Table 1
Summary of Distinct CPC populations. List of CPCs discovered, species cell type identified in, cell lineages associated with cell type, cellular markers defining unique cell type, literature used to gather information
| CPC POPULATION | SPECIES | ASSOCIATED CELL LINEAGES | CELLULAR MARKERS | REFERENCES |
|---|---|---|---|---|
| c-Kit+ | Human, mouse, rat, dog, pig | Endothelial | c-Kit+, CD34-, CD45-, Sca-1+, Abcg2+, CD105+, CD166+, GATA4+, NKX2-5+/-, MEF2c+ | [9] [47] |
| Sca-1+ | Mouse | Endothelial, Smooth muscle | Sca-1+, CD105+, CD34-, CD45-, FLK1-, c-Kit+/-, GATA4+, NKX2-5+/-, MEF2C+ | [9] [47] |
| Epicardium-deri- ved cells | Human, mouse | Mesenchymal, fibroblast, smooth muscle | CD34+, c-Kit+/-, CD44+, CD90+, CD105+, CD46+ | [9] [47] |
| Cardiosphere-de- rived cells | Human, mouse, rat, dog, pig | Cardiomyocytes, endothelial, smooth muscle | CD31+, CD34+, c-Kit(low), Sca1+, CD45+, CD105+, Abcg2+ | [9] [47] |
| Islet-1+ | Mouse, rat, human | Second heart field, Cardiac neural crest | Isl-1+, CD31-, Sca-1-, c-Kit+/-, GATA4+, NKX2-5+ | [9] [47] |
| Side Population Cells | Mouse, rat | Cardiomyocyte, fibroblast, endothelial, smooth muscle | CD34+, CD45+, Abcg2+, Sca-1+, c-Kit+, NKX2-5-, GATA4- | [9] [47] |
| Cardiac colony forming unit fibroblasts | Mouse | Mesenchymal | PDGFR-a+, Sca-1+, CD31-, CD90+, c-Kit(low), CD45-, FLK1-, CD44+, CD29+, CD105+ | [9] [47] |