Figure 1
Conceptualization of myocardial recovery. Normal cardiac milieu adaptation during heart failure results in abnormalities of distinct factors such as CM and NCM, the ECM, and the modified LV geometry. Myocardial recovery could manifest in two forms: (1) remission, where further heart failure events can reoccur, or (2) myocardial recovery that is free from further cardiac insufficiencies. Modified from Mann et al.66 CM: cardiomyocytes; NCM: non-cardiomyocytes; ECM: extracellular matrix; LV: left ventricular