Fig. 1.
Comparison of obese patients with hepatic steatosis and without hepatic steatosis in terms of anthropometric measurements, laboratory values, and imaging findings
| Variables | NHSOG (n = 30) | HSOG (n = 46) | p-value |
|---|---|---|---|
| Age | 12.6 ± 2.7 | 13.0 ± 2.6 | 0.698 |
| Gender (M/F) | 13/17 | 24/22 | 0.474 |
| Weight (kg) | 67.5 ± 12.3 | 84.7 ± 21.1 | 0.003 |
| Height (cm) | 157.5 ± 9.9 | 160.5 ± 13.3 | 0.412 |
| BMI | 27.1 ± 2.4 | 32.5 ± 4.2 | 0.000 |
| BMI standard deviation scores | 1.8 ± 0.4 | 2.2 ± 0.3 | 0.001 |
| BMI percentile | 95.9 ± 3.8 | 98.0 ± 1.8 | 0.023 |
| Glucose (70–105 mg/dL) | 91.8 ± 11.6 | 92.0 ± 10.8 | 0.699 |
| Insulin (2.6–24.9 μIU/ml) | 21.3 ± 11.1 | 24.3 ± 17.8 | 0.532 |
| HOMA-IR | 4.8 ± 4.0 | 5.5 ± 4.3 | 0.379 |
| Triglyceride (0–150 mg/dL) | 113 ± 47.6 | 122.6 ± 54.1 | 0.578 |
| LDL (0–130 mg/dL) | 80.1 ± 21.6 | 91.1 ± 24.9 | 0.151 |
| HDL (0–55 mg/dL) | 45.6 ± 7.1 | 46.9 ± 9.0 | 0.482 |
| AST (0–50 mg/dL) | 21.8 ± 5.1 | 26.4 ± 15.8 | 0.034 |
| ALT (0–50 mg/dL) | 20.1 ± 7.2 | 32.6 ± 23.1 | 0.007 |
| Liver size (cm) | 14.0 ± 1.7 | 15.3 ± 1.6 | 0.014 |
| Liver stiffness (kPa) | 4.9 ± 0.6 | 6.2 ± 1.7 | 0.000 |
| SII | 480.0 ± 264.2 | 601 ± 288.5 | 0.000 |
| PIV | 297.5 ± 197.7 | 432.1 ± 259.0 | 0.000 |
Comparison of obese patients with no hepatic steatosis (sonographically grade 0 HS), sonographically grade 1, and 2 HS in terms of anthropometric measurements, laboratory values, and imaging findings
| Variables | Sonographically grade 0 HS (n = 30) | Sonographically grade 1 HS (n = 30) | Sonographically grade 2 HS (n = 16) | ANOVA |
|---|---|---|---|---|
| Age | 12.6 ± 2.7 | 13.0 ± 2.9 | 13.4 ± 2.1 | 0.434 |
| Gender (M/F) | 13/17 | 17/13 | 7/9 | 0.566 |
| Weight (kg) | 67.5 ± 12.3 | 80.2 ± 22.4 | 94.4 ± 15.0 | 0.003b |
| Height (mm) | 157.5 ± 9.9 | 157.7 ± 15.4 | 166.0 ± 5.5 | 0.244 |
| BMI | 27.1 ± 2.4 | 31.7 ± 3.8 | 33.9 ± 4.8 | 0.002a,b |
| BMI Z-score | 1.8 ± 0.4 | 2.3 ± 0.4 | 2.7 ± 0.2 | 0.005a,b |
| BMI percentile | 95.9 ± 3.8 | 97.9 ± 2.2 | 98.2 ± 0.7 | 0.140 |
| Glucose (70–105 mg/dL) | 91.8 ± 11.6 | 90.2 ± 9.6 | 96.3 ± 13.3 | 0.436 |
| Insulin (2.6–24.9 μIU/ml) | 21.3 ± 11.1 | 21.5 ± 15.8 | 32.1 ± 21.2 | 0.210 |
| HOMA-IR | 4.8 ± 3.2 | 4.9 ± 3.8 | 7.6 ± 3.5 | 0.002b,c |
| Triglyceride (0–150 mg/dL) | 113 ± 47.6 | 122.6 ± 54.1 | 154.4 ± 58.6 | 0.005b,c |
| LDL (0–130 mg/dL) | 80.1 ± 21.6 | 87.6 ± 16.4 | 98.1 ± 37.3 | 0.210 |
| HDL (0–55 mg/dL) | 45.6 ± 7.1 | 48.7 ± 6.5 | 44.1 ± 6.9 | 0.266 |
| AST (0–50 mg/dL) | 21.8 ± 5.1 | 25.9 ± 17.1 | 27.3 ± 16.5 | 0.311 |
| ALT (0–50 mg/dL) | 20.1 ± 7.2 | 30.7 ± 23.2 | 38.9 ± 27.6 | 0.003b |
| Liver size (cm) | 14.0 ± 1.7 | 14.6 ± 1.4 | 16.6 ± 1.0 | 0.016b,c |
| Liver stiffness (kPa) | 4.9 ± 0.6 | 5.2 ± 0.9 | 7.5 ± 1.9 | 0.000b,c |
| SII | 480.0 ± 264.2 | 568.9 ± 341.5 | 695.0 ± 297.3 | 0.000a,b,c |
| PIV | 297.5 ± 197.7 | 388.1 ± 289.0 | 550.1 ± 341.8 | 0.000a,b,c |
Comparison of the obese patient group and normal-weight patient group in terms of anthropometric measurements and imaging findings
| Variables | OG (n = 76) | NG (n = 44) | p-value |
|---|---|---|---|
| Age | 12.8 ± 2.6 | 12.9 ± 2.8 | 0.940 |
| Gender (M/F) | 37/39 | 21/23 | 0.710 |
| BMI | 30.0 ± 4.3 | 18.9 ± 3.4 | 0.000 |
| Liver size (cm) | 14.7 ± 1.7 | 12.7 ± 1.4 | 0.000 |
Comparison of obese patients without hepatic steatosis and normal-weight patients in terms of anthropometric measurements and imaging findings
| Variables | NHSOG (n = 30) | NG (n = 44) | p-value |
|---|---|---|---|
| Age | 12.6 ± 2.7 | 12.8 ± 2.8 | 0.568 |
| Gender (M/F) | 13/17 | 21/23 | 0.910 |
| BMI | 27.1 ± 2.4 | 18.9 ± 3.4 | 0.000 |
| Liver size (cm) | 14.0 ± 1.7 | 12.7 ± 1.4 | 0.008 |
| Liver stiffness (kPa) | 4.9 ± 0.6 | 4.6 ± 0.9 | 0.690 |