Over the last few decadesnumerous nanoparticle platforms have been studied for their use in therapeutic applications. This book deals with the description of the construction of technical systems that combines different functionalities which bring liposomespolymer-drug conjugatespolymer-protein conjugatesdendrimerspolymeric micellespolymerosomes and other nanoparticles into the realm of nanotechnology properas opposed to traditional pharmacology or supramolecular chemistry. The volume additionally covers topics such as passive and active targetingthe strategies used for drug targetingand the synthesis and characterization of polymeric nanoparticle platforms. Targeted polymeric nanomedicines have shown exciting results in preclinical studiesdemonstrating their potential as therapeutic carriers. Thereforethe development of polymeric nanomedicines as therapeutic agents has generated great enthusiasm both in academia and industry.
The book is systematically divided into chapters devoted to a class of polymeric nanomedicines. Each chapter also describes relevant aspects relating to drug design and targeting of polymeric nanomedicines wherever possible.
In additiona series of chapters concerning the contribution of polymeric nanomedicines in the treatment of several categories of diseases including cancerinflammatoryrenalimmunological diseasesand brain disorders is also presented.
Key features of this book include:
- A comprehensive and cutting-edge overview of polymeric nanomedicines available in a single dedicated volume
- Discussions on advances in drug delivery systems for a variety of diseases
- more than 2000 referencestablesequationsand drawings
Readerswhether beginners or expertswill find in this bookcontemporary and relevant information regarding the synthesisevaluation and applications of polymeric nanomedicines. Supplemented with extensive bibliographic referencestables and figuresthis book is an essential and incomparable reference for medicinal chemistsbiologistsand medical (oncologic) researchersas well as for scientistsundergraduate and graduate students in the field of medical bioengineering and polymer nanoscience.