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Soft tissue hematomas on ultrasound: a case-based review and practical guide to diagnosis Cover

Soft tissue hematomas on ultrasound: a case-based review and practical guide to diagnosis

Open Access
|Dec 2025

Figures & Tables

Fig. 1.

Ultrasound of the left rectus abdominis muscle demonstrating intramuscular thickening (6.8 × 1.6 cm) with heterogeneous hypoechoic areas (A) and no internal flow on CD (B), consistent with an intramuscular hematoma. Comparative imaging (C) confirms asymmetry relative to the contralateral side
Ultrasound of the left rectus abdominis muscle demonstrating intramuscular thickening (6.8 × 1.6 cm) with heterogeneous hypoechoic areas (A) and no internal flow on CD (B), consistent with an intramuscular hematoma. Comparative imaging (C) confirms asymmetry relative to the contralateral side

Fig. 2.

Ultrasound of the right pectoral region showing a large heterogeneous subfascial (yellow arrow) intramuscular (yellow bracket) collection (12 × 6 × 12 cm) without internal vascularity on CD, consistent with a subacute iatrogenic hematoma (A, B, C). Follow-up US performed one week later (D) demonstrates increased disorganization, internal echogenic strands, and persistent absence of vascular signal, confirming hematoma evolution
Ultrasound of the right pectoral region showing a large heterogeneous subfascial (yellow arrow) intramuscular (yellow bracket) collection (12 × 6 × 12 cm) without internal vascularity on CD, consistent with a subacute iatrogenic hematoma (A, B, C). Follow-up US performed one week later (D) demonstrates increased disorganization, internal echogenic strands, and persistent absence of vascular signal, confirming hematoma evolution

Fig. 3.

Ultrasound of the right rectus femoris muscle showing a heterogeneous hypoechoic lesion (1.2 × 1.6 × 2.7 cm) without internal flow on CD (A). Follow-up examinations at one (B) and four weeks (C) demonstrate progressive reduction in size (from 1.2 × 1.3 × 1 cm to 1.3 × 0.5 cm) and increasing echogenicity, consistent with resorptive hematoma evolution. Mild subcutaneous tissue edema persisted throughout the follow-up period. Comparative imaging (D) highlights muscle asymmetry and echotextural inhomogeneity, suggestive of evolving structural remodeling
Ultrasound of the right rectus femoris muscle showing a heterogeneous hypoechoic lesion (1.2 × 1.6 × 2.7 cm) without internal flow on CD (A). Follow-up examinations at one (B) and four weeks (C) demonstrate progressive reduction in size (from 1.2 × 1.3 × 1 cm to 1.3 × 0.5 cm) and increasing echogenicity, consistent with resorptive hematoma evolution. Mild subcutaneous tissue edema persisted throughout the follow-up period. Comparative imaging (D) highlights muscle asymmetry and echotextural inhomogeneity, suggestive of evolving structural remodeling

Fig. 4.

Ultrasound of the right gluteal region demonstrating a large subcutaneous anechoic collection (13.6 × 4.9 × 5.9 cm) with internal particulate content (A, B) and no flow on CD (C), consistent with a subacute hematoma
Ultrasound of the right gluteal region demonstrating a large subcutaneous anechoic collection (13.6 × 4.9 × 5.9 cm) with internal particulate content (A, B) and no flow on CD (C), consistent with a subacute hematoma

Fig. 5.

Ultrasound of the right thigh showing a large heterogeneous intramuscular collection within the biceps femoris muscle (4 × 5 × 10 cm), containing mixed hypoechoic and anechoic components (A) and presenting no internal vascularity on CD (B), suggestive of an intramuscular abscess
Ultrasound of the right thigh showing a large heterogeneous intramuscular collection within the biceps femoris muscle (4 × 5 × 10 cm), containing mixed hypoechoic and anechoic components (A) and presenting no internal vascularity on CD (B), suggestive of an intramuscular abscess

Fig. 6.

Ultrasound of the medial aspect of the right lower leg showing a large polylobulated subcutaneous mass (5.3 × 4.2 × 7.4 mm) with internal septations and a small calcification (A). CD imaging demonstrates both peripheral and internal vascularity (B), consistent with a soft-tissue sarcoma
Ultrasound of the medial aspect of the right lower leg showing a large polylobulated subcutaneous mass (5.3 × 4.2 × 7.4 mm) with internal septations and a small calcification (A). CD imaging demonstrates both peripheral and internal vascularity (B), consistent with a soft-tissue sarcoma

Fig. 7.

Ultrasound of the abdominal wall demonstrating a right-sided anechoic subcutaneous collection consistent with a postoperative seroma (A) and a left-sided collection with internal echogenic strands and particulate content consistent with a hematoma (B)
Ultrasound of the abdominal wall demonstrating a right-sided anechoic subcutaneous collection consistent with a postoperative seroma (A) and a left-sided collection with internal echogenic strands and particulate content consistent with a hematoma (B)

Fig. 8.

Ultrasound examination of the posterior medial calf demonstrating a large, inhomogeneous hypoechoic fluid collection (17 × 4 × 2 cm) extending proximally toward the popliteal fossa (A), without internal vascular signal on CD imaging (B). Findings are consistent with a ruptured Baker’s cyst with associated surrounding subcutaneous edema
Ultrasound examination of the posterior medial calf demonstrating a large, inhomogeneous hypoechoic fluid collection (17 × 4 × 2 cm) extending proximally toward the popliteal fossa (A), without internal vascular signal on CD imaging (B). Findings are consistent with a ruptured Baker’s cyst with associated surrounding subcutaneous edema

Sonographic evolution of soft tissue hematomas over time

StageApproximate timeframeB-mode US appearanceColor Doppler findings
Acute0–48 hoursAnechoic or mildly hypoechoic; may show fine internal echoes from fresh clot; usually compressible; poorly defined margins in early phaseAbsent internal flow; possible mild peripheral hyperemia due to surrounding inflammation
Early subacute3–7 daysHeterogeneous echotexture with internal echogenic sediment, fine septations, and possible fluid–fluid levelsNo internal vascularity; peripheral hyperemia may persist
Late subacute1–3 weeksIncreasingly complex internal echoes; formation of thin capsule; partial organization of clotGenerally avascular internally; mild peripheral flow possible
Chronic/organized>3–6 weeksWell-defined margins; hypoechoic or mixed echogenicity with capsule; possible peripheral calcifications or echogenic septaAbsent internal flow; thin peripheral vascular rim may be reactive
DOI: https://doi.org/10.15557/jou.2025.0038 | Journal eISSN: 2451-070X | Journal ISSN: 2084-8404
Language: English
Submitted on: Jul 17, 2025
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Accepted on: Dec 7, 2025
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Published on: Dec 31, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Federica Masino, Gabriele Fanigliulo, Chiara Locorotondo, Manuela Montatore, Valeria Buonocore, Pasquale Favia, Giuseppe Guglielmi, Eluisa Muscogiuri, published by MEDICAL COMMUNICATIONS Sp. z o.o.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.