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Intravenous insulin protocol reduces time to target glucose in critically ill trauma and burn patients Cover

Intravenous insulin protocol reduces time to target glucose in critically ill trauma and burn patients

Open Access
|Jul 2026

Figures & Tables

Fig. 1.

Time to Target Glucose in the pre- and post-implementation of Intravenous Insulin Protocol.

Table 1.

Comparison of Mean and Standard Deviation of the Outcomes Pre (Non-IIP group) and Post-Implementation of IIP (IIP group)

Insulin ProtocolTime to Target Glucose (SD)Hyperglycemia rate within 7 days of AdmissionHypoglycemia rate within 7 days of AdmissionHospital LOSICU LOS
Post-Implementation (IIP)10.06 (5.69)56.1% (0.30)0.4% (0.1)17.09 (18.67)11.97(18.48)
Pre-Implementation (Non-IIP)24.96 (34.59)45.3% (0.28)0.8% (0.8)19.81 (21.55)13.84(18.37)
Fig. 2.

Percentage of Hyperglycemia in the pre-and post-implementation of Intravenous Insulin Protocol.

Fig. 3.

Percentage of Hypoglycemia in the pre- and post-implementation of Intravenous Insulin Protocol.

Table 2.

Comparison of Mean and Standard Deviation Percentages of Hyperglycemia and Hypoglycemia During Intravenous and Subcutaneous Insulin Administrations Before and After Protocol Implementation

Insulin Route of AdministrationsHyperglycemic events (SD)Hypoglycemic events (SD)
IV Insulin (Post-Implementation)9.8 % (0.14)0.2% (0.02)
SubQ Insulin (Post-Implementation)56.1 % (0.3)0.4% (0.01)
SubQ Insulin (Pre-Implementation45.3% (0.28)0.8% (0.02)
Table 3.

Mortality rates in hospital, ICU, and 30 days post-hospitalization before and after implementation of the insulin protocol

Insulin ProtocolHospitalICU30 days post-hospitalization
Post-Implementation (IIP)18.8 %12.5%18.8%
Pre-Implementation18.6%16.9%23.7%
DOI: https://doi.org/10.62838/jccm-2026-0027 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 359 - 367
Submitted on: Mar 5, 2026
Accepted on: Apr 12, 2026
Published on: Jul 27, 2026
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Oluwafolaranmi E. Sodade, Connor J. English, Cindy L. Austin, Charles A. Lunday, Yang Wang, Brian B. Draper, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.