Optimization the Process of Microencapsulation of Bifidobacterium bifidum BB01 by Box-Behnken Design

Chen, He; Ma, Donglin; Li, Yichao; Liu, Yu; Wang, Ye

doi:10.1515/aucft-2016-0012

Abstract

The effects of cell suspension-alginate ratios, sodium erythorbate, and inulin on encapsulation yield of microcapsules of Bifidobacterium bifidum BB01 were studied by Box-Behnken design. The experimental results indicated that cell suspension-alginate ratios, sodium erythorbate and inulin had a significant impact on encapsulation yield, and the embedding yield could be enhanced significantly in the condition of 1:3 cell suspension-alginate ratios, 0.12% sodium erythorbate, and 6% inulin. The optimal embedding yields of microencapsulation of B. bifidum BB01 were observed to be 81.52%, that values were very close to the expected values 81.81%, so the method was effective.

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Optimization the Process of Microencapsulation of Bifidobacterium bifidum BB01 by Box-Behnken Design

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