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From Physical Frailty to Psychosocial Maladaptation: Predicting Mental Reserve and Quality of Life in Patients with Inflammatory Bowel Diseases Cover

From Physical Frailty to Psychosocial Maladaptation: Predicting Mental Reserve and Quality of Life in Patients with Inflammatory Bowel Diseases

Open Access
|Dec 2025

References

  1. Amon, J.N., Ridley, E.J. (2022). Clinimetrics: Clinical Frailty Scale. J Physiother, 68(2):147. https://doi.org/10.1016/j.jphys.2021.10.003
  2. Di Raimondo, D., Pirera, E., Pintus, C., De Rosa, R., Profita, M., Musiari, G., Siscaro, G., & Tuttolomondo, A. (2023). The Role of the Cumulative Illness Rating Scale (CIRS) in Estimating the Impact of Comorbidities on Chronic Obstructive Pulmonary Disease (COPD) Outcomes: A Pilot Study of the MACH (Multidimensional Approach for COPD and High Complexity) Study. Journal of Personalized Medicine, 13. https://doi.org/10.3390/jpm13121674.
  3. Fons, A., Kalisvaart, K., & Maljaars, J. (2023). Frailty and Inflammatory Bowel Disease: A Scoping Review of Current Evidence. Journal of Clinical Medicine, 12(2), 533. https://doi.org/10.3390/jcm12020533
  4. Goodman, W. A., Erkkila, I. P., & Pizarro, T. T. (2020). Sex matters: impact on pathogenesis, presentation and treatment of inflammatory bowel disease. Nature reviews. Gastroenterology & hepatology, 17(12), 740–754. https://doi.org/10.1038/s41575-020-0354-0
  5. Huang, X., Xiao, M., Jiang, B., Wang, X., Tang, X., Xu, X., Chen, Y., Wang, S., Yan, S., Wang, S., Wang, J., & Zhang, P. (2022). Prevalence of frailty among patients with inflammatory bowel disease and its association with clinical outcomes: a systematic review and meta-analysis. BMC gastroenterology, 22(1), 534. https://doi.org/10.1186/s12876-022-02620-3
  6. Kang, H., Fischer, I. C., Esterlis, I., Kolyshkina, A., Ponomarenko, L., Chobanian, A., Vus, V., & Pietrzak, R. H. (2024). Helping the Helpers: Mental Health Challenges of Psychosocial Support Workers During the Russian-Ukrainian War. Disaster medicine and public health preparedness, 18, e95. https://doi.org/10.1017/dmp.2024.68
  7. Kochar, B., Cai, W., Cagan, A., & Ananthakrishnan, A. N. (2020). Frailty is independently associated with mortality in 11 001 patients with inflammatory bowel diseases. Alimentary pharmacology & therapeutics, 52(2), 311–318. https://doi.org/10.1111/apt.15821
  8. Lenti, M. V., Brera, A. S., Broglio, G., Bertolino, G., Di Sabatino, A., Klersy, C., & Corazza, G. R. (2025). Factors associated with comorbidity in hospitalized and non-hospitalized inflammatory bowel disease patients: A single-center, preliminary study. Journal of multimorbidity and comorbidity, 15, 26335565251365040. https://doi.org/10.1177/26335565251365040
  9. Li, K., Feng, C., Chen, H., Feng, Y., & Li, J. (2022). Trends in Worldwide Research in Inflammatory Bowel Disease Over the Period 2012–2021: A Bibliometric Study. Frontiers in medicine, 9, 880553. https://doi.org/10.3389/fmed.2022.880553
  10. Li, X., & Ma, L. (2024). From biological aging to functional decline: Insights into chronic inflammation and intrinsic capacity. Ageing research reviews, 93, 102175. https://doi.org/10.1016/j.arr.2023.102175
  11. Linn, B. S., Linn, M. W., & Gurel, L. (1968). Cumulative illness rating scale. Journal of the American Geriatrics Society, 16(5), 622–626. https://doi.org/10.1111/j.1532-5415.1968.tb02103.x
  12. Liu, C., Zhang, J., Chen, M., An, P., Xiang, J., Yu, R., Zeng, S., Wei, S., Deng, B., Liu, Z., Jiang, C., Shi, J., Wu, K., & Dong, W. (2023). Gender Differences in Psychological Symptoms and Quality of Life in Patients with Inflammatory Bowel Disease in China: A Multicenter Study. Journal of Clinical Medicine, 12. https://doi.org/10.3390/jcm12051791.
  13. Matiashova, L., Tsagkaris, C., Essar, M. Y., Romash, I. B., & Vus, V. I. (2022). Achilles in Ukraine: Concerns and priorities over the long-term implications of trauma. The International journal of health planning and management, 37(6), 3369–3371. https://doi.org/10.1002/hpm.3562
  14. Qian, A. S., Nguyen, N. H., Elia, J., Ohno-Machado, L., Sandborn, W. J., & Singh, S. (2021). Frailty Is Independently Associated with Mortality and Readmission in Hospitalized Patients with Inflammatory Bowel Diseases. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association, 19(10), 2054–2063.e14. https://doi.org/10.1016/j.cgh.2020.08.010
  15. Rayan, R. A., Zafar, I., Tsagkaris, C., Romash, I. (2021). Internet of Things for Mitigating Climate Change Impacts on Health. In Artificial Intelligence and Internet of Things. 2021:317–330. CRC Press http://dx.doi.org/10.1201/9781003097204-14
  16. Rayan, R.A., Zafar, I. and Romash, I.B. (2021). Healthcare System 4.0 Perspectives on COVID-19 Pandemic. In Enabling Healthcare 4.0 for Pandemics (eds A. Juneja, V. Bali, S. Juneja, V. Jain and P. Tyagi). https://doi.org/10.1002/9781119769088.ch2
  17. Rockwood, K., & Theou, O. (2020). Using the Clinical Frailty Scale in Allocating Scarce Health Care Resources. Canadian geriatrics journal : CGJ, 23(3), 210–215. https://doi.org/10.5770/cgj.23.463
  18. Rockwood, K., Song, X., MacKnight, C., Bergman, H., Hogan, D. B., McDowell, I., & Mitnitski, A. (2005). A global clinical measure of fitness and frailty in elderly people. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 173(5), 489–495. https://doi.org/10.1503/cmaj.050051
  19. Romash, I. (2023). Assessment of comorbid profile, quality of life and social functioning in patients with schizophrenia and schizotypal disorders. Medicni Perspektivi, 28(1), 131–141. https://doi.org/10.26641/2307-0404.2023.1.276043
  20. Romash, I. (2025). Lipid peroxidation, MMP-9 activity, and BDNF level in patients with paranoid schizophrenia depending on the duration of the disease. The Odessa Medical Journal. 27–34. https://doi.org/10.32782/2226-2008-2025-4-4
  21. Salvatori, S., Marafini, I., Venuto, C., Laudisi, F., Neri, B., Lavigna, D., Franchin, M., De Cristofaro, E., Biancone, L., Calabrese, E., Giannarelli, D., & Monteleone, G. (2023). Frail Phenotype in Patients With Inflammatory Bowel Disease. Inflammatory bowel diseases, 29(10), 1555–1562. https://doi.org/10.1093/ibd/izac242
  22. Simon J. Hong, Seymour Katz. Frailty, Thy Diagnosis Is Uncertain: Impact on IBD Readmission and Mortality. Digestive Diseases and Sciences (2021) 66:4070–4071 https://doi.org/10.1007/s10620-021-06926-2
  23. Trishch, V., Solomchak, D., Romash, I., & Romash, I. (2025). Erectile dysfunction and mental health of men [Erektilná dysfunkcia a mentálne zdravie mužov]. Lekarsky Obzor, 74(7), 289–295. https://www.lekarskyobzor.sk/prezentacie/2025/lekarsky-obzor-2025-07/2025-lekarsky-obzor-07-trishch.pdf
  24. Tsagkaris, C., Papazoglou, A. S., Romash, I. B., Moysidis, D. V., Romash, I. R., Gabunia, L., & Gorbatiuk, T. (2021). The bone-brain axis? Biopsychosocial aspects of orthopedics and a mental wellbeing action plan in musculoskeletal care Wiadomosci lekarskie (Warsaw, Poland: 1960), 74(11 cz 1), 2829–2835. DOI: https://doi.org/10.36740/WLek20211112
  25. Tymkiv, I. V., Blyzniuk, M. V., Botsiurko, Y. V., Tymkiv, I.S., Romash, I. B., & Vengrovych, O. Z. (2025). Motivational factors and challenges in medical students' learning. Psychiatry Neurology and Medical Psychology, 30, 530–537. https://doi.org/10.26565/2312-5675-2025-30-08
Language: English
Page range: 222 - 234
Submitted on: Sep 5, 2025
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Accepted on: Dec 26, 2025
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Published on: Dec 31, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Iryna Romash, Ihor Sarapuk, Ivan Romash, Oleksandr Kudyn, Vasyl Mishchuk, published by International Platform on Mental Health
This work is licensed under the Creative Commons Attribution 4.0 License.