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Cardiac Stem Cell Therapy, Resident Progenitor Cells and the role of Cellular Signalling; a Review Cover

Cardiac Stem Cell Therapy, Resident Progenitor Cells and the role of Cellular Signalling; a Review

Open Access
|Nov 2019

Figures & Tables

Summary of Distinct CPC populations_ List of CPCs discovered, species cell type identified in, cell lineages associated with cell type, cellular markers defining unique cell type, literature used to gather information

CPC POPULATIONSPECIESASSOCIATED CELL LINEAGESCELLULAR MARKERSREFERENCES
c-Kit+Human, mouse, rat, dog, pigEndothelialc-Kit+, CD34-, CD45-, Sca-1+, Abcg2+, CD105+, CD166+, GATA4+, NKX2-5+/-, MEF2c+[9] [47]
Sca-1+MouseEndothelial, Smooth muscleSca-1+, CD105+, CD34-, CD45-, FLK1-, c-Kit+/-, GATA4+, NKX2-5+/-, MEF2C+[9] [47]
Epicardium-deri- ved cellsHuman, mouseMesenchymal, fibroblast, smooth muscleCD34+, c-Kit+/-, CD44+, CD90+, CD105+, CD46+[9] [47]
Cardiosphere-de- rived cellsHuman, mouse, rat, dog, pigCardiomyocytes, endothelial, smooth muscleCD31+, CD34+, c-Kit(low), Sca1+, CD45+, CD105+, Abcg2+[9] [47]
Islet-1+Mouse, rat, humanSecond heart field, Cardiac neural crestIsl-1+, CD31-, Sca-1-, c-Kit+/-, GATA4+, NKX2-5+[9] [47]
Side Population CellsMouse, ratCardiomyocyte, fibroblast, endothelial, smooth muscleCD34+, CD45+, Abcg2+, Sca-1+, c-Kit+, NKX2-5-, GATA4-[9] [47]
Cardiac colony forming unit fibroblastsMouseMesenchymalPDGFR-a+, Sca-1+, CD31-, CD90+, c-Kit(low), CD45-, FLK1-, CD44+, CD29+, CD105+[9] [47]
Language: English
Page range: 112 - 118
Submitted on: Sep 12, 2019
Accepted on: Oct 21, 2019
Published on: Nov 8, 2019
Published by: Foundation for Cell Biology and Molecular Biology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2019 Greg Hutchings, Mariusz J. Nawrocki, Paul Mozdziak, Bartosz Kempisty, published by Foundation for Cell Biology and Molecular Biology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.