Have a personal or library account? Click to login
Compression-dependency of soft tissue bioimpedance for in-vivo and in-vitro tissue testing Cover

Compression-dependency of soft tissue bioimpedance for in-vivo and in-vitro tissue testing

Journal of Electrical Bioimpedance
Volume 6 (2015): Issue 1 (January 2015)
By: Sepideh M. Moqadam,  Parvind Grewal,  Majid Shokoufi and  Farid Golnaraghi  
Open Access
|Dec 2015

Figures & Tables

Fig.1

a) The electrical impedance setup b) The electrical impedance spectroscope (HF2IS) c) The designed and prototyped probe consisting of 2 Ag/AgCl electrodes and 6 temperature sensors (temperature electrodes were not used in this study)
a) The electrical impedance setup b) The electrical impedance spectroscope (HF2IS) c) The designed and prototyped probe consisting of 2 Ag/AgCl electrodes and 6 temperature sensors (temperature electrodes were not used in this study)

Fig.2

a) Imaginary part of admittance versus its real part (Cole arc). b) Cole model circuit.
a) Imaginary part of admittance versus its real part (Cole arc). b) Cole model circuit.

Fig.3

Stress versus indentation of in-vivo bicep of one subject.
Stress versus indentation of in-vivo bicep of one subject.

Fig.4

Chicken breast tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.17 w+0.9 and the Pearson product of the linear relationship is 0.972 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=-0.081 w+1 and the Pearson product of the linear relationship is -0.986 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=0.19 w+0.91 and the Pearson product of the linear relationship is 0.975.
Chicken breast tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.17 w+0.9 and the Pearson product of the linear relationship is 0.972 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=-0.081 w+1 and the Pearson product of the linear relationship is -0.986 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=0.19 w+0.91 and the Pearson product of the linear relationship is 0.975.

Fig.5

Rat breast tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.031 w+0.99 and the Pearson product of the linear relationship is 0.977 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=-0.033 w+1 and the Pearson product of the linear relationship is -0.998 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=0.079 w+0.97 and the Pearson product of the linear relationship is 0.992.
Rat breast tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.031 w+0.99 and the Pearson product of the linear relationship is 0.977 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=-0.033 w+1 and the Pearson product of the linear relationship is -0.998 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=0.079 w+0.97 and the Pearson product of the linear relationship is 0.992.

Fig.6

Left Forearm Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.1 w+0.78 and the Pearson product of the linear relationship is 0.983 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.023 w+0.95 and the Pearson product of the linear relationship is 0.924 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.031 w+1.1 and the Pearson product of the linear relationship is -0.999.
Left Forearm Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.1 w+0.78 and the Pearson product of the linear relationship is 0.983 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.023 w+0.95 and the Pearson product of the linear relationship is 0.924 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.031 w+1.1 and the Pearson product of the linear relationship is -0.999.

Fig.7

Right Forearm Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.1 w+0.76 and the Pearson product of the linear relationship is 0.918 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.024 w+0.95 and the Pearson product of the linear relationship is 0.993 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.032 w+1.1 and the Pearson product of the linear relationship is -0.997.
Right Forearm Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.1 w+0.76 and the Pearson product of the linear relationship is 0.918 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.024 w+0.95 and the Pearson product of the linear relationship is 0.993 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.032 w+1.1 and the Pearson product of the linear relationship is -0.997.

Fig.8

Left Bicep Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.69 w-0.65 and the Pearson product of the linear relationship is 0.979 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.029 w+0.93 and the Pearson product of the linear relationship is 0.969 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.063 w+1.1 and the Pearson product of the linear relationship is -0.998.
Left Bicep Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.69 w-0.65 and the Pearson product of the linear relationship is 0.979 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.029 w+0.93 and the Pearson product of the linear relationship is 0.969 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.063 w+1.1 and the Pearson product of the linear relationship is -0.998.

Fig.9

Right Bicep Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.7 w-0.77 and the Pearson product of the linear relationship is 0.951 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.03 w+0.93 and the Pearson product of the linear relationship is 0.986 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.057 w+1.1 and the Pearson product of the linear relationship is -0.987.
Right Bicep Tissue, the correlation of compression-dependent Cole parameters normalized to their values at the first pressure level and tissue displacements. (a) compression-dependent extracellular resistance versus tissue displacement. The correlation is: Normalized Rext=0.7 w-0.77 and the Pearson product of the linear relationship is 0.951 (b) compression-dependent intracellular resistance versus tissue displacement. The correlation is: Normalized Rint=0.03 w+0.93 and the Pearson product of the linear relationship is 0.986 (c) compression-dependent membrane capacitance versus tissue displacement. The correlation is: Normalized Cm=-0.057 w+1.1 and the Pearson product of the linear relationship is -0.987.

Averaged Cole parameters by LAD method at the first pressure level and the standard deviations

Samples or SubjectsFitting Results
Rext (Ω)Rint (Ω)Cm (nF)
Chicken Breasts537.85 ± 23.19512.34 ± 24.327.91 ± 0.50
Rat Breasts565.54 ± 18.19675.83 ± 98.9330.7 ± 14.9
Left Forearms2612508.42 ± 359731.87986.46 ± 189.3416.46 ± 6.19
Right Forearms2125924.31 ± 189807.62970.02 ± 183.8918.45 ± 8.99
Left Biceps7577699.16 ± 180562.621386.3 ± 299.125914.83 ± 7.65
Right Biceps7563298.20 ± 121059.831252.9 ± 437.7215.26 ± 8.53
DOI: https://doi.org/10.5617/jeb.1489 | Journal eISSN: 1891-5469
Journal RSS Feed
Language: English
Page range: 22 - 32
Submitted on: Mar 31, 2015
Published on: Dec 18, 2015
Published by: University of Oslo
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
Bioimpedance,
soft tissue,
compression,
electrical impedance spectroscopy
Related subjects:
Engineering,
Bioengineering and biomedical engineering,
Biomedical electronics,
Life sciences,
Biophysics,
Medicine,
Biomedical engineering,
Physics,
Spectroscopy and metrology

© 2015 Sepideh M. Moqadam, Parvind Grewal, Majid Shokoufi, Farid Golnaraghi, published by University of Oslo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Previous articleVolume 6 (2015): Issue 1 (January 2015)Next article