Figure 1:
Figure 2:
Figure 3:
EC50 (±S_E_) values of pyrantel, bephenium, and morantel in the presence of GABA and carvacrol_
| Control | GABA 3 μM | GABA 3 μM + Carvacrol 100 μM | Wash | |
|---|---|---|---|---|
| Pyrantel (nM) | 8.44 ± 1.56 | 28.11 ± 1.61**** | 44.62 ± 2.70****++++ | 20.51 ± 2.34***oooo |
| Bephenium (μM) | 0.62 ± 0.11 | 0.96 ± 0.21 | 1.40 ± 0.12*** | 1.32 ± 0.09** |
| Morantel (nM) | 3.72 ± 1.73 | 5.69 ± 2.12 | 7.94 ± 2.35 | 15.81 ± 4.03*+ |
R max (g ± S_E_) values of pyrantel, bephenium, and morantel in the presence of GABA and carvacrol_
| Control | GABA 3 μM | GABA 3 μM + Carvacrol 100 μM | Wash | |
|---|---|---|---|---|
| Pyrantel | 1.52 ± 0.12 | 1.38 ± 0.20 | 0.47 ± 0.15****+++ | 0.77 ± 0.17**+ |
| Bephenium | 2.20 ± 0.30 | 2.18 ± 0.34 | 0.89 ± 0.22**++ | 1.15 ± 0.23*+ |
| Morantel | 1.16 ± 0.07 | 0.99 ± 0.11 | 0.39 ± 0.11****+++ | 0.59 ± 0.15***o |