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Effects of deep breathing on anxiety, pain, and vital signs in patients undergoing bone marrow aspiration Cover

Effects of deep breathing on anxiety, pain, and vital signs in patients undergoing bone marrow aspiration

Open Access
|Jul 2026

Figures & Tables

Figure 1.

The PRISMA diagram describing the selection of included literature. PRISMA, Preferred Reporting Items for Systematic Review and Meta-Analyzes.

Figure 2.

Study design of the intervention and control groups.

Note: Vital sign; **Visual analog scale; ***Bone marrow aspiration. DBT, deep breathing technique.

Table 1.

Demographic details of the study population, n (%).

Parameter/groupBreathing group (n = 30)Control group (n = 28)P
Age (years)51.8 ± 8.649.3 ± 10.80.353
Female23 (56.1)18 (43.9)0.301
Margie, yes27 (52.9)24 (47.1)0.857
Weight, kg (M ± SD)74.2 ± 10.977.1 ± 9.83.359
ASA class0.512
  I (%)18 (60)19 (67.9)
  II (%)12 (40)9 (32.1)
Diagnosis0.504
  Osteoarthritis knee25 (83.3)21 (75)
  Osteoarthritis hip5 (16.7)6 (21.4)
AVN01 (3.6)

1 Note: Data are mean ± SD or number (%); Use t student and Chi-square test to comparison between studies group; Significance level was 0.05; AVN, avascular necrosis; SD, standard deviation.

Table 2.

Comparison anxiety and pain between study groups.

VariableInterventionPlaceboMean differenceP
Anxiety19.81 ± 0.7522.45 ± 0.77−2.64 ± 1.080.018
VAS1.30 ± 1.513.4 ± 2.04−2.34 ± 0.46<0.001

1 Note: Data for anxiety variable represented mean ± standard error and for VAS represented mean ± SD. Mean difference is (Intervention - Placebo). Significance level was 0.05; SD, standard deviation; VAS, Visual Analog Scale.

Table 3.

Comparison variables before and after intervention in different study groups.

Groups and variableBeforeAfterMean differenceP
Intervention
  SBP132.2 ± 22.2114.3 ± 19.417.8 ± 14.02<0.001
  DBP85.4 ± 13.973.2 ± 11.912.17 ± 10.5<0.001
  HR80.6 ± 12.568.5 ± 7.912.03 ± 8.98<0.001
  O2sat97.03 ± 1.1596.17 ± 1.780.867 ± 2.250.044
Control
  SBP126.2 ± 17.01116.3 ± 26.59.96 ± 26.160.064
  DBP81.7 ± 12.779.7 ± 11.51.96 ± 9.20.289
  HR78.7 ± 14.0578.3 ± 13.10.462 ± 8.170.776
  O2sat96.92 ± 1.3897.04 ± 1.31−0.115 ± 1.330.664

1 Note: Data represented as mean ± SD. Mean difference is (before - after); Used paired t test for comparison before and after intervention. Significant level was 0.05; DBP diastolic blood pressure; HR, heart rate; O2sat, oxygen saturation; SBP, systolic blood pressure; SD, standard deviation.

DOI: https://doi.org/10.2478/FON-2026-0024 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368
Language: English
Page range: 205 - 212
Submitted on: Sep 9, 2025
Accepted on: Oct 11, 2025
Published on: Jul 3, 2026
Published by: Shanxi Medical Periodical Press
In partnership with: Paradigm Publishing Services

© 2026 Mostafa Javadi, Ali Parouhan, Seyedeh Esmat Hosseini, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.