Cardiac Stem Cell Therapy, Resident Progenitor Cells and the role of Cellular Signalling; a Review

Hutchings, Greg; Nawrocki, Mariusz J.; Mozdziak, Paul; Kempisty, Bartosz

doi:10.2478/acb-2019-0015

References

World Health Organisation. Cardiovascular diseases (CVDs) 2017 https://www.who.int/news-room/fact-sheets/detail/cardiovascular-di-seases-(cvds) (accessed September 15, 2019).
Search in Google Scholar Back to article
Wilkins E, L. W, Wickramasinghe K, P B. European Cardiovascular Disease Statistics 2017 edition. Eur Hear Netw. 2017:8–15; 94, 118, 127, 149, 162, 174.
Search in Google Scholar Back to article
World Health Organisation. Obesity and overweight 2018https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight (accessed September 15, 2019).
Search in Google Scholar Back to article
WHO global report on trends in prevalence of tobacco smoking 2000-2025 , second edition ISBN 978-92-4-151417-0.
Search in Google Scholar Back to article
Amini H, Rezaie J, Vosoughi A, Rahbarghazi R, Nouri M. Cardiac progenitor cells application in cardiovascular disease. J Cardiovasc Thorac Res. 2017;9:127–32; DOI:10.15171/jcvtr.2017.22.
Open DOI Search in Google Scholar Back to article
Barile L, Cervio E, Lionetti V, Milano G, Ciullo A, Biemmi V, Bolis S, Altomare C, Matteucci M, Di Silvestre D, Brambilla F, Fertig TE, Torre T, Demertzis S, Mauri P, Moccetti T, Vassalli G. Cardioprotection by cardiac progenitor cell-secreted exosomes: Role of pregnancy-associated plasma protein-A. Cardiovasc Res. 2018;114:992–1005; DOI:10.1093/cvr/cvy055.
Open DOI Search in Google Scholar Back to article
Gartz M, Strande JL. Examining the paracrine effects of exosomes in cardiovascular disease and repair. J Am Heart Assoc. 2018;7:1–13; DOI:10.1161/JAHA.117.007954.
Open DOI Search in Google Scholar Back to article
Li Y, He L, Huang X, Bhaloo SI, Zhao H, Zhang S, Pu W, Tian X, Li Y, Liu Q, Yu W, Zhang L, Liu X, Liu K, Tang J, Zhang H, Cai D, Ralf AH, Xu Q, Lui KO, Zhou B. Genetic lineage tracing of nonmyocyte population by dual recombinases. Circulation. 2018;138:793–805; DOI:10.1161/CIRCULATIONAHA.118.034250.
Open DOI Search in Google Scholar Back to article
Le T, Chong J. Cardiac progenitor cells for heart repair. Cell Death Discov. 2016;2:1–4; DOI:10.1038/cddiscovery.2016.52.
Open DOI Search in Google Scholar Back to article
Bolli R, Chugh AR, D’Amario D, Loughran JH, Stoddard MF, Ikram S, Beache GM, Wagner SG, Leri A, Hosoda T, Sanada F, Elmore JB, Goichberg P, Cappetta D, Solankhi NK, Fahsah I, Rokosh DG, Slaughter MS, Kajstura J, Anversa P. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): Initial results of a randomised phase 1 trial. Lancet. 2011;378:1847–57; DOI:10.1016/S0140-6736(11)61590-0.
Open DOI Search in Google Scholar Back to article
Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LEJ, Berman D, Czer LSC, Marbán L, Mendizabal A, Johnston P V, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marbán E. NIH Public Access 2015;379:895– 904; DOI:10.1016/S0140-6736(12)60195-0.Intracoronary.
Open DOI Search in Google Scholar Back to article
Ellison GM, Vicinanza C, Smith AJ, Aquila I, Leone A, Waring CD, Henning BJ, Stirparo GG, Papait R, Scarfò M, Agosti V, Viglietto G, Condorelli G, Indolfi C, Ottolenghi S, Torella D, Nadal-Ginard B. Adult c-kitpos cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell. 2013;154:827–42; DOI:10.1016/j.cell.2013.07.039.
Open DOI Search in Google Scholar Back to article
Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, Jeong D, Sheng W, Bu L, Xu M, Huang GY, Hajjar RJ, Zhou B, Moon A, Cai CL. Resident c-kit + cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:1–10; DOI:10.1038/ncomms9701.
Open DOI Search in Google Scholar Back to article
Vagnozzi RJ, Sargent MA, Lin SCJ, Palpant NJ, Murry CE, Molkentin JD. Genetic lineage tracing of Sca-1+ cells reveals endothelial but not myogenic contribution to the murine heart. Circulation. 2018;138:2931–9; DOI:10.1161/CIRCULATIONAHA.118.035210.
Open DOI Search in Google Scholar Back to article
Gallet R, Marban E. Cardiosphere - derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction. Vol. 1. 2019.
Search in Google Scholar Back to article
Han C, Sun X, Liu L, Jiang H, Shen Y, Xu X, Li J, Zhang G, Huang J, Lin Z, Xiong N, Wang T. Exosomes and their therapeutic potentials of stem cells. Stem Cells Int. 2016;2016; DOI:10.1155/2016/7653489.
Open DOI Search in Google Scholar Back to article
Xu MY, Ye ZS, Song XT, Huang RC. Differences in the cargos and functions of exosomes derived from six cardiac cell types: A systematic review. Stem Cell Res Ther. 2019;10:1–11; DOI:10.1186/s13287-019-1297-7.
Open DOI Search in Google Scholar Back to article
Page C. Cellular Communication in Cardiac Regeneration Janita A . Maring. 2019.
Search in Google Scholar Back to article
Drowley L, McPheat J, Nordqvist A, Peel S, Karlsson U, Martinsson S, Müllers E, Dellsén A, Knight S, Barrett I, Sánchez J, Magnusson B, Greber B, Wang QD, Plowright AT. Discovery of Retinoic Acid Receptor Agonists as Proliferators of Cardiac Progenitor Cells Through a Phenotypic Screening Approach n.d. Stem Cells Translational Medicine. 2019. DOI:10.1002/sctm.19-0069.
Open DOI Search in Google Scholar Back to article
Stuckmann I, Evans S, Lassar AB. Erythropoietin and retinoic acid , secreted from the epicardium , are required for cardiac myocyte proliferation 2003;255:334–49; DOI:10.1016/S0012-1606(02)00078-7.
Open DOI Search in Google Scholar Back to article
Andrade D, Oliveira G, Menezes L, Nascimento AL, Stumbo AC, Thole A, Garcia-souza É, Carvalho L, Cortez E. Insulin-like growth factor-1 short-period therapy improves cardiomyopathy stimulating cardiac progenitor cells survival in obese mice. Nutr Metab Cardiovasc Dis. 2019; DOI:10.1016/j.numecd.2019.09.001.
Open DOI Search in Google Scholar Back to article
Perez-martinez C, Prado P De, Vicinanza C, Purushothaman S, Bs C, Galuppo V, Iaconetti C, Waring CD, Smith A, Torella M, Ramon CC, Gonzalo-orden JM, Agosti V, Indolfi C, Galiñanes M, Fernandez-vazquez F, Nadal-ginard B. Endogenous Cardiac Stem Cell Activation by Insulin-Like Growth Factor-1 / Hepatocyte Growth Factor Intracoronary Injection Fosters Survival and Regeneration of the Infarcted Pig Heart. JAC. 2011;58:977–86; DOI:10.1016/j.jacc.2011.05.013.
Open DOI Search in Google Scholar Back to article
Alam P, Haile B, Arif M, Pandey R, Rokvic M, Nieman M, Maliken BD, Paul A, Wang Y, Sadayappan S, Ahmed RPH, Kanisicak O. Inhibition of Senescence‐Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post–Myocardial Infarction . J Am Heart Assoc. 2019;8; DOI:10.1161/jaha.119.012089.
Open DOI Search in Google Scholar Back to article
Shin J, Choi S, Kim JH, Cho JH, Jin Y, Kim S, Min S, Kim SK, Choi D, Cho S. Tissue Tapes — Phenolic Hyaluronic Acid Hydrogel Patches for Off-the-Shelf Therapy 2019;1903863:1–15; DOI:10.1002/adfm.201903863.
Open DOI Search in Google Scholar Back to article
Mohamed TMA, Ang YS, Radzinsky E, Zhou P, Huang Y, Elfenbein A, Foley A, Magnitsky S, Srivastava D. Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. 2018;173:104-116.e12; DOI:10.1016/j.cell.2018.02.014.
Open DOI Search in Google Scholar Back to article
Jha S, Rollins MG, Fuchs G, Procter DJ, Hall EA, Cozzolino K, Sarnow P, Savas JN, Walsh D. HHS Public Access 2017;546:651–5; DOI:10.1038/nature22814.Trans-kingdom.
Open DOI Search in Google Scholar Back to article
Gao Z, Zhu X, Dou Y. The MIR-302/367 cluster: A comprehensive update on its evolution and functions. Open Biol. 2015;5; DOI:10.1098/rsob.150138.
Open DOI Search in Google Scholar Back to article
Liu W, Wen Y, Bi P, Lai X, Liu XS, Liu X, Kuang S. Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation. Dev. 2012;139:2857–65; DOI:10.1242/dev.079665.
Open DOI Search in Google Scholar Back to article
Tong W, Xiong F, Li Y, Zhang L. Hypoxia inhibits cardiomyocyte proliferation in fetal rat hearts via upregulating TIMP-4. Am J Physiol - Regul Integr Comp Physiol. 2013;304:613–20; DOI:10.1152/ajpregu.00515.2012.
Open DOI Search in Google Scholar Back to article
Paradis AN, Gay MS, Wilson CG, Zhang L. Newborn hypoxia/anoxia inhibits cardiomyocyte proliferation and decreases cardiomyocyte endowment in the developing heart: Role of endothelin-1. PLoS One. 2015;10:1–21; DOI:10.1371/journal.pone.0116600.
Open DOI Search in Google Scholar Back to article
Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA. Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature. 2015;523:226–30; DOI:10.1038/nature14582.
Open DOI Search in Google Scholar Back to article
Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA. Hypoxia induces heart regeneration in adult mice. Nature. 2017;541:222–7; DOI:10.1038/nature20173.
Open DOI Search in Google Scholar Back to article
Sun Y, Jiang C, Hong H, Liu J, Qiu L, Huang Y, Ye L. Effects of hypoxia on cardiomyocyte proliferation and association with stage of development. Biomed Pharmacother. 2019;118:109391; DOI:10.1016/j. biopha.2019.109391.
Open DOI Search in Google Scholar Back to article
Zhuang LEI, Xia W, Hou M. Co ‑ culturing with hypoxia pre-conditioned mesenchymal stem cells as a new strategy for the prevention of irradiation-induced fibroblast ‑ to ‑ myofibroblast transition 2019:1–12; DOI:10.3892/or.2019.7293.
Open DOI Search in Google Scholar Back to article
Patel B, Bansal SS, Ismahil MA, Hamid T, Rokosh G, Mack M, Prabhu SD. CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload. JACC Basic to Transl Sci. 2018;3:230–44; DOI:10.1016/j.jacbts.2017.12.006.
Open DOI Search in Google Scholar Back to article
Psarras S, Beis D, Nikouli S, Tsikitis M, Capetanaki Y. Three in a Box: Understanding Cardiomyocyte, Fibroblast, and Innate Immune Cell Interactions to Orchestrate Cardiac Repair Processes. Front Cardiovasc Med. 2019;6:1–23; DOI:10.3389/fcvm.2019.00032.
Open DOI Search in Google Scholar Back to article
Doppler SA, Carvalho C, Lahm H, Deutsch MA, Dreßen M, Puluca N, Lange R, Krane M. Cardiac fibroblasts: More than mechanical support. J Thorac Dis. 2017;9:S36–51; DOI:10.21037/jtd.2017.03.122.
Open DOI Search in Google Scholar Back to article
Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D. Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling. Dev Cell. 2009;16:233–44; DOI:10.1016/j. devcel.2008.12.007.
Open DOI Search in Google Scholar Back to article
Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 2010;142:375–86; DOI:10.1016/j.cell.2010.07.002.
Open DOI Search in Google Scholar Back to article
Inagawa K, Ieda M. Direct reprogramming of mouse fibroblasts into cardiac myocytes. J Cardiovasc Transl Res. 2013;6:37–45; DOI:10.1007/s12265-012-9412-5.
Open DOI Search in Google Scholar Back to article
Min YL, Jaichander P, Sanchez-Ortiz E, Bezprozvannaya S, Malladi VS, Cui M, Wang Z, Bassel-Duby R, Olson EN, Liu N. Identification of a multipotent Twist2-expressing cell population in the adult heart. Proc Natl Acad Sci US A. 2018;115:E8430–9; DOI:10.1073/pnas.1800526115.
Open DOI Search in Google Scholar Back to article
Xu J, Xiong YY, Li Q, Hu MJ, Huang PS, Xu JY, Tian XQ, Jin C, Liu JD, Qian L, Yang YJ. Optimization of Timing and Times for Administration of Atorvastatin-Pretreated Mesenchymal Stem Cells in a Preclinical Model of Acute Myocardial Infarction. Stem Cells Transl Med. 2019;8:1068-1083: DOI: 10.1002/sctm.19-0013
Open DOI Search in Google Scholar Back to article
Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabé-Heide F, Walsh S, Zupicich J, Alkass K, Buchholz BA, Druid H, Jovinge S, Frisén J. Evidence for cardiomyocyte renewal in humans. Science. 2009;324:98–102; DOI:10.1126/science.1164680.
Open DOI Search in Google Scholar Back to article
Zebrowski DC, Becker R, Engel FB. Towards regenerating the mammalian heart: Challenges in evaluating experimentally induced adult mammalian cardiomyocyte proliferation. Am J Physiol - Hear Circ Physiol. 2016;310:H1045–54; DOI:10.1152/ajpheart.00697.2015.
Open DOI Search in Google Scholar Back to article
Ayala‐Mar S, Donoso‐Quezada J, Gallo‐Villanueva RC, Pérez‐González VH, González‐Valdez J. Recent advances and challenges in the recovery and purification of cellular exosomes. Electrophoresis. 2019:1–14; DOI:10.1002/elps.201800526.
Open DOI Search in Google Scholar Back to article
Trac D, Hoffman JR, Bheri S, Maxwell JT, Platt MO, Davis ME. Predicting Functional Responses of Progenitor Cell Exosome Potential with Computational Modeling. Stem Cells Transl Med. 2019; DOI:10.1002/ sctm.19-0059.
Open DOI Search in Google Scholar Back to article
Li P, Kaslan M, Lee SH, Yao J, Gao Z. Progress in exosome isolation techniques. Theranostics. 2017;7:789–804; DOI:10.7150/thno.18133.
Open DOI Search in Google Scholar Back to article
Park JH, Lee NK, Lim HJ, Mazumder S, Rethineswaran VK, Kim YJ, Jang WB, Ji ST, Kang S, Kim DY, Van LTH, Giang LTT, Kim DH, Ha JS, Yun J, Kim H, Han J, Mishchenko NP, Fedoreyev SA, Vasileva EA, Kwon SM, Baek SH. Therapeutic cell protective role of histochrome under oxidative stress in human cardiac progenitor cells. Mar Drugs. 2019;17; DOI:10.3390/md17060368.
Open DOI Search in Google Scholar Back to article
Birbrair A. Stem Cells Heterogeneity in Different Organs. Advances in Experimental Medicine and Biology. Springer. 2019.
Search in Google Scholar Back to article

Cardiac Stem Cell Therapy, Resident Progenitor Cells and the role of Cellular Signalling; a Review

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