This book provides a comprehensiveoverview of the localized drug delivery system landscape. The 10 chapters providea detailed introduction in polymers, nanostructures and nanocomposites fordeveloping localized controlled drug delivery systems (LCDDSs) in the form ofstimuli-responsive delivery systems, targeted drug delivery systems or thecombination of both. A discussion onmanufacturing techniques, optimization, challenges and adaptation of LCDDSs forthe treatment of a wide range of diseases is also included. This simple and informative resource conveysan understanding about designing novel drug delivery systems to students inadvanced pharmacology, biotechnology, materials science and biochemistry studyprograms. Readers will be equipped with the knowledge of regulating drugrelease rates to get a desired pharmacological profile, that helps a researcherto ensure a high therapeutic effectiveness. The detailed information about variousdrug delivery systems and a compilation of recent literature sources also pavesthe way for research scholars to construct a drug targeting framework for theirresearch plans.