’[All Fields])) OR ((‘external’[All Fields] OR ‘externally’[All Fields] OR ‘externals’[All Fields]) AND (‘wood des focus’[Journal] OR ‘focus’[Journal] OR ‘focus ohio dent’[Journal] OR ‘focus madison’[Journal] OR ‘focus am psychiatr publ’[Journal] OR ‘focus’[All Fields]))) |
| #3: CKC | Squat, biomechana, functional movement | (((‘close’[All Fields] OR ‘closed’[All Fields] OR ‘closely’[All Fields] OR ‘closeness’[All Fields] OR ‘closes’[All Fields] OR ‘closing’[All Fields] OR ‘closings’[All Fields]) AND (‘kinetical’[All Fields] OR ‘kinetically’[All Fields] OR ‘kinetics’[MeSH Terms] OR ‘kinetics’[All Fields] OR ‘kinetic’[All Fields]) AND (‘chain’[All Fields] OR ‘chain s’[All Fields] OR ‘chains’[All Fields])) OR ‘squat*’[All Fields] OR ‘biomechan*’[All Fields] OR ((‘functional’[All Fields] OR ‘functional s’[All Fields] OR ‘functionalities’[All Fields] OR ‘functionality’[All Fields] OR ‘functionalization’[All Fields] OR ‘functionalizations’[All Fields] OR ‘functionalize’[All Fields] OR ‘functionalized’[All Fields] OR ‘functionalizes’[All Fields] OR ‘functionalizing’[All Fields] OR ‘functionally’[All Fields] OR ‘functionals’[All Fields] OR ‘functioned’[All Fields] OR ‘functioning’[All Fields] OR ‘functionings’[All Fields] OR ‘functions’[All Fields] OR ‘physiology’[MeSH Subheading] OR ‘physiology’[All Fields] OR ‘function’[All Fields] OR ‘physiology’[MeSH Terms]) AND (‘movement’[MeSH Terms] OR ‘movement’[All Fields] OR ‘movements’[All Fields] OR ‘movement s’[All Fields]))) |
| #4: #1 AND #2 AND #3 | ||
| #5: #4 with filters of randomized controlled trial, clinical trial, english language, and publication date of 2009–2024 |
Muscle activity (EMG)
| Lead author | Intervention | Muscle | Baseline | Final | Change |
|---|---|---|---|---|---|
| Hwangbo [48] | Visual EMG feedbacka | VM | 46.94 ± 5.36 | 50.51 ± 4.78 | +3.57 ± 2.28 |
| No feedback | VM | 43.40 ± 4.98 | 45.85 ± 6.95 | +2.45 ± 3.26 | |
| Visual EMG feedbacka | VL | 60.84 ± 6.54 | 61.75 ± 7.72 | +0.91 ± 3.40 | |
| No feedbacka | VL | 58.37 ± 5.72 | 62.43 ± 7.18 | +4.06 ± 3.66 |
Summary of study interventions, outcomes and key findings
| Lead author | Intervention | Comparator | Outcomes | Total follow-up period | Key findings | Risk of bias |
|---|---|---|---|---|---|---|
| Hwangbo [48] | Squat exercises with EMG VF | Squat exercises without VF | Muscle Activity (EMG): VM, VL | 6 weeks |
| High |
| Rabelo [49] | MC&S with mirror VF | Strengthening only | Pain: NPRS | 4 weeks (kinematics) 6 months (NPRS, AKPS) |
| Some concerns |
| Kernozek [50] | Post-training squatting with 3D motion capture analysis VF | Pre-training squatting without VF | Joint Forces/Moments: PFJ force, knee & hip ext. moment, quad force Joint Angles: hip, knee, ankle | Immediate |
| Moderate |
j_advrehab-2026-0003_tab_008
| Lead author | Risk of bias tool | Study design | Key domains | Overall risk of bias |
|---|---|---|---|---|
| Rabelo [49] | RoB 2 | RCT |
| Some concerns |
| Hwangbo [48] | RoB 2 | RCT |
| High |
| Kernozek [50] | ROBINS-I | NRSI |
| Moderate |
Study and participant characteristics
| Hwangbo [48] | Rabelo [49] | Kernozek [50] | |
|---|---|---|---|
| Population | N: 20 | N: 34 | N: 20 |
| Age: 22–23 years | Age: 18–30 years | Age: 18–25 years | |
| Sex: not reported | Sex: All female | Sex: 17 females, 3 males | |
| Inclusion criteria | Increased quadriceps (Q) angles | Clinical diagnosis of PFP; symptoms ≥3 months; pain with squatting/stairs | Clinical criteria for PFP; NPRS ≥3 during activity |
| Study design | RCT | RCT | NRSI |
| Experimental group | Squat exercises with EMG VF | Motor control and strengthening with mirror VF | Squatting with 3D motion capture analysis VF (post-training) |
| Comparator group | Squat exercises with no VF | Strengthening only | Squatting with no VF (pre-training) |
| Outcomes | VL and VM EMG | Function, pain intensity, strength, trunk and lower limb kinematics | Joint and muscle forces, joint angles |
Pain and functional outcomes
| Lead author | Intervention | Outcome measure | Baseline | Final | Between-group difference (95% CI) | p-value |
|---|---|---|---|---|---|---|
| Rabelo [49] | MC&S | NPRS | 6.1 ± 1.4 | 1.3 ± 1.8 | −0.3 (−1.7 to 1.0) | >0.05 |
| Strengthening only | NPRS | 6.6 ± 1.0 | 2.2 ± 1.6 | |||
| MC&S | AKPS (0–100) | 67.1 ± 7.6 | 89.0 ± 8.2 | −8.5 (−16.8 to −0.3) | 0.04a | |
| Strengthening only | AKPS (0–100) | 67.5 ± 11.3 | 84.8 ± 9.8 |
Joint angles (degrees)
| Lead author | Intervention | Joint angle | Baseline | Final | Change | p-value |
|---|---|---|---|---|---|---|
| Kernozek [50] | Squatting with 3D motion capture analysis VF (post-training) | Hip flexion | 91.99 ± 14.60 | 86.20 ± 15.05 | −5.79 | 0.001a |
| Knee flexion | 102.96 ± 16.55 | 97.26 ± 17.11 | −5.70 | 0.001a | ||
| Ankle dorsiflexion | 35.63 ± 6.95 | 34.77 ± 7.28 | −0.86 | 0.07 | ||
| Rabelo [49] | MC&S with mirror VF | Trunk ipsilateral lean | 5.0 ± 3.7 | 3.9 ± 2.3 | −1.1 | 0.02b |
| Strengthening only | Trunk ipsilateral lean | 4.4 ± 1.7 | 3.2 ± 1.6 | −1.2 |